CAS 96206-92-7: MPEP

Description: MPEP, or 2-Methyl-6-(phenylethynyl)pyridine, is a chemical compound recognized for its role as a selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is often studied in the context of neurological research, particularly for its potential implications in treating conditions such as anxiety, depression, and other neuropsychiatric disorders. MPEP is characterized by its pyridine ring structure, which is substituted with a phenylethynyl group and a methyl group, contributing to its pharmacological properties. The compound is typically found in a solid state and is soluble in organic solvents. Its mechanism of action involves modulating glutamate signaling, which is crucial for synaptic plasticity and cognitive functions. Due to its specificity for mGluR5, MPEP serves as a valuable tool in pharmacological studies aimed at understanding glutamate-related pathways in the brain. As with many research chemicals, safety and handling precautions are essential when working with MPEP in laboratory settings.

Formula: C₁₄H₁₁N

InChI: InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3

InChI key: InChIKey=NEWKHUASLBMWRE-UHFFFAOYSA-N

SMILES: C(#CC=1C=CC=CC1)C=2N=C(C=CC2)C

Synonyms:

• 2-Methyl-6-(2-phenylethynyl)pyridine
• 2-Methyl-6-(phenylethynyl)pyridine
• 2-Picoline, 6-phenylethynyl-
• Pyridine, 2-methyl-6-(2-phenylethynyl)-
• Pyridine, 2-methyl-6-(2-phenylethynyl)-, hydrochloride (1:1)
• Pyridine, 2-methyl-6-(phenylethynyl)-

MPEP

CAS: 96206-92-7

• Formula: C₁₄H₁₁N
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 193.2438

2-Methyl-6-(Phenylethynyl)Pyridine

CAS: 96206-92-7

• Molecular weight: 193.24g/mol

MPEP

CAS: 96206-92-7

• Purity: ≥98%
• Molecular weight: 193.24g/mol

MPEP

CAS: 96206-92-7

• Purity: 97%
• Molecular weight: 193.24899291992188

2-Methyl-6-(phenylethynyl)pyridine

CAS: 96206-92-7

• Formula: C₁₄H₁₁N
• Purity: >98.0%(GC)
• Color and Shape: White to Yellow to Orange powder to crystal
• Molecular weight: 193.25

MPEP

CAS: 96206-92-7

MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable …

• Formula: C₁₄H₁₁N
• Purity: 99.54%
• Color and Shape: Solid
• Molecular weight: 193.24

MPEP

CAS: 96206-92-7

mGluR5 antagonist

• Formula: C₁₄H₁₁N
• Purity: Min. 95%
• Color and Shape: White/Off-White Solid
• Molecular weight: 193.24 g/mol