GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 266 products for "GluR".
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AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Formula:C25H28F3N5O6SPurity:99.19%Color and Shape:SolidMolecular weight:583.58NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurity:97.32% - 97.60%Color and Shape:Brown SolidMolecular weight:380.2415Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Formula:C6H10N2O2Purity:97.16% - 99.98%Color and Shape:SolidMolecular weight:142.1558Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Formula:C18H13ClFN3Purity:98.35%Color and Shape:SolidMolecular weight:325.767γ-DGG acetate
CAS:gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Formula:C9H16N2O7Purity:99.92%Color and Shape:SolidMolecular weight:264.2325Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Formula:C11H12N2O2Purity:99.67%Color and Shape:White SolidMolecular weight:204.23LY339434 HCl
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)Formula:C18H20ClNO4Purity:97.10% - 97.19%Color and Shape:SoildMolecular weight:349.81Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Formula:C21H11F6N5Purity:99.77%Color and Shape:SolidMolecular weight:447.336(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatalFormula:C10H10ClNO6Purity:99.74% - 99.83%Color and Shape:SolidMolecular weight:275.64DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Formula:C8H10ClNO4Purity:99.55% - 99.59%Color and Shape:SolidMolecular weight:219.622ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SolidMolecular weight:306.33KM02894
CAS:KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.Formula:C7H9N3OS2Purity:99.98%Color and Shape:SolidMolecular weight:215.296VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.Formula:C20H10Cl3N3O3Purity:99.61%Color and Shape:SolidMolecular weight:446.67(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).Formula:C20H17F2N3O2Purity:99.87%Color and Shape:SolidMolecular weight:369.3647mGluR1 activator-1
mGluR1activator-1 is a stable vitamin K analog and mGluR1 activator capable of crossing the blood-brain barrier. It strongly activates transcription through steroid and xenobiotic receptors and retinoic acid receptors, effectively inducing neurogenesis in neural progenitor cells in mice. mGluR1activator-1 is applicable in studying neurodegenerative diseases, such as Alzheimer's.Color and Shape:Odour SolidMMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purity:99.88%Color and Shape:Yellow SolidMolecular weight:369.8GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:White SolidMolecular weight:395.71(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formula:C22H15ClN2O2Color and Shape:SolidMolecular weight:374.82MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18
