Ion Channel
Ion channels are specialized proteins that form pores in cell membranes, allowing the selective passage of ions such as sodium, potassium, calcium, and chloride. These channels play a critical role in various physiological processes, including nerve impulse transmission, muscle contraction, and the regulation of cellular homeostasis. Ion channels are essential targets in drug discovery, particularly in the treatment of neurological disorders, cardiovascular diseases, and pain management. At CymitQuimica, we offer a wide range of high-quality ion channel proteins and related reagents to support your research and drug development projects.
Found 107 products of "Ion Channel"
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(-)-Sparteine hydroiodide
CAS:Sparteine hydroiodide is the salt form of sparteine. This compound acts as an inhibitor of voltage-gated sodium channels. In organic chemisty, it is used for chiral synthesis.Formula:C15H26N2•HIPurity:Min. 95%Molecular weight:362.29 g/molPiracetam - Bio-X ™
CAS:Controlled ProductPiracetam is a nootropic drug that is used for the treatment of sickle cell disease, alcohol dependence and as a cognitive enhancer. This drug is a cyclic derivative of GABA and has neuroprotective and anticonvulsant properties. Piracetam has been said to improve neuronal plasticity.Formula:C6H10N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:142.16 g/molKainic acid monohydrate
CAS:Agonist of kainate receptors, a subclass of ionotropic glutamate receptors with neuroexcitatory action. At high concentrations, it can induce seizures and act as neurotoxin, causing neuron death due to overstimulation.Formula:C10H15NO4·H2OPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:231.25 g/molAmbroxol HCl - Bio-X ™
CAS:Ambroxol is a secretolytic agent that is used in the treatment of respiratory diseases and chronic coughs. Ambroxol has been shown to inhibit the NO-dependent activation of soluble guanylate cyclase so that the airway is not inflamed or its functions are not disturbed. Also, excessive mucus secretion is suppressed which as a result lowers the phlegm viscosity.Formula:C13H18Br2N2O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:414.56 g/molTraxoprodil
CAS:Controlled ProductNMDA glutamate receptor antagonist; anti-depressant
Formula:C20H25NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:327.42 g/molNifedipine - Bio-X ™
CAS:Nifedipine is a dihydropyridine calcium channel blocker that is used to manage several subtypes of angina pectoris and hypertension. This drug blocks L-type voltage gated calcium channels in order for blood pressure to be reduced and an increase in oxygen supply to the heart.Formula:C17H18N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:346.33 g/molDronedarone HCl - Bio-X ™
CAS:Dronedarone is a novel class III anti-arrhythmic drug. It has been shown to be effective in the treatment of atrial fibrillation and congestive heart failure. Dronedarone is a multi-channel blocker that achieves heart rate and rhythm control in atrial fibrillation. Additonally, Dronedarone decreases arterial blood pressure and reduces oxygen consumption. It inhibits sodium currents rate-dependently and blocks slow calcium inward currents.Formula:C31H44N2O5S•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:593.22 g/molPF 06372865
CAS:Positive allosteric modulator of GABA(A) receptorFormula:C22H21FN4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:440.49 g/molAmantadine hydrochloride - Bio-X ™
CAS:Controlled ProductAmantadine is an antiviral drug that is used to treat dyskinesia in patients with Parkinson’s disease. This drug’s mechanism is not fully understood however it is said to aid in releasing dopamine from the nerve ending in brain cells. Amantadine is also an NDMA antagonist.Formula:C10H17N•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:187.71 g/molIsradipine
CAS:L-type calcium channel blockerFormula:C19H21N3O5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:371.39 g/molIcilin - Bio-X ™
CAS:Icilin is a transient receptor potential M8 (TRPM8) agonist drug that is used for the treatment of pruritis. This drug has shown to be effective in producing an extreme cold sensation in both human and animal models. It is used in research for studying TRP channels.Formula:C16H13N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:311.29 g/molPrilocaine HCl - Bio-X ™
CAS:Prilocaine is a drug used as a local anaesthetic in dental procedures. It has been shown to reduce the incidence of pain caused. This drug is also a sodium channel blocker that blocks the influx of sodium into cells.Formula:C13H20N2O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:256.77 g/molRepaglinide - Bio-X ™
CAS:Repaglinide is an antihyperglycemic drug that is used for the improvement of glycemic control in diabetes. This drug acts on the beta cells of the pancreas and binds to specific receptors on the beta cells known as ATP-sensitive potassium channels. As a result, this promotes insulin secretion from beta cells.Formula:C27H36N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:452.59 g/molVinpocetin - Bio-X ™
CAS:Vinpocetin or Vinpocetine is a synthetic derivative of a vinca alkaloid that is used to treat symptoms of cerebrovascular diseases such as stroke and dementia. It blocks sodium channels, reduces cellular calcium influx and has shown to have antioxidant activity. Studies have also suggested that vinpocetin can inhibit phosphodiesterase- 1 (PDE-1) in isolated rabbit aorta.
Formula:C22H26N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:350.45 g/molIvacaftor
CAS:Activates CFTR channelsFormula:C24H28N2O3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:392.49 g/molCytisine - Bio-X ™
CAS:Cytisine is an alkaloid found in plants derived from the Fabaceae family. It has partial agonist activity at the α4β2 nicotinic acetylcholine receptor used to aid smoking cessation. Recent studies have shown it to be a more effective smoking cessation treatment than nicotine replacement therapy.
Formula:C11H14N2OPurity:Min. 95%Color and Shape:PowderMolecular weight:190.24 g/molRiluzole - Bio-X ™
CAS:Riluzole is a glutamate antagonist that is used for the treatment of amyotrophic lateral sclerosis. This drug is also used as an anticonvulsant. Although a complete mechanism of action is unknown, it has an inhibitory effect on glutamate release and it inactivates voltage dependent sodium channels.
Formula:C8H5F3N2OSPurity:Min. 95%Color and Shape:PowderMolecular weight:234.2 g/molSuzetrigine
CAS:Suzetrigine is a novel compound classified as a synthetic ligand, which is derived through advanced chemical synthesis techniques. This compound engages specific targets within biological systems, acting primarily as a selective modulator of ion channels.
Formula:C21H20F5N3O4Molecular weight:473.39 g/molDoxapram hydrochloride
CAS:Inhibitor of TASK tandem pore potassium channel; respiratory stimulantFormula:C24H30N2O2·HClPurity:Min. 95%Noopept
CAS:Inhibitor of voltage-activated calcium channelsFormula:C17H22N2O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:318.37 g/mol
