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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 2121 products of "Angiogenesis"

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  • BI-3663

    CAS:
    <p>BI-3663 is a selective PTK2/FAK PROTAC with cereblon ligands, degrading PTK2 (IC50: 18 nM), and shows anti-cancer properties.</p>
    Formula:C44H42F3N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:917.84
  • Lestaurtinib

    CAS:
    Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.
    Formula:C26H21N3O4
    Purity:99.17%
    Color and Shape:Off-White Solid
    Molecular weight:439.46
  • SU14813 maleate

    CAS:
    SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).
    Formula:C27H31FN4O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:558.56
  • GMB-475

    CAS:
    GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.
    Formula:C43H46F3N7O7S
    Purity:98.78% - >99.99%
    Color and Shape:Solid
    Molecular weight:861.93
  • Gefitinib-based PROTAC 3

    CAS:
    Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).
    Formula:C47H57ClFN7O8S
    Purity:97.29% - 98.25%
    Color and Shape:Solid
    Molecular weight:934.51
  • AZ-5104

    CAS:
    AZ5104 is a potent EGFR inhibitor.
    Formula:C27H31N7O2
    Purity:98.40% - 99.59%
    Color and Shape:Solid Powder
    Molecular weight:485.58
  • Cediranib

    CAS:
    Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.
    Formula:C25H27FN4O3
    Purity:97.21% - 99.94%
    Color and Shape:Solid
    Molecular weight:450.51
  • AMP-945

    CAS:
    AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.
    Formula:C28H32F3N5O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:527.58
  • Ki20227

    CAS:
    Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).
    Formula:C24H24N4O5S
    Purity:98.97% - 99.88%
    Color and Shape:Solid
    Molecular weight:480.54
  • N-piperidine Ibrutinib

    CAS:
    <p>N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.</p>
    Formula:C22H22N6O
    Purity:96.65%
    Color and Shape:Solid
    Molecular weight:386.45
  • CUDC-101

    CAS:
    CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.
    Formula:C24H26N4O4
    Purity:95.76% - 99.17%
    Color and Shape:Solid
    Molecular weight:434.49
  • Theliatinib tartrate

    CAS:
    Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.
    Formula:C29H32N6O8
    Color and Shape:Solid
    Molecular weight:592.6
  • PND-1186

    CAS:
    PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
    Formula:C25H26F3N5O3
    Purity:99.14% - 99.75%
    Color and Shape:Solid
    Molecular weight:501.5
  • CCT241736

    CAS:
    CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3
    Formula:C22H23Cl2N7
    Purity:96.2% - 99.81%
    Color and Shape:Solid
    Molecular weight:456.37
  • Amuvatinib

    CAS:
    Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
    Formula:C23H21N5O3S
    Purity:99.38% - >99.99%
    Color and Shape:Solid
    Molecular weight:447.51
  • Pamufetinib mesylate

    CAS:
    Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.
    Formula:C28H27FN4O7S2
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:614.67
  • Dasatinib N-oxide

    CAS:
    <p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>
    Formula:C22H26ClN7O3S
    Purity:98.54% - 99.94%
    Color and Shape:Solid
    Molecular weight:504
  • UF010

    CAS:
    UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.
    Formula:C11H15BrN2O
    Purity:98.03% - 99.68%
    Color and Shape:Solid
    Molecular weight:271.15
  • (Z)-LFM-A13

    CAS:
    (Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.
    Formula:C11H8Br2N2O2
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:360
  • Tyrphostin A1

    CAS:
    Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
    Formula:C11H8N2O
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:184.19