Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(159 products)
- Bcr-Abl(115 products)
- EGFR(594 products)
- FAK(72 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(182 products)
- JAK(246 products)
- PDGFR(126 products)
- RAAS(90 products)
- Src(81 products)
- Syk(37 products)
- Thrombin(53 products)
- VDA(2 products)
- VEGFR(249 products)
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Found 2092 products of "Angiogenesis"
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AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purity:98.6% - 99.85%Color and Shape:Yellow SolidMolecular weight:294.3Olverembatinib dimesylate
CAS:Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formula:C29H27F3N6O·2CH4O3SPurity:97.66% - >99.99%Color and Shape:SolidMolecular weight:724.772,4-DPD
CAS:<p>2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)</p>Formula:C11H13NO4Purity:99.74%Color and Shape:Yellow Solid CrystallineMolecular weight:223.23SU6656
CAS:SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.Formula:C19H21N3O3SPurity:98.21% - 98.73%Color and Shape:SolidMolecular weight:371.45Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:266.29Afatinib oxalate
CAS:Afatinib oxalate (BIBW 2992) is an irreversible ErbB inhibitor, treating ESCC, NSCLC, and gastric cancer. Targets EGFRwt, EGFRL858R/T790M, HER2.Formula:C28H29ClFN5O11Color and Shape:SolidMolecular weight:666.01VEGFR2-IN-2
CAS:VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Formula:C15H11BrN2OPurity:99.504%Color and Shape:SolidMolecular weight:315.16Saracatinib difumarate
CAS:Saracatinib difumarate is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities.Formula:C35H40ClN5O13Color and Shape:SolidMolecular weight:774.18Acriflavine Hydrochloride
CAS:Acriflavine HCl is a HIF-1α inhibitor reducing PGK1, VEGF, and HIF-1α levels both in vitro and in vivo.Formula:C14H14ClN3Purity:99.8%Color and Shape:SolidMolecular weight:259.73Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purity:99.52%Color and Shape:SolidMolecular weight:346.81NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formula:C24H27ClN4O3Color and Shape:SolidMolecular weight:454.95Oritinib mesylate
CAS:Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.Formula:C32H41N7O5SColor and Shape:SolidMolecular weight:635.78Vatalanib succinate
CAS:Vatalanib succinate is a VEGFR, PDGFR-β, c-Kit, c-Fms, and aromatase inhibitor.Formula:C24H21ClN4O4Color and Shape:SolidMolecular weight:464.91URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purity:99.32% - 99.98%Color and Shape:SolidMolecular weight:421.54Vadimezan
CAS:Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity.Formula:C17H14O4Purity:97.38% - 99.8%Color and Shape:SolidMolecular weight:282.29JCN037
CAS:JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Formula:C16H11BrFN3O2Purity:99.5%Color and Shape:SolidMolecular weight:376.18Vandetanib hydrochloride
CAS:Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).Formula:C22H25BrClFN4O2Color and Shape:SolidMolecular weight:511.81CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purity:99.68%Color and Shape:White To Off-White SolidMolecular weight:294.3Pamufetinib mesylate
CAS:Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.Formula:C28H27FN4O7S2Purity:98.91%Color and Shape:SolidMolecular weight:614.67XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54
