Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(159 products)
- Bcr-Abl(115 products)
- EGFR(594 products)
- FAK(72 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(182 products)
- JAK(246 products)
- PDGFR(126 products)
- RAAS(90 products)
- Src(81 products)
- Syk(37 products)
- Thrombin(53 products)
- VDA(2 products)
- VEGFR(249 products)
Show 6 more subcategories
Found 2092 products of "Angiogenesis"
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CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purity:99.35% - 99.88%Color and Shape:SolidMolecular weight:491.5Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formula:C22H19ClN4O5Purity:98.08% - 99.67%Color and Shape:SolidMolecular weight:454.86Ritlecitinib tosylate
CAS:Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.Formula:C22H27N5O4SColor and Shape:SolidMolecular weight:457.549Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:468.47JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurity:99.43% - 99.98%Color and Shape:SolidMolecular weight:649.76Almonertinib mesylate
CAS:Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.Formula:C31H39N7O5SPurity:99.92%Color and Shape:SolidMolecular weight:621.75Tandutinib hydrochloride
CAS:Tandutinib hydrochloride: FLT3 inhibitor (IC50 0.22 μM), targets c-Kit, PDGFR, treats AML, crosses blood-brain barrier.Formula:C31H43ClN6O4Color and Shape:SolidMolecular weight:599.16ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purity:99.11% - 99.59%Color and Shape:Pale Yellow SolidMolecular weight:513.59(S)-Afatinib
CAS:(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formula:C24H25ClFN5O3Purity:99.22% - >99.99%Color and Shape:Off-White SolidMolecular weight:485.94CHIR-124
CAS:CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.Formula:C23H22ClN5OPurity:96.33% - 98.35%Color and Shape:SolidMolecular weight:419.91Nazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Formula:C26H31ClN6O2Purity:98.63% - ≥95%Color and Shape:Solid PowderMolecular weight:495.02CEP-28122 mesylate salt
<p>CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.</p>Formula:C29H39ClN6O6SColor and Shape:SolidMolecular weight:635.17Vandetanib trifluoroacetate
CAS:Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).Formula:C24H25BrF4N4O4Color and Shape:SolidMolecular weight:589.386URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purity:99.32% - 99.98%Color and Shape:SolidMolecular weight:421.54EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:98.99% - >99.99%Color and Shape:SolidMolecular weight:430.55Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purity:98.53%Color and Shape:Yellow PowderMolecular weight:193.16Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurity:98.73% - 98.87%Color and Shape:SolidMolecular weight:486.8MELK-8a
CAS:MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formula:C25H32N6OColor and Shape:SolidMolecular weight:432.56
