Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(159 products)
- Bcr-Abl(115 products)
- EGFR(593 products)
- FAK(72 products)
- FLT(89 products)
- Fibroblast Growth Factor Receptor (FGFR)(182 products)
- JAK(246 products)
- PDGFR(126 products)
- RAAS(90 products)
- Src(81 products)
- Syk(37 products)
- Thrombin(53 products)
- VDA(2 products)
- VEGFR(247 products)
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Found 2121 products of "Angiogenesis"
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Naluzotan
CAS:Naluzotan（PRX 00023） is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+Formula:C23H38N4O3SPurity:>99.99%Color and Shape:SolidMolecular weight:450.64EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formula:C21H18F3N5OPurity:98.3% - 99.76%Color and Shape:SolidMolecular weight:413.4HA 155
CAS:HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.Formula:C24H19BFNO5SPurity:99.88%Color and Shape:SolidMolecular weight:463.29Filgotinib maleate
CAS:Filgotinib maleate, a selective oral JAK1 inhibitor, treats RA and Crohn's. IC50s: JAK1-10nM, JAK2-28nM, JAK3-810nM, TYK2-116nM.Formula:C25H27N5O7SColor and Shape:SolidMolecular weight:541.58Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82Mobocertinib
CAS:Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agentFormula:C32H39N7O4Purity:99.47% - 99.97%Color and Shape:SolidMolecular weight:585.7KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Formula:C30H37ClN8O4Purity:96.19%Color and Shape:SolidMolecular weight:609.12PKI-166 hydrochloride
CAS:EGFR-kinase inhibitor, IC50 0.7 nM, >3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.Formula:C20H19ClN4OColor and Shape:SolidMolecular weight:366.85N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS:Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.Formula:C22H18BrN7Purity:99.935%Color and Shape:SolidMolecular weight:460.33Pamufetinib mesylate
CAS:Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.Formula:C28H27FN4O7S2Purity:98.91%Color and Shape:SolidMolecular weight:614.67Epitinib
CAS:<p>Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).</p>Formula:C24H26N6O2Color and Shape:SolidMolecular weight:430.5BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purity:97.71% - 99.89%Color and Shape:SolidMolecular weight:439.39ASP5878
CAS:ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.Formula:C18H19F2N5O4Purity:99.8% - 99.89%Color and Shape:SolidMolecular weight:407.37VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formula:C19H24N8Purity:99.92%Color and Shape:SolidMolecular weight:364.45TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurity:99.28% - 99.82%Color and Shape:SolidMolecular weight:380.85PF-562271
CAS:PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formula:C21H20F3N7O3SPurity:97.17% - >99.99%Color and Shape:SolidMolecular weight:507.49G-749
CAS:G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.Formula:C25H25BrN6O2Purity:98.32% - 99.60%Color and Shape:SolidMolecular weight:521.41CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46SB1317 hydrochloride (1204918-72-8(free base))
SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).Formula:C23H25ClN4OPurity:99.84%Color and Shape:SolidMolecular weight:408.92ALK kinase inhibitor-1
CAS:SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.Formula:C28H32FN5O3SPurity:99.84%Color and Shape:SolidMolecular weight:537.65
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