CymitQuimica logo
Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

Show 6 more subcategories

Found 1522 products of "Angiogenesis"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • CymitQuimica logo
    Targetmol
    + Info

    EGFR-IN-48

    <p>EGFR-IN-48: potent EGFR inhibitor, oral, IC50: 0.193-66.7 nM, blocks EGFR mutants &amp; BaF3/PC-9 cell proliferation.</p>
    Color and Shape:Solid

    Ref: TM-T64255

  • CymitQuimica logo
    Targetmol
    + Info

    VEGFR-2-IN-16

    <p>VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects.</p>
    Formula:C21H13Cl2N3O2
    Color and Shape:Solid
    Molecular weight:410.25

    Ref: TM-T62071

  • EGFR-IN-23
    Targetmol
    + Info

    EGFR-IN-23

    CAS:
    <p>EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.</p>
    Formula:C36H44BrN10O3P
    Color and Shape:Solid
    Molecular weight:775.68

    Ref: TM-T73104

  • HSN748
    Targetmol
    + Info

    HSN748

    CAS:
    <p>HSN748 is an analog of ponatinib and acts as a multi-kinase inhibitor. It exhibits inhibitory activity against kinases such as FLT3, ABL1, RET, PDGFRα/β, MNK1, and MNK2. HSN748 can suppress the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines, making it a useful compound in leukemia research.</p>
    Formula:C27H24F3N7O
    Color and Shape:Solid
    Molecular weight:519.521

    Ref: TM-T204396

  • CymitQuimica logo
    Targetmol
    + Info

    EGFR-IN-24

    <p>EGFR-IN-24 is a potent inhibitor of EGFR and inhibits EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S).</p>
    Formula:C30H35FN6O3
    Color and Shape:Solid
    Molecular weight:546.64

    Ref: TM-T63857

  • Multi-kinase-IN-1
    Targetmol
    + Info

    Multi-kinase-IN-1

    CAS:
    <p>Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis.</p>
    Formula:C35H36F2N6O6S
    Color and Shape:Solid
    Molecular weight:706.76

    Ref: TM-T72604

  • JNJ-47117096
    Targetmol
    + Info

    JNJ-47117096

    CAS:
    <p>JNJ-47117096 is a potent and selective MELK inhibitor with an IC50 of 23 nM, and it also exhibits strong activity against Flt3 with an IC50 of 18 nM.</p>
    Formula:C21H22N4O2
    Color and Shape:Solid
    Molecular weight:362.425

    Ref: TM-T204607

  • CymitQuimica logo
    Targetmol
    + Info

    HER2-IN-9

    <p>HER2-IN-9, an oral HER2 inhibitor (IC50: 0.03 μM), hinders growth and spread of HER2+ breast cancer.</p>
    Formula:C19H14BrF3N2O
    Color and Shape:Solid
    Molecular weight:423.23

    Ref: TM-T62271

  • VEGFR/PDGFR-IN-1
    Targetmol
    + Info

    VEGFR/PDGFR-IN-1

    CAS:
    VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.
    Formula:C17H21N5O3
    Color and Shape:Solid
    Molecular weight:343.38

    Ref: TM-T205236

  • CymitQuimica logo
    Targetmol
    + Info

    BTK-IN-7

    <p>BTK-IN-7 is a potent inhibitor for BTK with 4.0 nM IC50, highly selective over ITK and EGFR, showing strong antitumor activity.</p>
    Formula:C30H32N6O4
    Color and Shape:Solid
    Molecular weight:540.61

    Ref: TM-T63810

  • LSD1/EGFR-IN-1
    Targetmol
    + Info

    LSD1/EGFR-IN-1

    CAS:
    <p>LSD1/EGFR-IN-1 (compound L-1) is an effective inhibitor of LSD1, EGFRT790M/L858R, and EGFRL858R/T790M/C797S, with IC50 values of 6.24, 2.06, and 5.01 μM, respectively. This compound plays a significant role in cancer research.</p>
    Formula:C21H20ClN3O4
    Color and Shape:Solid
    Molecular weight:413.854

    Ref: TM-T204471

  • CymitQuimica logo
    Targetmol
    + Info

    EGFR/HER2-IN-6

    <p>EGFR/HER2-IN-6 is a dual inhibitor of EGFR, HER2, and DHFR with IC50s: 0.122, 0.078, and 0.585 μM, showing anticancer potential and selectivity.</p>
    Formula:C18H21N5O3S
    Color and Shape:Solid
    Molecular weight:387.46

    Ref: TM-T61732

  • HER2-IN-21
    Targetmol
    + Info

    HER2-IN-21

    CAS:
    <p>HER2-IN-21 (compound 657994) is an inhibitor of the human epidermal growth factor receptor 2 (HER2) with an IC50 value of 3.85 μM.</p>
    Formula:C20H18N4O3S
    Color and Shape:Solid
    Molecular weight:394.447

    Ref: TM-T205331

  • CymitQuimica logo
    Targetmol
    + Info

    FGFR4-IN-6

    <p>FGFR4-IN-6: covalent, reversible FGFR4 blocker, 5.4 nM IC50, good oral bioavailability, reduces Hep3B2.1-7 tumors in mice, low toxicity.</p>
    Formula:C31H33N7O4
    Color and Shape:Solid
    Molecular weight:567.64

    Ref: TM-T64015

  • Protein kinase inhibitor 10
    Targetmol
    + Info

    Protein kinase inhibitor 10

    CAS:
    <p>Protein kinase inhibitor 10 is a protein kinase inhibitor with IC50 values of 28.9 μM, 13.6 μM, and 2.41 μM for TAM receptors, FAK, and KIT, respectively. It can inhibit abnormal and excessive cell proliferation, showing potential for research in the field of cancer treatment.</p>
    Formula:C14H9FN6S2
    Color and Shape:Solid
    Molecular weight:344.39

    Ref: TM-T205111

  • VEGFR-2-IN-26
    Targetmol
    + Info

    VEGFR-2-IN-26

    CAS:
    <p>VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.</p>
    Formula:C24H19F3N6O2
    Color and Shape:Solid
    Molecular weight:480.44

    Ref: TM-T63168

  • CymitQuimica logo
    Targetmol
    + Info

    FGFR4-IN-9

    <p>FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.</p>
    Formula:C24H22ClF3N4O4
    Color and Shape:Solid
    Molecular weight:522.9

    Ref: TM-T63662

  • PF-06263276
    Targetmol
    + Info

    PF-06263276

    CAS:
    <p>PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).</p>
    Formula:C31H31FN8O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:566.63

    Ref: TM-T16488

  • EGFR-IN-161
    Targetmol
    + Info

    EGFR-IN-161

    CAS:
    <p>EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of the L858R/T790M/C797S mutant EGFR kinase, with an IC50 value of 0.87 nM. EGFR-IN-161 effectively inhibits tumor cell apoptosis, G1 phase arrest, and migration.</p>
    Formula:C33H36Cl2N8O2
    Color and Shape:Solid
    Molecular weight:647.597

    Ref: TM-T206760

  • Dual Cathepsin L/JAK-IN-1
    Targetmol
    + Info

    Dual Cathepsin L/JAK-IN-1

    CAS:
    <p>DualCathepsinL/JAK-IN-1 (Compound A8) serves as a dual inhibitor of Cathepsin L (CTSL) and JAK, exhibiting IC50 values of 0.68 μM for CTSL and 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for JAK1/2/3 and TYK2, respectively. This compound effectively prevents the activation of MAPK, NF-κB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. DualCathepsinL/JAK-IN-1 is applicable in research on acute lung injury (ALI).</p>
    Formula:C19H18ClN5
    Color and Shape:Solid
    Molecular weight:351.833

    Ref: TM-T205041