Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(167 products)
- Bcr-Abl(118 products)
- EGFR(581 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2382 products of "Angiogenesis"
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T338C Src-IN-2
CAS:T338C Src-IN-2: Potent c-Src T338C kinase inhibitor; IC50: 317 nM, T338C/V323A: 57 nM, T338C/V323S: 19 nM.Formula:C17H18FN5OPurity:98%Color and Shape:SolidMolecular weight:327.36TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Formula:C19H19N3O4SColor and Shape:SolidMolecular weight:385.44EGFR-IN-67
CAS:EGFR-IN-67 (Compound 7d) is a potent inhibitor of EGFR with anticancer activity (IC 50 = 0.34 μM) [1].Formula:C18H17N3SColor and Shape:SolidMolecular weight:307.41Squarunkin A hydrochloride
CAS:Squarunkin A HCl inhibits UNC119-cargo binding, specifically blocks Src kinase activation, IC50=10 nm.Formula:C25H33ClF3N5O4Color and Shape:SoildMolecular weight:560.02JAK-2/3-IN-2
CAS:JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).Formula:C19H19ClN2OSColor and Shape:SolidMolecular weight:358.89JNJ-47117096 hydrochloride
CAS:JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.Formula:C21H23ClN4O2Color and Shape:SolidMolecular weight:398.89c-ABL-IN-2
CAS:C-ABL-IN-2 is a potent c-Abl protein inhibitor, promising for research in cancer and neurodegenerative diseases like ALS and PD.Formula:C21H20N4OColor and Shape:SolidMolecular weight:344.41MS 154N
CAS:MS 154N is a negative control for MS 154, binds WT/L858R EGFR tightly (Kd 3-4.3nM), doesn't trigger mutant EGFR degradation.Formula:C47H56ClFN8O8Color and Shape:SolidMolecular weight:915.45Esuberaprost Sodium
CAS:Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.Formula:C23H27FN4O2Color and Shape:SolidMolecular weight:410.48OD36 hydrochloride
CAS:OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficientlyFormula:C16H16Cl2N4O2Purity:99.85%Color and Shape:SolidMolecular weight:367.23TYK2-IN-12
CAS:TYK2-IN-12: selective oral TYK2 inhibitor (Ki: 0.51 nM), blocks IL-12-induced IFNγ; IC50: human 2.7 µM, mouse 7.0 µM, used for psoriasis research.Formula:C24H20F2N4O2Color and Shape:SolidMolecular weight:434.44PDE5-IN-3
CAS:PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.Formula:C21H14BrN5O2Color and Shape:SolidMolecular weight:448.27PDGFR-IN-1
CAS:PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formula:C25H30N8OPurity:99.13% - 99.49%Color and Shape:SolidMolecular weight:458.56Ref: TM-T62872
1mg170.00€5mg432.00€10mg655.00€25mg1,153.00€50mg1,665.00€100mg2,250.00€1mL*10mM (DMSO)434.00€IHMT-TRK-284
CAS:IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formula:C25H27N7OSColor and Shape:SolidMolecular weight:473.59FGFR3-IN-2
CAS:FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor that inhibits FGFR3 (IC50: 4.1 nM) and VEGFR2 (IC50: 570 nM).Formula:C28H39N9O4SColor and Shape:SolidMolecular weight:597.73CpCDPK1/TgCDPK1-IN-1
CAS:CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.Formula:C18H17N5Purity:99.61%Color and Shape:SolidMolecular weight:303.36AG-370
CAS:AG 370, an indole tyrphostin, functions as a powerful inhibitor of PDGF-induced mitogenesis, demonstrating an IC50 of 20 μM.Formula:C15H9N5Color and Shape:SolidMolecular weight:259.27ALK-IN-22
CAS:ALK-IN-22 suppresses ALK and mutants (IC50: 2.3-3.7 nM), hinders phosphorylation, and induces apoptosis in tumor studies.Formula:C24H24ClN7O2Color and Shape:SolidMolecular weight:477.95RIPK2-IN-1
CAS:RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 (IC50: 51 nM) and also inhibits ALK2 (IC50: 5 nM).Formula:C23H27N5O3SColor and Shape:SolidMolecular weight:453.56EGFR-IN-59
CAS:EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.Formula:C27H23N5O4SColor and Shape:SolidMolecular weight:513.57RET-IN-19
CAS:RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.Formula:C28H28N6O4SColor and Shape:SolidMolecular weight:544.62TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formula:C16H18N6OPurity:98%Color and Shape:SolidMolecular weight:310.35VA5 TG2 inhibitor
CAS:VA5 inhibits transamidase and GTP-binding by locking protein in an open state, disabling GTPase.Formula:C31H34N4O8Purity:98%Color and Shape:SolidMolecular weight:590.62ARQ 069
CAS:ARQ 069 inhibits FGFR2 phosphorylation concentration-dependently (IC50: 9.7 µM), without affecting β-actin. Preferentially binds inactive FGFR1/2.Formula:C18H15N3Purity:98%Color and Shape:SolidMolecular weight:273.33JTV-519 free base
CAS:JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmicFormula:C25H32N2O2SPurity:98%Color and Shape:SolidMolecular weight:424.6EGFR-IN-46
CAS:EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.Formula:C27H32F3N3O3Color and Shape:SolidMolecular weight:503.56Y 11
CAS:focal adhesion kinase (FAK) inhibitorFormula:C8H17BrN4OPurity:98%Color and Shape:SolidMolecular weight:265.15FLT3-IN-6
CAS:FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.Formula:C23H25N5O3Color and Shape:SolidMolecular weight:419.48CGI560
CAS:CGI560 is a potent BTK inhibitor with IC50 = 400 nM for BTK.Formula:C29H27N5OColor and Shape:SolidMolecular weight:461.56MBM-55S
CAS:MBM-55S, a Nek2 inhibitor with 1 nM IC50, induces cell cycle arrest and apoptosis, suppressing tumor growth.Formula:C36H39FN6O10Purity:99.37% - 99.89%Color and Shape:SolidMolecular weight:734.73Ref: TM-T11961
1mg185.00€2mg279.00€5mg426.00€10mg627.00€25mg938.00€50mg1,320.00€100mg1,786.00€500mg3,591.00€1mL*10mM (DMSO)630.00€BMS-243117
CAS:BMS-243117: Selective LCK inhibitor, IC50=1.1µM, inhibits T cell growth, promising for immunosuppression, arthritis, asthma treatment.Formula:C20H21ClN4O2SColor and Shape:SolidMolecular weight:416.92BTK-IN-9
CAS:BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.Formula:C25H19N7O4Color and Shape:SolidMolecular weight:481.46JAK-IN-14
CAS:JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.Formula:C19H15FN4OPurity:98.27%Color and Shape:SolidMolecular weight:334.35Ref: TM-T9764
1mg81.00€5mg170.00€10mg268.00€25mg555.00€50mg888.00€100mg1,414.00€200mg1,882.00€1mL*10mM (DMSO)178.00€JAK-IN-18
CAS:"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."Formula:C27H28F2N6O3Color and Shape:SolidMolecular weight:522.55HZ-A-005
CAS:HZ-A-005 is a selective, potent, covalent inhibitor of Bruton's tyrosine kinase (BTK). HZ-A-005 significantly inhibits tumour growth in a xenograft mouse model.Formula:C25H23ClN6O2Color and Shape:SolidMolecular weight:474.94ALK-IN-21
CAS:ALK-IN-21 (B10) inhibits ALK WT (IC50: 4.59nM), L1196M (2.07nM), G1202R (5.95nM); curbs Karpas299, H2228 cell growth; for ALCL research.Formula:C35H45ClN6O6S4Color and Shape:SolidMolecular weight:809.48Tyrphostin 51
CAS:Tyrphostin 51 is an effective inhibitor of EGFR kinase.Formula:C13H8N4O3Purity:98%Color and Shape:SolidMolecular weight:268.23GDC-0834 S-enantiomer
CAS:GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).Formula:C33H36N6O3SPurity:98%Color and Shape:SolidMolecular weight:596.74Atopaxar
CAS:Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H38FN3O5Purity:97.07% - 98.07%Color and Shape:SolidMolecular weight:527.63JNJ28871063 hydrochloride
CAS:ErbB receptor family inhibitorFormula:C24H28Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:519.42AAE871
CAS:AAE871 is a type I FLT3 inhibitor.Formula:C24H34N8O2SColor and Shape:SolidMolecular weight:498.64pan-HER-IN-1
CAS:Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.Formula:C19H14BrN5OColor and Shape:SolidMolecular weight:408.25Nuvenzepine
CAS:Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.Formula:C19H20N4O2Purity:98%Color and Shape:SolidMolecular weight:336.39HS-438
CAS:HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.Formula:C17H17N3O3SColor and Shape:SolidMolecular weight:343.4EL-102
CAS:EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.Formula:C19H16N2O3S2Purity:99.34%Color and Shape:SolidMolecular weight:384.47Ref: TM-T15205
1mg93.00€5mg205.00€10mg331.00€25mg515.00€50mg700.00€100mg1,044.00€1mL*10mM (DMSO)173.00€Sch 13835
CAS:Sch 13835 is an inhibitor of platelet derived growth factor.Formula:C15H10ClNO4SPurity:98%Color and Shape:SolidMolecular weight:335.76EGFR-IN-64
CAS:EGFR-IN-64 inhibits EGFR with 0.33 μM IC50, showing promising anticancer properties.Formula:C20H21N3O3Color and Shape:SolidMolecular weight:351.4Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54TG 100801 Hydrochloride
CAS:TG 100801: prodrug for macular degeneration. TG 100572: inhibits kinases (VEGFRs, FGFRs, PDGFRβ, Src family), with varying IC50s.Formula:C33H31Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:616.54MAX-40279 hemifumarate
CAS:MAX-40279 hemifumarate inhibits FLT3 and FGFR kinases, showing promise for AML treatment.Formula:C48H50F2N12O6S2Color and Shape:SolidMolecular weight:993.12
