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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 1431 products of "Angiogenesis"

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  • EGFR-IN-71

    CAS:
    <p>EGFR-IN-71 is a potent inhibitor of epidermal growth factor receptor (EGFR) (IC50= 3.7 μM). EGFR-IN-71 has research value in chordoma.</p>
    Formula:C16H9ClIN3
    Color and Shape:Solid
    Molecular weight:405.62
  • 10Z-Hymenialdisine

    CAS:
    <p>Pan kinase inhibitor</p>
    Formula:C11H10BrN5O2
    Purity:98%
    Color and Shape:Light Yellow Solid
    Molecular weight:324.13
  • FGFR-IN-8

    CAS:
    <p>FGFR-IN-8, potent oral FGFR inhibitor for wild-type/mutant types, induces apoptosis with anti-cancer properties.</p>
    Formula:C27H31Cl2N9O2
    Color and Shape:Solid
    Molecular weight:584.5
  • Henatinib

    CAS:
    <p>Henatinib: orally active multi-kinase inhibitor targeting VEGFR-2, c-kit, PDGFR with antitumor effects.</p>
    Formula:C25H29FN4O4
    Color and Shape:Solid
    Molecular weight:468.52
  • CHMFL-FLT3-122

    CAS:
    <p>CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor used to treat FLT3-ITD positive acute myeloid leukemia.</p>
    Formula:C26H29N7O2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:471.55
  • MS 154

    CAS:
    <p>MS 154 is a potent PROTAC® targeting mutant EGFR in lung cancer, sparing WT-EGFR; effective in mice, with DC50 of 11-25 nM.</p>
    Formula:C46H54ClFN8O8
    Color and Shape:Solid
    Molecular weight:901.42
  • EGFR-IN-33

    CAS:
    <p>EGFR-IN-33, a low-toxicity acrylamide, inhibits EGFR, aiding against cancer, especially NSCLC (from WO2021185348A1, comp. 13).</p>
    Formula:C26H25ClN6O2
    Color and Shape:Solid
    Molecular weight:488.97
  • GSK2646264

    CAS:
    <p>GSK2646264 (Compound 44) inhibits SYK (pIC50=7.1) and kinases like LCK, LRRK2; penetrates skin.</p>
    Formula:C24H26N2O2
    Color and Shape:Solid
    Molecular weight:374.48
  • Larixol

    CAS:
    <p>Larixol acts as both an fMLP inhibitor and a modulator of various signaling pathways by inhibiting Src kinase, ERK1/2, p38, and AKT phosphorylation critical for</p>
    Formula:C20H34O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:306.48
  • PF-06459988

    CAS:
    <p>PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.</p>
    Formula:C19H22ClN7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:431.88
  • Sevabertinib

    CAS:
    <p>Sevabertinib (BAY 2927088) is an EGFR tyrosine kinase inhibitor, with anticancer activity, used in research on non-small cell lung cancer.</p>
    Formula:C24H25ClN4O5
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:484.93
  • KER047

    CAS:
    <p>ALK2-IN-4, a highly effective ALK2 inhibitor.</p>
    Formula:C26H30FN7O
    Purity:98.49% - >99.99%
    Color and Shape:Solid
    Molecular weight:475.56
  • IN-1130

    CAS:
    <p>IN-1130: ALK5 inhibitor, IC50 - 5.3 nM (Smad3), 36 nM (casein), 4.3 μM (p38α MAPK).</p>
    Formula:C25H20N6O
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:420.47
  • BMS-935177

    CAS:
    <p>BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.</p>
    Formula:C31H26N4O3
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:502.56
  • EGFR-IN-87

    CAS:
    EGFR-IN-87 is an EGFR tyrosine kinase inhibitor with potent inhibitory activity, exhibiting IC50 values of 3.1 nM, 1.3 nM, and 7.1 nM against EGFR_d746-750,
    Formula:C28H33N7O2
    Purity:98.64%
    Color and Shape:Solid
    Molecular weight:499.61
  • Zongertinib

    CAS:
    <p>Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective for covalent binding to the HER2 tyrosine kinase domain (</p>
    Formula:C29H29N9O2
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:535.6
  • HM43239

    CAS:
    <p>HM43239: oral FLT3 inhibitor; IC50: FLT3 WT 1.1nM, ITD 1.8nM, D835Y 1.0nM; blocks p-STAT5/p-ERK; affects SYK, JAK1/2, TAK1; halts leukemia cell growth.</p>
    Formula:C29H33ClN6
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:501.07
  • HDHD4-IN-1

    CAS:
    <p>HDHD4-IN-1 (compound 3) is an inhibitor of N-acetylneuraminate-9-phosphate phosphatase (HDHD4) with an IC50 value of 11 μM. It is utilized in the research of neurological disorders.</p>
    Formula:C12H22NO11P
    Color and Shape:Solid
    Molecular weight:387.28
  • MM-589

    CAS:
    <p>MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.</p>
    Formula:C28H44N8O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:572.70
  • Lomonitinib

    CAS:
    <p>Lomonitinib is a potent and selective pan-FLT3/IRAK4 inhibitor with antitumor properties. It shows promise for research in myeloid leukemia.</p>
    Formula:C27H24N4O2
    Color and Shape:Solid
    Molecular weight:436.505