CymitQuimica logo
Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

Show 6 more subcategories

Found 1483 products of "Angiogenesis"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Apoptosis inducer 35
    Targetmol
    + Info

    Apoptosis inducer 35

    <p>Apoptosisinducer 35 (Compound 6) is a multi-target inhibitor that reduces the expression of EGFR, AKT, ERK, and P38-MAPKα. It suppresses the proliferation of cancer cells A549 and Jurkat, induces cell cycle arrest at the S phase, and triggers apoptosis (cell death).</p>
    Formula:C23H21ClN8O2S2
    Color and Shape:Solid
    Molecular weight:541.048

    Ref: TM-T204472

  • SNIPER(ABL)-039
    Targetmol
    + Info

    SNIPER(ABL)-039

    CAS:
    <p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>
    Formula:C54H68ClN11O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1114.77

    Ref: TM-T18690

  • HER2/neu (654-662) GP2
    Targetmol
    + Info

    HER2/neu (654-662) GP2

    CAS:
    <p>Phage display selected Affibody ligands for HER2/neu from a protein library based on a 58-residue Staphylococcal protein A Z domain.</p>
    Formula:C42H77N9O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:884.11

    Ref: TM-TP1583

  • JAK1/TYK2-IN-1
    Targetmol
    + Info

    JAK1/TYK2-IN-1

    CAS:
    <p>JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).</p>
    Formula:C18H20F3N7O
    Color and Shape:Solid
    Molecular weight:407.401

    Ref: TM-T39314

  • Hck-IN-2
    Targetmol
    + Info

    Hck-IN-2

    <p>Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.</p>
    Formula:C36H35FN6O10
    Color and Shape:Solid
    Molecular weight:730.696

    Ref: TM-T205715

  • PTD10
    Targetmol
    + Info

    PTD10

    CAS:
    <p>PTD10, a highly potent PROTAC BTK degrader, exhibits a DC50 of 0.5 nM and a KD of 2.28 nM.</p>
    Formula:C49H51N11O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:922

    Ref: TM-T79201

  • EGFR-IN-22
    Targetmol
    + Info

    EGFR-IN-22

    CAS:
    <p>EGFR-IN-22: potent for EGFR (IC50: 4.91 nM) &amp; L858R/T790M/C797S mutation (IC50: 0.54 nM).</p>
    Formula:C38H47BrFN10O2P
    Color and Shape:Solid
    Molecular weight:805.72

    Ref: TM-T74215

  • SNIPER(ABL)-050
    Targetmol
    + Info

    SNIPER(ABL)-050

    <p>SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.</p>
    Formula:C68H84N12O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1213.47

    Ref: TM-T18694

  • MS9427
    Targetmol
    + Info

    MS9427

    CAS:
    <p>MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.</p>
    Formula:C48H58ClFN8O12
    Color and Shape:Solid
    Molecular weight:993.47

    Ref: TM-T74633

  • KIT/PDGFRA-IN-1
    Targetmol
    + Info

    KIT/PDGFRA-IN-1

    <p>KIT/PDGFRA-IN-1 (compound 19) is an inhibitor targeting the stem cell growth factor receptor (KIT) and platelet-derived growth factor receptor alpha (PDGFRA). Its IC50 values are 2.3 µM for KIT-wt, 12 µM for KIT-D816H, 492 µM for KIT-T670I, 0.8 µM for PDGFRA-wt, 99.9 µM for PDGFRA-D842V, 42.3 µM for PDGFRA-T674I, and 4.3 µM for PDGFRA-G680R. The GR50 values for GIST-T1, T1-a-D842V, and GIST-48B cell lines (gastrointestinal stromal tumor cell lines with PDGFR and KIT mutations) are 12 nM, 8900 nM, and ≥10,000 nM, respectively.</p>
    Formula:C26H18F3N5O2
    Color and Shape:Solid
    Molecular weight:489.449

    Ref: TM-T205746

  • HIF-1 inhibitor-4
    Targetmol
    + Info

    HIF-1 inhibitor-4

    CAS:
    <p>HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM.</p>
    Formula:C18H19IN2O2
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:422.26

    Ref: TM-T67767

  • INCB-000928
    Targetmol
    + Info

    INCB-000928

    CAS:
    <p>Zilurgisertib (INCB-000928) is a selective and potent ALK 2 inhibitor for the study of cancer and MF anemia.</p>
    Formula:C30H38N4O3
    Purity:98.93%
    Color and Shape:Solid
    Molecular weight:502.65

    Ref: TM-T77726

  • HIF-1 Signaling Pathway Compound Library
    Targetmol
    + Info

    HIF-1 Signaling Pathway Compound Library

    <p>A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；</p>
    Color and Shape:Odour Solid

    Ref: TM-L8500

  • CymitQuimica logo
    Targetmol
    + Info

    FLT3/VEGFR2-IN-1

    <p>FLT3/VEGFR2-IN-1 (Compound 26) is a potent inhibitor of FLT3, VEGFR2, and HDAC, exhibiting IC50 values of 14.5 nM, 3.9 nM, and 30.8 nM against FLT3, VEGFR2, and HDAC1, respectively. It effectively inhibits the phosphorylation of STAT3 and ERK1/2, as well as the proliferation of leukemia cells. FLT3/VEGFR2-IN-1 demonstrates antitumor activity and is applicable in research on acute myeloid leukemia.</p>
    Formula:C29H35N7O5
    Color and Shape:Solid
    Molecular weight:561.63

    Ref: TM-T205440

  • CymitQuimica logo
    Targetmol
    + Info

    JAK/HDAC-IN-2

    <p>JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations.</p>
    Formula:C28H38N6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:570.7

    Ref: TM-T78708

  • cep-5214
    Targetmol
    + Info

    cep-5214

    CAS:
    <p>CEP-5214: Powerful pan VEGF-R tyrosine kinase inhibitor; IC50: 16nM (R1), 8nM (R2), 4nM (R3); effective in cells.</p>
    Formula:C28H28N2O3
    Color and Shape:Solid
    Molecular weight:440.53

    Ref: TM-T68039

  • SIAIS178
    Targetmol
    + Info

    SIAIS178

    CAS:
    <p>SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).</p>
    Formula:C50H62ClN11O6S2
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:1012.68

    Ref: TM-T12907

  • PROTAC EGFR degrader 4
    Targetmol
    + Info

    PROTAC EGFR degrader 4

    CAS:
    <p>PROTAC EGFR degrader 4 targets mutant EGFR, degrades del19 and L858R/T790M (DC50: 0.51, 126 nM), and inhibits HCC827, H1975 cell growth (IC50: 0.83, 203.1 nM).</p>
    Formula:C55H70N12O4S
    Color and Shape:Solid
    Molecular weight:995.29

    Ref: TM-T74515

  • BTK inhibitor 19
    Targetmol
    + Info

    BTK inhibitor 19

    CAS:
    <p>BTK inhibitor 19 is a highly selective, covalent BTK inhibitor ( IC 50 = 2.7 nM).</p>
    Formula:C25H24F3N7O3
    Color and Shape:Solid
    Molecular weight:527.508

    Ref: TM-T40185

  • CymitQuimica logo
    Targetmol
    + Info

    FAK-IN-27

    <p>FAK-IN-27 (compound 8A) is a potent and selective inhibitor of FAK, with an IC50 of 4.968 nM. It effectively inhibits the proliferation of H1299 cells, with an IC50 of 0.28 μM, and is applicable for research in non-small cell lung cancer (NSCLC).</p>
    Formula:C32H28ClN5O6
    Color and Shape:Solid
    Molecular weight:613.17281

    Ref: TM-T207271