EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
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EAI001
CAS:892772-75-7
EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that …
Formula:
C19H15N3O2S
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
349.41
Ref: TM-T61191
| 5mg | 56.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 454.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
ALK/EGFR-IN-1
CAS:2730430-08-5
ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their …
Formula:
C27H34ClN7O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
572.12
Ref: TM-T79392
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
HKI-357
CAS:848133-17-5
HKI-357 irreversibly inhibits EGFR/ERBB2 (IC50: 34/33 nM), blocks EGFR Y1068 autophosphorylation, and AKT/MAPK phosphorylation.
Formula:
C31H29ClFN5O3
Purity:
95.11%
Color and Shape:
Solid
Molecular weight:
574.05
Ref: TM-T11569
| 1mg | 79.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 662.00 € | ||
| 100mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
PF-06459988
CAS:1428774-45-1
PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) …
Formula:
C19H22ClN7O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
431.88
Ref: TM-T16492
| 1mg | 146.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
JND3229
CAS:2260886-64-2
JND3229 inhibits EGFRC797S; IC50: 5.8-30.5 nM; halts cell growth; effective in non-small cell lung cancer …
Formula:
C33H41ClN8O2
Purity:
97.35%
Color and Shape:
Solid
Molecular weight:
617.18
Ref: TM-T15615
| 1mg | 60.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 188.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
EGFR-IN-85
CAS:1956378-29-2
EGFR-IN-85 (Compound 1), an EGFR inhibitor, exhibits potent activity with an IC50 of 0.19 μM …
Formula:
C26H30N8O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
486.57
Ref: TM-T78574
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
EGFR-IN-61
CAS:2890261-81-9
EGFR-IN-61 inhibits EGFR kinase (IC50: 42 nM L858R/T790M, 137 nM L858R/T790M/C797S, 743 nM WT) and …
Formula:
C33H37ClN8O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
629.15
Ref: TM-T73128
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
JGK-068S
CAS:2490431-16-6
Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].
Formula:
C22H23BrFN5O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
488.35
Ref: TM-T79124
| 5mg | 1,301.00 € | ||
| 50mg | 2,642.00 € | ||
| 100mg | 3,515.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
DZD1516
CAS:2387570-00-3
DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier …
Formula:
C28H27F2N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
547.56
Ref: TM-T79297
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
2′-Thioadenosine
CAS:136904-69-3
2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, …
Formula:
C10H13N5O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
283.31
Ref: TM-T78634
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
BEBT-109
CAS:2050906-40-4
BEBT-109 is a selective epidermal growth factor receptor (EGFR) inhibitor that shows anti-tumor activity in …
Formula:
C27H32N8O3
Purity:
99.01%
Color and Shape:
Liquid
Molecular weight:
516.6
Ref: TM-T80643
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
YK-029A
CAS:2064269-82-3
YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.
Formula:
C27H32N8O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
500.6
Ref: TM-T79461
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
EGFR/ErbB-2 inhibitor-1
CAS:1135150-79-6
EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.
Formula:
C23H15ClFN3OS2
Purity:
97.55%
Color and Shape:
Liquid
Molecular weight:
467.97
Ref: TM-T79861
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € | ||
| 500mg | 3,734.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
EGFR/CSC-IN-1
CAS:2820447-02-5
EGFR/CSC-IN-1 is a dual inhibitor targeting both the epidermal growth factor receptor (EGFR [IC50 10.52 …
Formula:
C54H54Cl2FN7O7S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1067.08
Ref: TM-T73995
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 29 May 2025
Labuxtinib
CAS:1426449-01-5
Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].
Formula:
C20H16FN5O2
Purity:
99.77%
Color and Shape:
Liquid
Molecular weight:
377.37
Ref: TM-T79851
| 1mg | 139.00 € | ||
| 5mg | 338.00 € | ||
| 10mg | 540.00 € | ||
| 25mg | 1,074.00 € | ||
| 50mg | 1,549.00 € | ||
| 100mg | 2,080.00 € | ||
| 200mg | 2,802.00 € | ||
| 1mL*10mM (DMSO) | 374.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
YS-363
CAS:2470908-90-6
YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor …
Formula:
C30H30N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
494.58
Ref: TM-T80748
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 29 May 2025
EGFR-IN-1 hydrochloride
CAS:2227455-78-7
EGFR-IN-1 HCl targets L858R/T790M EGFR mutants over wild-type; IC50: 4 nM in H1975, 28 nM …
Formula:
C28H31ClN6O4
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
551.04
Ref: TM-T11157L
| 1mg | 65.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 620.00 € | ||
| 200mg | 838.00 € | ||
| 1mL*10mM (DMSO) | 202.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
Simotinib
CAS:944258-89-3
Simotinib (AL-6802) is an EGFR tyrosine kinase inhibitor (IC50 : 19.9 nM) with antitumour activity …
Formula:
C25H26ClFN4O4
Purity:
99.7%
Color and Shape:
Liquid
Molecular weight:
500.95
Ref: TM-T35916
| 1mg | 190.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
BGB-8035
CAS:2283349-24-4
BGB-8035 is a BTK inhibitor with antitumor activity that inhibits BTK, TEC, and EGFR.BGB-8035 is …
Formula:
C24H31N5O4
Purity:
96.74%
Color and Shape:
Liquid
Molecular weight:
453.53
Ref: TM-T73381
| 1mg | 393.00 € | ||
| 5mg | 933.00 € | ||
| 10mg | 1,254.00 € | ||
| 25mg | 1,872.00 € | ||
| 50mg | 2,452.00 € | ||
| 100mg | 3,230.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
Lifirafenib
CAS:1446090-79-4
Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays …
Formula:
C25H17F3N4O3
Purity:
98% - 98.25%
Color and Shape:
Solid
Molecular weight:
478.42
Ref: TM-T22272
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Thursday 29 May 2025
