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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • Cloperastine fendizoate

    CAS:
    <p>Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).</p>
    Formula:C40H38ClNO5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:648.19
  • Falnidamol

    CAS:
    <p>Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.</p>
    Formula:C18H19ClFN7
    Purity:98.816%
    Color and Shape:Solid
    Molecular weight:387.84
  • A-935142

    CAS:
    <p>A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.</p>
    Formula:C18H19F3N2O2
    Purity:98.97% - 99.91%
    Color and Shape:Solid
    Molecular weight:352.35
  • EMI1

    CAS:
    <p>EMI1 targets mutated EGFR in drug-resistant NSCLC research.</p>
    Formula:C20H18N2O3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:334.37
  • EGFR-IN-9

    CAS:
    <p>EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M).</p>
    Formula:C29H24N4O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:476.53
  • Rezivertinib

    CAS:
    <p>Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.</p>
    Formula:C27H30N6O3
    Purity:99.26% - 99.89%
    Color and Shape:Solid
    Molecular weight:486.57
  • Epitinib succinate

    CAS:
    <p>Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.</p>
    Formula:C28H32N6O6
    Purity:98.02% - 99.79%
    Color and Shape:Solid
    Molecular weight:548.59
  • Sunvozertinib

    CAS:
    <p>Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.</p>
    Formula:C29H35ClFN7O3
    Purity:98.11% - 99.63%
    Color and Shape:Solid
    Molecular weight:584.08
  • Tyrphostin A25

    CAS:
    <p>Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.</p>
    Formula:C10H6N2O3
    Purity:98.76%
    Color and Shape:Yellow Green Powder /Off-White Solid
    Molecular weight:202.17
  • PD 174265

    CAS:
    <p>PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.</p>
    Formula:C17H15BrN4O
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:371.23
  • EGFR-IN-99

    CAS:
    <p>EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).</p>
    Formula:C25H22FN7O3
    Purity:97.75%
    Color and Shape:Solid
    Molecular weight:487.49
  • Larotinib

    CAS:
    <p>Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.</p>
    Formula:C24H26ClFN4O4
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:488.94
  • SKLB 1028

    CAS:
    <p>SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.</p>
    Formula:C24H29N9
    Purity:99.90% - >99.99%
    Color and Shape:Solid
    Molecular weight:443.55
  • PKI-166

    CAS:
    <p>PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth &amp; spread of many human cancers, including pancreatic.</p>
    Formula:C20H18N4O
    Purity:99.2%
    Color and Shape:Solid
    Molecular weight:330.38
  • CGP77675

    CAS:
    <p>CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and</p>
    Formula:C26H29N5O2
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:443.54
  • LY 456236 hydrochloride

    CAS:
    <p>LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.</p>
    Formula:C16H16ClN3O2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:317.77
  • HKI-357

    CAS:
    <p>HKI-357 irreversibly inhibits EGFR/ERBB2 (IC50: 34/33 nM), blocks EGFR Y1068 autophosphorylation, and AKT/MAPK phosphorylation.</p>
    Formula:C31H29ClFN5O3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:574.05
  • EGFR-IN-29

    CAS:
    <p>EGFR-IN-29 is a potent EGFR inhibitor.</p>
    Formula:C36H46BrN8O2P
    Color and Shape:Solid
    Molecular weight:733.68
  • EGFR-IN-30

    CAS:
    <p>EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, &lt;1 nM WT/mutants) with potential in cancer research.</p>
    Formula:C28H33BrN7O2P
    Color and Shape:Solid
    Molecular weight:610.49
  • Labuxtinib

    CAS:
    <p>Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].</p>
    Formula:C20H16FN5O2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:377.37