Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 125 products of "Caspase"
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Aspirin
CAS:<p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:White Solid CrystallineMolecular weight:180.16Thiabendazole
CAS:<p>Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.</p>Formula:C10H7N3SPurity:99.14%Color and Shape:Light Yellow PowderMolecular weight:201.25Diclofenac diethylamine
CAS:<p>Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).</p>Formula:C18H22Cl2N2O2Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:369.29Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formula:C27H44O7Purity:99.06% - 99.67%Color and Shape:Canary Yellow Fine PowderMolecular weight:480.63Diclofenac
CAS:<p>Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.</p>Formula:C14H11Cl2NO2Purity:99.69% - 99.97%Color and Shape:Crystals From Ether-Petroleum Ether SolidMolecular weight:296.15Lacidipine
CAS:<p>Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.</p>Formula:C26H33NO6Purity:99.98%Color and Shape:White-To-Off-White Crystalline SolidMolecular weight:455.54Ac-FLTD-CMK
CAS:<p>Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.</p>Formula:C26H37ClN4O8Purity:95.17%Color and Shape:SolidMolecular weight:569.05Ac-YVAD-CMK
CAS:<p>Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.</p>Formula:C24H33ClN4O8Purity:97.08% - 99.909%Color and Shape:SolidMolecular weight:540.99Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purity:98.22% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09Q-VD-OPH
CAS:<p>Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12.</p>Formula:C26H25F2N3O6Purity:97.8% - 98.95%Color and Shape:SolidMolecular weight:513.5Diclofenac sodium
CAS:<p>Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.</p>Formula:C14H10Cl2NNaO2Purity:98.21% - 99.73%Color and Shape:White Or Off-White PowderMolecular weight:318.13Fenbufen
CAS:<p>Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.</p>Formula:C16H14O3Purity:98.35% - 98.46%Color and Shape:White SolidMolecular weight:254.28Dehydrocorydaline chloride
CAS:<p>Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.</p>Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88ML-9
CAS:<p>ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.</p>Formula:C15H18Cl2N2O2SPurity:99.69%Color and Shape:Crystalline SolidMolecular weight:361.29Terfenadine
CAS:<p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>Formula:C32H41NO2Purity:98.76% - 99.75%Color and Shape:SolidMolecular weight:471.67Oxidopamine hydrochloride
CAS:<p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>Formula:C8H12ClNO3Purity:98.34% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64Ac-Trp-Glu-His-Asp-Aldehyde
CAS:<p>Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].</p>Formula:C28H33N7O9Color and Shape:SolidMolecular weight:611.6TNF-α-IN-11
<p>TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM.</p>Formula:C24H26N2O5Color and Shape:SolidMolecular weight:422.47IRF1-IN-2
CAS:<p>IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.</p>Formula:C18H20N2O4SPurity:99.85%Color and Shape:SolidMolecular weight:360.43TD1092
<p>TD1092, a pan-IAP degrader, activates caspase 3/7, induces apoptosis in cancer cells, inhibits NF-κB, and is used in cancer research.</p>Formula:C55H70N8O9Color and Shape:SolidMolecular weight:987.19
