IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Found 66 products of "IAP"
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MV1
CAS:<p>MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.</p>Formula:C33H44N4O5Purity:99.86%Color and Shape:SolidMolecular weight:576.73SM-164 Hydrochloride (957135-43-2 free base)
<p>SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.</p>Formula:C62H85ClN14O6Purity:98%Color and Shape:SolidMolecular weight:1157.88S2/IAPinh
<p>S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).</p>Formula:C52H75Cl2FN6O6SMolecular weight:1000.48299N-Deshydroxyethyl Dasatinib
CAS:<p>N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP</p>Formula:C20H22ClN7OSPurity:95.96%Color and Shape:SolidMolecular weight:443.95XIAP BIR2/BIR2-3 inhibitor-3
CAS:<p>XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].</p>Formula:C86H106N18O16S2Color and Shape:SolidMolecular weight:1712XIAP BIR2/BIR2-3 inhibitor-1
CAS:<p>XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].</p>Formula:C72H96N16O14Color and Shape:SolidMolecular weight:1409.63SBP-0636457
CAS:<p>SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.</p>Formula:C25H36N4O4Color and Shape:SolidMolecular weight:456.587CST626
CAS:<p>CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.</p>Formula:C61H82N8O9SPurity:95.87%Color and Shape:SolidMolecular weight:1103.42Anti-CD47 Antibody (8A121)
<p>Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody-PE (9X161)
<p>Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (8K78)
<p>Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (4E249)
<p>Anti-CD47 Antibody (4E249) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (4E249) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (5R542)
<p>Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (5K435)
<p>Anti-CD47 Antibody (5K435) is an antibody targeting CD47. Anti-CD47 Antibody (5K435) can be used in ELISA, WB, IHC, IF.</p>Color and Shape:Odour LiquidCD47 Protein, Mouse, Recombinant (rFc)
<p>CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:39.9 kDa (predicted)Anti-CD47 Antibody (5S892)
<p>Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (9X161)
<p>Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody-FITC (9X161)
<p>Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (4C168)
<p>Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (6T428)
<p>Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (5E321)
<p>Anti-CD47 Antibody (5E321) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (5E321) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-CD47 Antibody (1F304)
<p>Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FCM.</p>Color and Shape:Odour LiquidAZD5582
CAS:<p>AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.</p>Formula:C58H78N8O8Purity:98.75%Color and Shape:SolidMolecular weight:1015.29CD47 Protein, Mouse, Recombinant (His)
<p>CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Purity:SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Color and Shape:Lyophilized PowderMolecular weight:15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
<p>Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is</p>Purity:92.7%Color and Shape:Lyophilized PowderMolecular weight:54.1 kDa (predicted); 66 kDa (reducing conditions)CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
<p>CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.</p>Color and Shape:Lyophilized PowderMolecular weight:30-40 KDa (reducing condition)CD47 Protein, Human, Recombinant (hFc)
<p>CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCColor and Shape:Lyophilized PowderMolecular weight:40.5 kDa (predicted); 55-65 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (mFc)
<p>CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:48-65 KDa (reducing condition)CD47 Protein, Rhesus macaque, Recombinant (hFc)
<p>CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:60-90 KDa (reducing condition)CD47 Protein, Human, Recombinant (aa 19-139, His)
<p>CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag.</p>Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted); 40-55 kDa (reducing conditions)Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
<p>Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal</p>Color and Shape:Lyophilized PowderMolecular weight:54.5 kDa (predicted). Due to glycosylation, the protein migrates to 63-73 kDa based on Tris-Bis PAGE result.CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
<p>CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:60-70 KDa (reducing condition)Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
<p>Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal</p>Color and Shape:Lyophilized PowderMolecular weight:53.10 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
<p>CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.</p>Color and Shape:Lyophilized PowderMolecular weight:33-55 KDa (reducing condition)CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
<p>CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:17.1 kDa (predicted); 38.8 kDa (reducing conditions)Alkaline phosphatase Protein, Human, Recombinant (hFc)
<p>Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:79.5 kDa (predicted); 90-95 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (aa 1-139, His)
<p>CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag.</p>Purity:SDS-PAGE: 98.4%; SEC-HPLC: 97.6%Color and Shape:Lyophilized PowderMolecular weight:15.2 kDa (predicted); 35-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (His)
<p>CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Purity:Greater than 95% as determined by reducing SDS-PAGE. - SDS-PAGE: 100%; SEC-HPLC: 97%Color and Shape:Lyophilized PowderMolecular weight:30-45 KDa (reducing condition)CD47 Protein, Human, Recombinant, Biotinylated
<p>CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells.</p>Purity:97.6%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted)CD47 Protein, Mouse, Recombinant
<p>CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.</p>Color and Shape:Lyophilized PowderMolecular weight:13.8 kDa (predicted)CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
<p>CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.</p>Color and Shape:Lyophilized PowderMolecular weight:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
<p>CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
<p>CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.</p>Purity:97.8%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase Protein, Human, Recombinant (His)
<p>Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Purity:98.4%Color and Shape:Lyophilized PowderMolecular weight:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39GDC-0152
CAS:<p>GDC-0152 is a potent inhibitor of IAPs.</p>Formula:C25H34N6O3SPurity:97.18% - 99.32%Color and Shape:SolidMolecular weight:498.64Birinapant
CAS:<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formula:C42H56F2N8O6Purity:97.08% - ≥95%Color and Shape:SolidMolecular weight:806.94ASTX660
CAS:<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:SolidMolecular weight:539.68Xevinapant
CAS:<p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>Formula:C32H43N5O4Purity:98% - 99.94%Color and Shape:SolidMolecular weight:561.71LCL161
CAS:<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H33FN4O3SPurity:99.13% - 99.87%Color and Shape:SolidMolecular weight:500.63Isolinderalactone
CAS:<p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>Formula:C15H16O3Purity:99.62%Color and Shape:SolidMolecular weight:244.29Polygalacin D
CAS:<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Formula:C57H92O27Purity:98.95% - ≥98%Color and Shape:SolidMolecular weight:1209.44-Methylsalicylic acid
CAS:<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Formula:C8H8O3Purity:99.64%Color and Shape:Solid Solid CrystallineMolecular weight:152.15SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Formula:C62H84N14O6Purity:98.53% - 99.92%Color and Shape:SolidMolecular weight:1121.42MX69
CAS:<p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>Formula:C27H26N2O4SPurity:97.27% - 99.57%Color and Shape:SolidMolecular weight:474.57BV6
CAS:<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Formula:C70H96N10O8Purity:97.46% - 99.82%Color and Shape:SolidMolecular weight:1205.57AZD5582 acetate (1258392-53-8 free base)
<p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>Formula:C60H82N8O10Purity:97.76%Color and Shape:SolidMolecular weight:1075.36T-3256336
CAS:<p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>Formula:C31H45F2N5O5Purity:98%Color and Shape:SolidMolecular weight:605.72MX107
CAS:<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formula:C24H28N2O2Color and Shape:SolidMolecular weight:376.49A 410099.1
CAS:<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Formula:C27H41ClN4O3Purity:99.30%Color and Shape:SolidMolecular weight:505.1MDM2/XIAP-IN-3
CAS:<p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>Formula:C29H30N2O5SColor and Shape:SolidMolecular weight:518.62CUDC-427
CAS:<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Formula:C29H36N6O4SPurity:99.92%Color and Shape:SolidMolecular weight:564.7Anticancer agent 128
CAS:<p>Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19</p>Formula:C26H38N4O4Purity:98%Color and Shape:SolidMolecular weight:470.6Anticancer agent 127
CAS:<p>Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,</p>Formula:C26H37FN4O6SPurity:98%Color and Shape:SolidMolecular weight:552.66XIAP degrader-1
<p>XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).</p>Formula:C34H45N5O4Color and Shape:SolidMolecular weight:587.75XIAP/cIAP1 antagonist-1
<p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>Color and Shape:Solid
