Survivin
Survivin inhibitors target the survivin protein, a member of the inhibitor of apoptosis (IAP) family that is highly expressed in cancer cells and helps them evade apoptosis. Survivin plays a key role in cell cycle regulation and inhibition of apoptosis, making it a critical target in cancer therapy. By inhibiting survivin, these compounds can promote apoptosis in cancer cells, offering potential therapeutic benefits. At CymitQuimica, we offer a selection of high-quality survivin inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Found 14 products of "Survivin"
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MNK8
CAS:MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Formula:C15H12N2O2Purity:99.74%Color and Shape:SolidMolecular weight:252.27ZLDI-8
CAS:ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
Formula:C24H23N3O3SPurity:98.09%Color and Shape:SolidMolecular weight:433.52MX106-4C
MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.Formula:C23H25BrN2O2Molecular weight:440.10994HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Color and Shape:Lyophilized PowderMolecular weight:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.NSC 80467
CAS:NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Formula:C24H22BrN3O5Purity:99.25%Color and Shape:SolidMolecular weight:512.35HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Color and Shape:Lyophilized PowderMolecular weight:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Color and Shape:Lyophilized PowderMolecular weight:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.LQZ-7I
CAS:LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumorsFormula:C20H14F2N4Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:348.35Cucurbitacin IIA
CAS:1.Formula:C32H50O8Purity:98.62% - 99.87%Color and Shape:SolidMolecular weight:562.73Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purity:98.76%Color and Shape:SolidMolecular weight:244.291-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.Formula:C21H13ClF3N3O2Purity:99.41%Color and Shape:SolidMolecular weight:431.8Ref: TM-T22424
1mg42.00€2mg55.00€5mg88.00€10mg127.00€25mg264.00€50mg432.00€100mg622.00€200mg873.00€1mL*10mM (DMSO)99.00€Sepantronium bromide
CAS:Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Formula:C20H19BrN4O3Purity:99.68% - 99.85%Color and Shape:SolidMolecular weight:443.26GDP366
CAS:GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.Formula:C20H17N5OSPurity:98.78% - 99.84%Color and Shape:SolidMolecular weight:375.45AQIM-I
CAS:AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].
Formula:C17H13IN2O2Color and Shape:SolidMolecular weight:404.20
