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Survivin

Survivin

Survivin inhibitors target the survivin protein, a member of the inhibitor of apoptosis (IAP) family that is highly expressed in cancer cells and helps them evade apoptosis. Survivin plays a key role in cell cycle regulation and inhibition of apoptosis, making it a critical target in cancer therapy. By inhibiting survivin, these compounds can promote apoptosis in cancer cells, offering potential therapeutic benefits. At CymitQuimica, we offer a selection of high-quality survivin inhibitors to support your research in oncology, apoptosis, and therapeutic development.

Found 14 products of "Survivin"

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  • MNK8 
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    MNK8 

    CAS:
    MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.
    Formula:C15H12N2O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:252.27

    Ref: TM-T9945

  • ZLDI-8
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    ZLDI-8

    CAS:
    <p>ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.</p>
    Formula:C24H23N3O3S
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:433.52

    Ref: TM-T13410

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    MX106-4C

    MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.
    Formula:C23H25BrN2O2
    Molecular weight:440.10994

    Ref: TM-T209442

  • HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
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    HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)

    Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.
    Color and Shape:Lyophilized Powder
    Molecular weight:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.

    Ref: TM-TMPK-01517

  • NSC 80467
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    NSC 80467

    CAS:
    NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.
    Formula:C24H22BrN3O5
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:512.35

    Ref: TM-T38414

  • HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
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    HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

    Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.
    Color and Shape:Lyophilized Powder
    Molecular weight:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.

    Ref: TM-TMPK-01480

  • HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
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    HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)

    Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.
    Color and Shape:Lyophilized Powder
    Molecular weight:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

    Ref: TM-TMPK-01516

  • LQZ-7I
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    LQZ-7I

    CAS:
    LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors
    Formula:C20H14F2N4
    Purity:99.81% - 99.87%
    Color and Shape:Solid
    Molecular weight:348.35

    Ref: TM-T8469

  • Cucurbitacin IIA
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    Cucurbitacin IIA

    CAS:
    1.
    Formula:C32H50O8
    Purity:98.62% - 99.87%
    Color and Shape:Solid
    Molecular weight:562.73

    Ref: TM-T3S1471

  • Isolinderalactone
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    Isolinderalactone

    CAS:
    Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
    Formula:C15H16O3
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:244.29

    Ref: TM-T8213

  • 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
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    1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

    CAS:
    SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.
    Formula:C21H13ClF3N3O2
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:431.8

    Ref: TM-T22424

  • Sepantronium bromide
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    Sepantronium bromide

    CAS:
    <p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>
    Formula:C20H19BrN4O3
    Purity:99.68% - 99.85%
    Color and Shape:Solid
    Molecular weight:443.26

    Ref: TM-T2111

  • GDP366
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    GDP366

    CAS:
    GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.
    Formula:C20H17N5OS
    Purity:98.78% - 99.84%
    Color and Shape:Solid
    Molecular weight:375.45

    Ref: TM-T11383

  • AQIM-I
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    AQIM-I

    CAS:
    <p>AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].</p>
    Formula:C17H13IN2O2
    Color and Shape:Solid
    Molecular weight:404.20

    Ref: TM-T85715