Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Found 226 products of "Ferroptosis"
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FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66Ref: TM-T4066
2mg42.00€5mg63.00€10mg89.00€25mg192.00€50mg341.00€100mg535.00€200mg748.00€1mL*10mM (DMSO)72.00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:374.34Ref: TM-TJS1159
1mg57.00€5mg120.00€10mg178.00€25mg329.00€50mg485.00€100mg692.00€500mg1,404.00€1mL*10mM (DMSO)215.00€Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:367.3Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Formula:C16H17BrN2SPurity:99.24% - 99.74%Color and Shape:SolidMolecular weight:349.29Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Color and Shape:SolidMolecular weight:377.31L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Formula:C8H19ClN2O3SColor and Shape:SolidMolecular weight:258.77Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formula:C18H28N2O·HClPurity:99.74%Color and Shape:White Crystalline PowderMolecular weight:324.89Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Formula:C12H22FeN3O14Purity:98%Color and Shape:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaMolecular weight:488.16Pioglitazone potassium
CAS:Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.Formula:C19H19KN2O3SColor and Shape:SolidMolecular weight:394.53CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purity:98.3% - 99.61%Color and Shape:SolidMolecular weight:541.72Ref: TM-TQ0120
1mg34.00€5mg74.00€10mg105.00€25mg200.00€50mg319.00€100mg485.00€500mg1,035.00€1mL*10mM (DMSO)89.00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.64(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFormula:C15H14O6Purity:98.55% - 98.80%Color and Shape:SolidMolecular weight:290.27CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Formula:C23H27N3O5S2Purity:99.46% - 99.91%Color and Shape:SolidMolecular weight:489.61Ref: TM-T4309
1mg34.00€2mg49.00€5mg74.00€10mg109.00€25mg178.00€50mg284.00€100mg434.00€1mL*10mM (DMSO)81.00€Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purity:97.169% - 99.59%Color and Shape:Dark Purple Crystalline PowderMolecular weight:651.94DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFormula:C15H24O2Purity:99.06% - 99.17%Color and Shape:SolidMolecular weight:236.35Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Formula:C15H20O3Purity:98% - 99.8%Color and Shape:SolidMolecular weight:248.32UAMC-3203
CAS:UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).Formula:C25H37N5O2SPurity:97.052% - 99.72%Color and Shape:SolidMolecular weight:471.66Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25Ref: TM-T4414
5mg70.00€10mg100.00€25mg195.00€50mg349.00€100mg618.00€500mg1,251.00€1mL*10mM (DMSO)77.00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purity:99.99%Color and Shape:White Or Off-White PowderMolecular weight:146.14RSL3
CAS:View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.Formula:C23H21ClN2O5Purity:98% - 99.96%Color and Shape:SolidMolecular weight:440.88Ref: TM-T3646
1g1,288.00€1mg37.00€2mg49.00€5mg74.00€10mg119.00€25mg244.00€50mg331.00€100mg434.00€500mg973.00€1mL*10mM (DMSO)71.00€Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purity:97.03% - 99.90%Color and Shape:SolidMolecular weight:317.34DL-α-Tocopherol
CAS:DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.Formula:C29H50O2Purity:99.61% - 99.90%Color and Shape:Light Yellow Liquid ViscousMolecular weight:430.71(E)-Ferulic acid
CAS:(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression ofFormula:C10H10O4Purity:99.63%Color and Shape:SolidMolecular weight:194.18SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Ref: TM-T8922
1mg46.00€5mg80.00€10mg116.00€25mg227.00€50mg359.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)105.00€Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formula:C11H11NO4SPurity:98.71%Color and Shape:SolidMolecular weight:253.27Ref: TM-T19692
1mg99.00€5mg222.00€10mg344.00€25mg550.00€50mg773.00€100mg1,063.00€1mL*10mM (DMSO)205.00€ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurity:98.42% - 99.55%Color and Shape:SolidMolecular weight:477.4Ref: TM-T8970
1mg43.00€5mg85.00€10mg110.00€25mg215.00€50mg334.00€100mg467.00€200mg672.00€1mL*10mM (DMSO)92.00€1R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Formula:C23H21ClN2O5Purity:99.51%Color and Shape:SolidMolecular weight:440.88Ref: TM-T9561
1mg86.00€5mg177.00€10mg265.00€25mg427.00€50mg605.00€100mg800.00€200mg1,071.00€1mL*10mM (DMSO)207.00€Piperazine Erastin
CAS:Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.Formula:C35H41ClN6O4Purity:99.52%Color and Shape:SolidMolecular weight:645.19Ref: TM-T16540
1mg92.00€5mg165.00€10mg268.00€25mg537.00€50mg879.00€100mg1,161.00€200mg1,594.00€500mg2,367.00€1mL*10mM (DMSO)227.00€PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.
Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Formula:C21H19ClN4O2Purity:93.468% - 99.31%Color and Shape:SolidMolecular weight:394.85Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Formula:C14H15N5SPurity:99% - 99.02%Color and Shape:SolidMolecular weight:285.37Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formula:C15H28O3Purity:97.27%Color and Shape:SoildMolecular weight:256.38Frataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Formula:C20H23NO6Purity:99.34%Color and Shape:SolidMolecular weight:373.4Microtubule inhibitor 8
CAS:Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].Formula:C21H15N3O2SColor and Shape:SolidMolecular weight:373.43Pioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Formula:C19H20N2O3SPurity:98%Color and Shape:SolidMolecular weight:360.46IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Color and Shape:SolidMolecular weight:368.47CN128 hydrochloride
CAS:CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.
Formula:C15H18ClNO3Color and Shape:SolidMolecular weight:295.76Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formula:C22H19N3O5Color and Shape:SolidMolecular weight:405.4Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purity:98%Color and Shape:SolidMolecular weight:578.58YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.Formula:C25H26N6OColor and Shape:SolidMolecular weight:426.51W1131
CAS:W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Formula:C23H19N5O4Color and Shape:SolidMolecular weight:429.43CGP 65015
CAS:CGP 65015 is an oral iron chelator and can mobilize iron deposits.Formula:C14H15NO4Purity:98%Color and Shape:SolidMolecular weight:261.27Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Formula:C17H24ClN3O2Molecular weight:337.84Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Color and Shape:SolidMolecular weight:464.9NPD4928
CAS:NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formula:C29H32N2O6Color and Shape:SolidMolecular weight:504.57FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurity:99.44%Color and Shape:SolidMolecular weight:468.54BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Formula:C20H24N2O6Purity:97.35% - 98.58%Color and Shape:SolidMolecular weight:388.41Deferitazole
CAS:Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Formula:C18H25NO7SPurity:99.48%Color and Shape:SolidMolecular weight:399.46
