CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 500 products of "CDK"
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PROTAC CDK9 degrader-6
CAS:<p>PROTAC CDK9 degrader-6 targets and degrades CDK9 isoforms via proteasome, with DC50 of 0.10μM and 0.14μM.</p>Formula:C42H49Cl2N9O8Purity:98%Color and Shape:SolidMolecular weight:878.8CDK12/13-IN-2
<p>CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12 and CDK13, exhibiting IC50 values of 15.5 nM and 12.2 nM, respectively. It effectively inhibits the proliferation of breast cancer cells and can be utilized in the research of triple-negative breast cancer.</p>Formula:C24H22FN7O2Color and Shape:SolidMolecular weight:459.48PF07104091
CAS:<p>PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation. Cost-effective and quality-assured.</p>Formula:C19H28N6O4Purity:99.49%Color and Shape:SolidMolecular weight:404.46TMX-2039
CAS:<p>TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.</p>Formula:C17H20BrFN6O3SColor and Shape:SolidMolecular weight:487.347NecroIr1
<p>NecroIr1, an iridium(III) complex, induces necroptosis in Cisplatin-resistant lung cells, targeting mitochondria and disrupting MMP.</p>Formula:C40H29ClIrN5OColor and Shape:SolidMolecular weight:823.36CDK8-IN-12
CAS:<p>CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.</p>Formula:C21H20ClN3O2Purity:99.46% - 99.83%Color and Shape:SoildMolecular weight:381.86A-130A
CAS:<p>A-130A is a polycyclic polyether compound belonging to the nigericin group of antibiotics generated by Streptomyces hygroscopicus strain.</p>Formula:C47H78O13Purity:98%Color and Shape:SolidMolecular weight:851.11CDK7-IN-7
CAS:<p>CDK7-IN-7: Selective CDK7 inhibitor, IC50 < 50 nM (Patent CN112661745A).</p>Formula:C20H20BrF3N6O2Color and Shape:SolidMolecular weight:513.319Roccellic Acid
CAS:<p>Roccellic acid from R. montagnei lichen has antibacterial, anticancer properties; MIC 46.9 μg/ml; inhibits cancer cells by up to 87.9%.</p>Formula:C17H32O4Color and Shape:SolidMolecular weight:300.43CDK12-IN-4
CAS:<p>CDK12-IN-4 is a pyrazolotriazine that inhibits CDK12 (IC50: 0.641 μM) with high ATP (2 mM) and spares CDK2/Cyclin E and CDK9/Cyclin T1 (IC50: >20 μM).</p>Formula:C20H20F2N8OColor and Shape:SolidMolecular weight:426.432IV-361
CAS:<p>IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1</p>Formula:C23H32FN5O2SiColor and Shape:SolidMolecular weight:457.625EGFR/CDK2-IN-2
<p>EGFR/CDK2-IN-2 (compound 6a) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 values of 19.6 nM and 87.9 nM, respectively.</p>Formula:C49H32N12O2S2Purity:98%Color and Shape:SolidMolecular weight:884.99Multi-target kinase inhibitor 2
<p>Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values</p>Purity:98%Color and Shape:Odour SolidCDK-TCIP2
<p>DK-TCIP2 is an anticancer agent formed by linking the CDK9 inhibitor SNS-032 and the BCL6 inhibitor BI-3812. This compound exhibits anticancer activity both in vivo and in vitro, making it suitable for research in lymphoma.</p>Formula:C52H67ClN12O8S2Color and Shape:SolidMolecular weight:1087.75CDK2/4-IN-1
<p>CDK2/4-IN-1 (compound B-4a) serves as both a CDK2/4 inhibitor and a microtubule polymerization inhibitor, making it useful in cancer research.</p>Color and Shape:Odour SolidEGFR/CDK2-IN-4
<p>EGFR/CDK2-IN-4 (compound 4c) is a dual inhibitor targeting EGFR and CDK-2, demonstrating IC50 values of 89.6 nM for EGFR and 165.4 nM for CDK-2.</p>Formula:C24H16N6OS2Purity:98%Color and Shape:SolidMolecular weight:468.55CDK6/9-IN-1
CAS:<p>CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).</p>Formula:C22H25ClN8OColor and Shape:SolidMolecular weight:452.95CDK9-IN-26
<p>CDK9-IN-26, also known as compound 1, is a potent inhibitor of Cyclin-Dependent Kinase 9 (CDK9) with an IC50 value of 0.18 μM.[1]</p>Formula:C17H14N4O2Purity:98%Color and Shape:SolidMolecular weight:306.32BSJ-04-132
<p>Selective Cdk4 degrader. Degrades Cdk4 in Molt-4 cells, with no effect on Cdk6 levels. Displays cereblon-dependent degradation.</p>Color and Shape:Liquid(1S,3R,5R)-PIM447 dihydrochloride
<p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>Formula:C24H25Cl2F3N4OPurity:98%Color and Shape:SolidMolecular weight:513.38WAY-322243
CAS:<p>WAY-322243 has antibacterial and anti-inflammatory activity and has an inhibitory effect on CLK-1, which can be used to study Alzheimer's disease.</p>Formula:C18H18N2O2SPurity:99.88%Color and Shape:SoildMolecular weight:326.41PROTAC CDK9 degrader-5
CAS:<p>PROTAC CDK9 degrader-5 selectively degrades CDK9 isoforms 42, 55 with DC50 of 0.10μM, 0.14μM via proteasome.</p>Formula:C42H48Cl2N8O9Purity:98%Color and Shape:SolidMolecular weight:879.78CDK12-IN-2
CAS:<p>CDK12-IN-2 selectively inhibits CDK12 (IC50: 52 nM) with minimal effect on CDK2, CDK7, and CDK9, useful for CDK12 research.</p>Formula:C32H32N6O2Purity:99.31%Color and Shape:SolidMolecular weight:532.64PROTAC CDK9 degrader 4
CAS:<p>PROTAC CDK9 degrader 4 is a CDK9 degrader that targets transcriptional regulation and has potential anticancer activity.</p>Formula:C43H56N10O5Color and Shape:SolidMolecular weight:792.973MB-PP1
CAS:<p>3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor.</p>Formula:C17H21N5Purity:99.96%Color and Shape:White SolidMolecular weight:295.38CDK7-IN-2 hydrochloride hydrate
CAS:<p>CDK7-IN-2 HCl hydrate is a potent, specific CDK7 enzyme inhibitor with significant anti-cancer effects.</p>Formula:C26H42ClN7O4Color and Shape:SolidMolecular weight:552.12CDK7/9-IN-1
CAS:<p>CDK7/9-IN-1 inhibits CDK7/9 with IC50: 0.0656 μM (no pre-incubation), 0.00574 μM (3h pre-inc.), and CDK9: 2.14 μM (3h pre-inc.) for cancer research.</p>Formula:C24H32F3N5O2Color and Shape:SolidMolecular weight:479.548Flavopiridol
CAS:<p>Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; also inhibits EGFR, PKA. In Phase 1/2 trials.</p>Formula:C21H20ClNO5Purity:97.74% - 99.86%Color and Shape:SolidMolecular weight:401.84WAY-647802
CAS:<p>WAY-647802 is a CDK inhibitor.</p>Formula:C11H14N4O3Purity:99.53%Color and Shape:SolidMolecular weight:250.25CDK-IN-12
CAS:<p>CDK-IN-12 (Example 20), a CDK inhibitor, effectively inhibits CDK4/6, demonstrating IC50 values below 20 nM [1].</p>Formula:C26H29FN6OSColor and Shape:SolidMolecular weight:492.61CGP-74514
CAS:<p>CGP-74514,CDK1 inhibitor (IC50=25 nM). Induces G2/M arrest, apoptosis. Used in bladder cancer research.</p>Formula:C19H24ClN7Purity:98.54%Color and Shape:SoildMolecular weight:385.89CDK1-IN-2
CAS:<p>CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.</p>Formula:C17H11ClN2OPurity:98.53%Color and Shape:SoildMolecular weight:294.73CDK5-IN-3
CAS:<p>CDK5-IN-3 is a selective and potent CDK5 inhibitor that inhibits CDK5/p25 and CDK2/CycA, and can be used in the study of cancer.</p>Formula:C22H26N4OPurity:98.21%Color and Shape:SolidMolecular weight:362.47Palbociclib-d8
CAS:<p>Palbociclib-d8 (PD 0332991 D8) is the deuterated form of Palbociclib. Palbociclib is a CDK inhibitor that inhibits CDK4 and CDK6.</p>Formula:C24H21D8N7O2Purity:98%Color and Shape:SolidMolecular weight:455.58NCT02
CAS:<p>NCT02 degrades cyclin K, leading to CCNK and CDK12 degradation, potentially aiding metastatic CRC research.</p>Formula:C17H16N2O2SColor and Shape:SolidMolecular weight:312.39TG003
CAS:<p>TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.</p>Formula:C13H15NO2SPurity:99.46%Color and Shape:SolidMolecular weight:249.33GP-82996
CAS:<p>GP-82996 (CINK4) inhibits CDK4/6; IC50s: 1.5 μM (CDK4/D1), 5.6 μM (CDK6/D1), 25 μM (Cdk5/p35); triggers U2OS cancer cell apoptosis.</p>Formula:C27H32N6OPurity:99.94%Color and Shape:SolidMolecular weight:456.58(E/Z)-Zotiraciclib hydrochloride
CAS:<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.</p>Formula:C23H25ClN4OColor and Shape:SolidMolecular weight:408.93LDC4297
CAS:<p>LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.</p>Formula:C23H28N8OPurity:98.25%Color and Shape:SolidMolecular weight:432.52NU6102
CAS:<p>NU6102 is a CDK2 inhibitor with antitumor activity against CDK1/cyclinB, CDK1/CDK2, CDK4, DYRK1A , PDK1, and ROCKII, and it can be used to study rectal cancer.</p>Formula:C18H22N6O3SPurity:99.76%Color and Shape:SolidMolecular weight:402.47Palbociclib hydrochloride
CAS:<p>Palbociclib hydrochloride is the salt form of Palbociclib, a selective and orally available CDK4 and CDK6 inhibitor for breast and hepatocellular carcinoma.</p>Formula:C24H31Cl2N7O2Purity:99.89%Color and Shape:SolidMolecular weight:520.46Ribociclib hydrochloride
CAS:<p>Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).</p>Formula:C23H31ClN8OPurity:98%Color and Shape:SolidMolecular weight:471FMF-04-159-2
CAS:<p>FMF-04-159-2 is a potent covalent CDK14 & CDK2 inhibito and is able to reduce α-Syn aggregation in neurons, and inhibits TNBC cancer progression.</p>Formula:C28H30Cl3N7O5SPurity:96.57%Color and Shape:SolidMolecular weight:683.01Ribociclib-d6
CAS:<p>Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.</p>Formula:C23H30N8OColor and Shape:SolidMolecular weight:440.57CDK9-IN-1
CAS:<p>CDK9-IN-1 is a selective and potent CDK9 inhibitor with antiviral activity used in the study of PRRSV infections.</p>Formula:C26H21N5O4SPurity:98.52%Color and Shape:SolidMolecular weight:499.54Dalpiciclib hydrochloride
<p>Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.</p>Formula:C25H31ClN6O2Color and Shape:SolidMolecular weight:483.01Atuveciclib
CAS:<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Formula:C18H18FN5O2SPurity:98.8%Color and Shape:SolidMolecular weight:387.43Avotaciclib trihydrochloride
CAS:<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Formula:C13H14Cl3N7OPurity:99%Color and Shape:SolidMolecular weight:390.65DRB
CAS:<p>DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)</p>Formula:C12H12Cl2N2O4Purity:99.46% - 99.83%Color and Shape:White To Off-White Crystalline SolidMolecular weight:319.14Senexin A
CAS:<p>Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.</p>Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.02LY3143921
CAS:<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Formula:C16H12FN5OColor and Shape:SolidMolecular weight:309.3Cdk5 Substrate acetate
<p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5AMG 925 HCl
CAS:<p>AMG 925 HCl is a selective and potent dual inhibitor of FLT3 (IC50: 2±1 nM) and CDK4 (IC50: 3±1 nM).</p>Formula:C26H30ClN7O2Color and Shape:SolidMolecular weight:508.02PF-06873600
CAS:<p>PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.</p>Formula:C20H27F2N5O4SPurity:98.77% - 99.55%Color and Shape:SolidMolecular weight:471.52MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46CDK9-IN-30
CAS:<p>CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.</p>Formula:C16H20FNO3Purity:99.75%Color and Shape:SolidMolecular weight:293.33AZD-5438
CAS:<p>AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).</p>Formula:C18H21N5O2SPurity:99.73% - 99.87%Color and Shape:SolidMolecular weight:371.46Flavopiridol hydrochloride
CAS:<p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>Formula:C21H21Cl2NO5Purity:98.87% - 99.88%Color and Shape:SolidMolecular weight:438.3PHA-767491 hydrochloride
CAS:<p>PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.</p>Formula:C12H12ClN3OPurity:99.56% - 99.92%Color and Shape:SolidMolecular weight:249.69Seliciclib
CAS:<p>Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.</p>Formula:C19H26N6OPurity:97.15% - 99.89%Color and Shape:White To Off-White SolidMolecular weight:354.45BSJ-03-123
CAS:<p>BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.</p>Formula:C47H56N10O11Purity:97.78% - 99.38%Color and Shape:SolidMolecular weight:937.01(E/Z)-Zotiraciclib
CAS:<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.</p>Formula:C23H24N4OPurity:97.75% - 99.92%Color and Shape:SolidMolecular weight:372.46AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formula:C16H12N2O3Purity:98.69%Color and Shape:SolidMolecular weight:280.28Indirubin-3'-monoxime
CAS:<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Formula:C16H11N3O2Purity:99.55%Color and Shape:Dark Red SolidMolecular weight:277.28JSH-150
CAS:<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Formula:C24H33ClN6O2SPurity:99.96% - 99.96%Color and Shape:SolidMolecular weight:505.08Dinaciclib
CAS:<p>Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).</p>Formula:C21H28N6O2Purity:98.21% - 99.75%Color and Shape:SolidMolecular weight:396.49THZ1 Hydrochloride
<p>THZ1 Hydrochloride: selective covalent CDK7 inhibitor, IC50 of 3.2 nM; affects CDK12/13 & lowers MYC expression.</p>Formula:C31H29Cl2N7O2Color and Shape:SolidMolecular weight:602.51PHA-767491
CAS:<p>PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.</p>Formula:C12H11N3OPurity:99.49% - >99.99%Color and Shape:SolidMolecular weight:213.24THZ1
CAS:<p>THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.</p>Formula:C31H28ClN7O2Purity:95.09% - 99.27%Color and Shape:SolidMolecular weight:566.05Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.447BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Formula:C19H23O10PSPurity:98% - 99.84%Color and Shape:SolidMolecular weight:474.42BS-181 dihydrochloride
CAS:<p>BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.</p>Formula:C22H34Cl2N6Color and Shape:SolidMolecular weight:453.462-Chloropyrazine
CAS:<p>2-Chloropyrazine is used in chemical industry.</p>Formula:C4H3ClN2Purity:98.98% - 99.89%Color and Shape:Clear Colorless To Yellowish LiquidMolecular weight:114.53(E/Z)-Zotiraciclib citrate
<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.</p>Formula:C29H32N4O8Color and Shape:SolidMolecular weight:564.59ON-013100
CAS:<p>ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.</p>Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.44FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41RGB-286638 free base
CAS:<p>RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.</p>Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63BMS-265246
CAS:<p>BMS-265246 is a potent and selective CDK1/2 inhibitor.</p>Formula:C18H17F2N3O2Purity:99.25% - 99.57%Color and Shape:SolidMolecular weight:345.34SR-4835
CAS:<p>SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (</p>Formula:C21H20Cl2N10OPurity:98.09% - >99.99%Color and Shape:SolidMolecular weight:499.36KB-0742 dihydrochloride
CAS:<p>KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.</p>Formula:C16H27Cl2N5Purity:99.79%Color and Shape:SolidMolecular weight:360.33LY3405105
CAS:<p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>Formula:C26H39N7O3Purity:99.66%Color and Shape:SolidMolecular weight:497.63HQ461
CAS:HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA repair genes, and induces cell death.Formula:C15H15N5OS2Purity:98.11%Color and Shape:SolidMolecular weight:345.44AT7519 Hydrochloride
CAS:<p>AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.</p>Formula:C16H18Cl3N5O2Purity:99.66% - 99.9%Color and Shape:SolidMolecular weight:418.71Fadraciclib
CAS:<p>Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).</p>Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52Cucurbitacin E
CAS:<p>Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.</p>Formula:C32H44O8Purity:98.88% - 99.87%Color and Shape:SolidMolecular weight:556.69MSC2530818
CAS:<p>MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).</p>Formula:C18H17ClN4OPurity:98.93%Color and Shape:SolidMolecular weight:340.81CKI-7
CAS:<p>CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Formula:C11H14Cl3N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:358.67Amantadine
CAS:<p>Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.</p>Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25Abemaciclib methanesulfonate
CAS:<p>Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).</p>Formula:C27H32F2N8·CH4O3SPurity:98.69% - 99.44%Color and Shape:SolidMolecular weight:602.7Desmethylglycitein
CAS:<p>Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has</p>Formula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24LY3177833
CAS:<p>LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)</p>Formula:C16H12FN5OPurity:99.87%Color and Shape:SolidMolecular weight:309.3SCH900776 (S-isomer)
CAS:<p>SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).</p>Formula:C15H18BrN7Purity:99.88%Color and Shape:SolidMolecular weight:376.25Dalpiciclib
CAS:<p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>Formula:C25H30N6O2Purity:99.69%Color and Shape:SolidMolecular weight:446.54BUR1
CAS:<p>BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.</p>Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34SNS-032
CAS:<p>SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.</p>Formula:C17H24N4O2S2Purity:98.27% - 99.91%Color and Shape:SolidMolecular weight:380.53CC-671
CAS:<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Formula:C28H28N6O4Purity:98.66% - 98.8%Color and Shape:SolidMolecular weight:512.56NVP-LCQ195
CAS:<p>NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).</p>Formula:C17H19Cl2N5O4SPurity:99.56% - 99.85%Color and Shape:SolidMolecular weight:460.33Aminopurvalanol A
CAS:<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Formula:C19H26ClN7OPurity:99.73%Color and Shape:SolidMolecular weight:403.91
