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CDK

CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

Found 526 products of "CDK"

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  • Olomoucine II
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    Olomoucine II

    CAS:
    Olomoucine II, a CDK inhibitor effective on Cdk1/2/4/7/9, also inhibits ERK2, ABCB1, and various virus replications, not effective on measles/influenza.
    Formula:C19H26N6O2
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:370.45

    Ref: TM-T35696

  • Cdc7-IN-1
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    Cdc7-IN-1

    CAS:
    Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.
    Formula:C21H16ClN3O4
    Color and Shape:Solid
    Molecular weight:409.82

    Ref: TM-T10724

  • SLM6
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    SLM6

    CAS:
    SLM6, an inhibitor of cyclin-dependent kinase-9 (CDK9), exhibits potent anti-multiple myeloma activity.
    Formula:C12H17N7O4
    Color and Shape:Solid
    Molecular weight:323.31

    Ref: TM-T28805

  • CLK1/2-IN-3
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    CLK1/2-IN-3

    CAS:
    CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.
    Formula:C21H21N5O2
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:375.42

    Ref: TM-T23897

  • CDK9/10/GSK3β-IN-1
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    CDK9/10/GSK3β-IN-1

    CAS:
    CDK9/10/GSK3β-IN-1 is a kinase inhibitor (Flavopiridol analogue) that effectively inhibits HsGSK3β, HsCDK9/CyclinT, HsCDK5/p25 and HsCDK2/CyclinA with IC50
    Formula:C29H24ClN3O4S
    Color and Shape:Solid
    Molecular weight:546.04

    Ref: TM-T63851

  • CDK5 inhibitor 20-223
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    CDK5 inhibitor 20-223

    CAS:
    CDK5 inhibitor 20-223 is a potent CDK2/CDK5 inhibitor,anti-Colorectal Cancer (CRC), inhibiting cell migration and inducing cell cycle arrest.
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.37

    Ref: TM-T36742

  • SMAPP1
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    SMAPP1

    CAS:
    SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells.
    Formula:C27H25N5O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:563.65

    Ref: TM-T28818

  • BAY-958
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    BAY-958

    CAS:
    BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.
    Formula:C17H16FN5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-T23775

  • CDK12-IN-E9
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    CDK12-IN-E9

    CAS:
    CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.
    Formula:C24H30N6O2
    Color and Shape:Solid
    Molecular weight:434.53

    Ref: TM-T14915

  • SLK/STK10-IN-1
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    SLK/STK10-IN-1

    CAS:
    SLK/STK10-IN-1 is a selective and potent inhibitor of SLK and STK10 with potential antitumor activity.
    Formula:C17H13ClN2O3
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:328.75

    Ref: TM-T60946

  • AS2863619 free base
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    AS2863619 free base

    CAS:
    AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.
    Formula:C16H12N8O
    Color and Shape:Solid
    Molecular weight:332.32

    Ref: TM-T10382

  • CDK7-IN-8
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    CDK7-IN-8

    CAS:
    CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.
    Formula:C25H38N8O3
    Color and Shape:Solid
    Molecular weight:498.62

    Ref: TM-T63381

  • FLT3/CDK4-IN-1
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    FLT3/CDK4-IN-1

    CAS:
    FLT3/CDK4-IN-1: Oral FLT3 (7 nM IC50) & CDK4 (11 nM IC50) inhibitor with strong in vivo anti-cancer properties.
    Formula:C25H28F2N8
    Color and Shape:Solid
    Molecular weight:478.54

    Ref: TM-T63135

  • BS-181
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    BS-181

    CAS:
    BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.
    Formula:C22H32N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.53

    Ref: TM-T1947

  • CDK7-IN-20
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    CDK7-IN-20

    CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.
    Formula:C30H26N6O3
    Color and Shape:Solid
    Molecular weight:518.57

    Ref: TM-T73163

  • SNX2-1-108
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    SNX2-1-108

    CAS:
    SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.
    Formula:C21H16N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38

    Ref: TM-T24811

  • CDK7-IN-13
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    CDK7-IN-13

    CAS:
    CDK7-IN-13 (compound 1) is an effective CDK7 inhibitor for investigating cancers associated with transcriptional dysregulation.
    Formula:C20H23F3N6OS
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:452.5

    Ref: TM-T62759

  • Indirubin-3'-monoxime-5-sulphonic acid
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    Indirubin-3'-monoxime-5-sulphonic acid

    CAS:
    Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.
    Formula:C16H11N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:357.34

    Ref: TM-T11652

  • BSJ-01-175
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    BSJ-01-175

    CAS:
    BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.
    Formula:C30H33ClN6O2
    Color and Shape:Solid
    Molecular weight:545.08

    Ref: TM-T63841

  • MDK6204
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    MDK6204

    CAS:
    MDK6204 is a selective inhibitor of CLK1 and CLK2.
    Formula:C20H20N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.41

    Ref: TM-T24439