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Microtubule Associated

Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 274 products of "Microtubule Associated"

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  • Verubulin hydrochloride

    CAS:
    Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic
    Formula:C17H18ClN3O
    Purity:98.29% - 99.77%
    Color and Shape:Solid
    Molecular weight:315.8

    Ref: TM-T13298

    5mg
    52.00€
    10mg
    73.00€
    25mg
    138.00€
    50mg
    200.00€
    100mg
    284.00€
    200mg
    411.00€
    1mL*10mM (DMSO)
    52.00€
  • Zagotenemab

    CAS:
    Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.
    Purity:> 95% - >95.0% (SDS-PAGE)
    Color and Shape:Liquid
    Molecular weight:145.3 kDa

    Ref: TM-T76726

    1mg
    152.00€
    5mg
    385.00€
    10mg
    620.00€
    25mg
    945.00€
    50mg
    1,279.00€
    100mg
    1,701.00€
  • Tubulin inhibitor 6

    CAS:
    Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.
    Formula:C20H14ClNO2S
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:367.85

    Ref: TM-T13224

    5mg
    34.00€
    10mg
    52.00€
    25mg
    86.00€
    50mg
    116.00€
    100mg
    172.00€
    500mg
    409.00€
    1mL*10mM (DMSO)
    37.00€
  • Tirbanibulin Mesylate

    CAS:
    Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
    Formula:C27H33N3O6S
    Purity:99%
    Color and Shape:Solid
    Molecular weight:527.63

    Ref: TM-T15675

    2mg
    35.00€
    5mg
    52.00€
    10mg
    66.00€
    25mg
    119.00€
    50mg
    230.00€
    100mg
    394.00€
    200mg
    532.00€
    1mL*10mM (DMSO)
    62.00€
  • Entasobulin

    CAS:
    Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
    Formula:C26H18ClN3O2
    Purity:98.40%
    Color and Shape:Solid
    Molecular weight:439.89

    Ref: TM-T15236

    5mg
    43.00€
    10mg
    60.00€
    25mg
    92.00€
    50mg
    161.00€
    100mg
    245.00€
    200mg
    353.00€
    1mL*10mM (DMSO)
    47.00€
  • Bepranemab

    CAS:
    Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.
    Purity:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:145.92 kDa

    Ref: TM-T76926

    1mg
    177.00€
    5mg
    465.00€
    10mg
    745.00€
    25mg
    1,108.00€
    50mg
    1,485.00€
  • BNC105

    CAS:
    BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
    Formula:C20H20O7
    Purity:96.57%
    Color and Shape:Solid
    Molecular weight:372.37

    Ref: TM-T14694

    1mg
    79.00€
    5mg
    152.00€
    10mg
    215.00€
    25mg
    351.00€
    50mg
    494.00€
    100mg
    665.00€
    200mg
    893.00€
    1mL*10mM (DMSO)
    167.00€
  • Tilavonemab

    CAS:
    Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.
    Purity:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:145.73kDa

    Ref: TM-T76725

    1mg
    158.00€
    5mg
    404.00€
    10mg
    643.00€
    25mg
    973.00€
    50mg
    1,314.00€
  • Tubulin Polymerization-IN-1 prodrug

    CAS:
    Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.
    Formula:C22H23FN2O4
    Color and Shape:Solid
    Molecular weight:398.43

    Ref: TM-T203394

    10mg
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    50mg
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  • Tubulin inhibitor 24

    CAS:
    Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.
    Formula:C22H21N3O3
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:375.42

    Ref: TM-T9812

    1mg
    109.00€
    5mg
    235.00€
    10mg
    349.00€
    25mg
    532.00€
    50mg
    745.00€
    100mg
    999.00€
    500mg
    2,008.00€
  • Cys-McMMAF

    CAS:
    Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.
    Formula:C52H83N7O13S
    Color and Shape:Solid
    Molecular weight:1046.32

    Ref: TM-T74880

    5mg
    To inquire
    50mg
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  • Dihydrocephalomannine

    CAS:
    Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.
    Formula:C45H55NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:833.928

    Ref: TM-T13653

    5mg
    897.00€
  • Breast cancer targeting peptide 18-4

    CAS:
    Breastcancertargeting peptide 18–4 is a keratin 1 (KRT1) receptor-targeting peptide with a dissociation constant (Kd) of 0.98 μM. Its amino acid sequence is WxEAAYQrFL, and it is an analogue of the P160 peptide. When covalently bonded with the anticancer peptide MccJ25, it significantly enhances MccJ25 uptake in breast cancer cells and boosts its anticancer efficacy. The IC50 values for this covalent compound are 14.2, 20, and 25 μM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR, respectively.
    Formula:C63H89N15O15
    Color and Shape:Solid
    Molecular weight:1296.47

    Ref: TM-TP3074

    10mg
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    50mg
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  • P160 peptide

    CAS:
    P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor in breast cancer cells, with a Kd of approximately 1.1 μM. It shows significant potential for targeted drug delivery to breast cancer cells. P160 peptide enhances the cellular uptake and anticancer activity of the pro-apoptotic antimicrobial peptide MccJ25 (microcin J25). It is applicable in cancer research studies.
    Formula:C74H105N17O17S
    Color and Shape:Solid
    Molecular weight:1536.79

    Ref: TM-TP3031

    10mg
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    50mg
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  • Anhydrovinblastine sulfate


    Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.
    Formula:C46H60N4O16S2
    Molecular weight:988.34457

    Ref: TM-TN11107

    10mg
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    50mg
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  • Pironetin

    CAS:
    Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.
    Formula:C19H32O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.45

    Ref: TM-T16543

    25mg
    2,583.00€
    50mg
    3,402.00€
    100mg
    4,680.00€
  • ER-076349

    CAS:
    ER-076349 is a microtubule polymerization inhibitor that induces G2-M cell cycle arrest and disrupts mitotic spindles. This compound inhibits the growth of cancer cells and suppresses tumor growth in various human tumor xenograft mouse models. Additionally, ER-076349 is an analog of Halichondrin B.
    Formula:C40H58O12
    Color and Shape:Solid
    Molecular weight:730.88

    Ref: TM-T200036

    25mg
    4,609.00€
    50mg
    6,103.00€
    100mg
    8,730.00€
  • cis-trismethoxy Resveratrol

    CAS:

    cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.

    Formula:C17H18O3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:270.32

    Ref: TM-T3330L

    10mg
    59.00€
    25mg
    87.00€
    50mg
    108.00€
    100mg
    156.00€
    500mg
    370.00€
  • AADvac 1 TFA


    AADvac 1 TFA is an active tau peptide vaccine utilized in Alzheimer's disease research. It is formed by conjugating the regulatory peptide 294KDNIKHVPGGGS305, which drives tau oligomerization, with keyhole limpet hemocyanin (KLH), and is formulated with aluminum hydroxide.

    Ref: TM-TP3614

    10mg
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    50mg
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  • Tubulin inhibitor 45


    Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.
    Formula:C19H18N2O2S
    Molecular weight:338.1089

    Ref: TM-T210235

    10mg
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    50mg
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  • Trimethylcolchicinic acid

    CAS:
    Trimethylcolchicinic acid is an orally available colchicine analog that binds to tubulin and inhibits its polymerization into microtubules,potential antitumor.
    Formula:C19H21NO5
    Purity:>99.99%
    Color and Shape:Soild
    Molecular weight:343.37

    Ref: TM-T204087

    1mg
    195.00€
    5mg
    422.00€
    10mg
    623.00€
    25mg
    1,058.00€
    50mg
    1,589.00€
    100mg
    2,309.00€
  • Diminutol

    CAS:
    Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.
    Formula:C19H26N6OS
    Color and Shape:Solid
    Molecular weight:386.51

    Ref: TM-T36358

    5mg
    1,234.00€
    500µg
    166.00€
  • N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide

    CAS:
    N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM
    Formula:C24H18ClN3O
    Purity:99.93%
    Color and Shape:Soild
    Molecular weight:399.87

    Ref: TM-T60041

    1mg
    109.00€
    5mg
    241.00€
    10mg
    355.00€
    25mg
    532.00€
    50mg
    745.00€
    100mg
    1,018.00€
    200mg
    1,378.00€
    1mL*10mM (DMSO)
    264.00€
  • SPA107

    CAS:
    SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.
    Formula:C31H48N4O4
    Color and Shape:Solid
    Molecular weight:540.74

    Ref: TM-T203520

    10mg
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    50mg
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  • Tubulin polymerization-IN-55

    CAS:
    Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.
    Formula:C22H24N2O4
    Purity:98.68%
    Color and Shape:Soild
    Molecular weight:380.44

    Ref: TM-T77728

    1mg
    47.00€
    5mg
    92.00€
    10mg
    145.00€
    25mg
    235.00€
    50mg
    350.00€
    100mg
    515.00€
  • Tubulin polymerization-IN-47

    CAS:
    Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer
    Formula:C22H21N3O3
    Purity:99.64%
    Color and Shape:Soild
    Molecular weight:375.42

    Ref: TM-T77651

    2mg
    35.00€
    5mg
    56.00€
    10mg
    94.00€
    25mg
    168.00€
    50mg
    260.00€
    100mg
    360.00€
    200mg
    487.00€
  • THK5351 (R enantiomer)

    CAS:
    THK5351 R enantiomer is an R enantiomer of THK5351.
    Formula:C18H18FN3O2
    Color and Shape:Solid
    Molecular weight:327.35

    Ref: TM-T39541

    10mg
    852.00€
  • Deac-SS-Biotin


    Deac-SS-Biotin is a potent antitumor compound that enters cells via biotin-mediated internalization.
    Color and Shape:Odour Solid

    Ref: TM-T82596

    5mg
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    50mg
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  • Plecstatin-1 hydrochloride


    Plecstatin-1 hydrochloride, an organoeuropium-containing anticancer agent, selectively targets the scaffolding protein plectin within tumor spheroids [1].
    Color and Shape:Odour Solid

    Ref: TM-T81442

    5mg
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    50mg
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  • RI-AG03


    RI-AG03 is an orally active peptide inhibitor capable of crossing the blood-brain barrier, targeting Tau aggregation. It effectively inhibits Tau aggregation in both in vivo and in vitro models, improving associated neurodegenerative and behavioral phenotypes. RI-AG03 is applicable in research on Tauopathies such as Alzheimer's disease.
    Formula:C104H189N49O22
    Color and Shape:Solid
    Molecular weight:2477.93

    Ref: TM-TP3004

    10mg
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    50mg
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  • PROTAC tubulin-Degrader-1


    PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.
    Color and Shape:Odour Solid

    Ref: TM-T88391

    10mg
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    50mg
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  • Tubulin inhibitor 37


    Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell
    Formula:C16H10Cl2N6O
    Color and Shape:Solid
    Molecular weight:373.2

    Ref: TM-T78772

    5mg
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    50mg
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  • Vinzolidine

    CAS:
    Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.
    Formula:C48H58ClN5O9
    Color and Shape:Solid
    Molecular weight:884.46

    Ref: TM-T88270

    10mg
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    50mg
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  • Tubulin polymerization-IN-69


    Tubulin polymerization-IN-69 (compound 6c) exhibits significant inhibition of microtubule assembly in vitro, with an inhibition rate of 78.3% and an IC50 value of 6.53 μM. It rapidly induces apoptosis and G2/M phase cell cycle arrest in MCF-7 cells.
    Color and Shape:Odour Solid

    Ref: TM-T200641

    10mg
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    50mg
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  • MT189

    CAS:
    MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.
    Formula:C21H18FN3O2
    Purity:98.52%
    Color and Shape:Soild
    Molecular weight:363.38

    Ref: TM-T60129

    2mg
    34.00€
    5mg
    55.00€
    10mg
    85.00€
    25mg
    155.00€
    50mg
    215.00€
    100mg
    315.00€
    200mg
    432.00€
  • Tubulin polymerization-IN-48


    Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.
    Formula:C20H15Cl2N3O
    Color and Shape:Solid
    Molecular weight:384.26

    Ref: TM-T79645

    5mg
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    50mg
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  • Tubulin polymerization-IN-53


    Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.
    Color and Shape:Odour Solid

    Ref: TM-T80923

    5mg
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    50mg
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  • Microtubule stabilizing agent-1


    Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [
    Formula:C45H55NO13
    Color and Shape:Solid
    Molecular weight:817.92

    Ref: TM-T79508

    5mg
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    50mg
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  • TTBK1-IN-2

    CAS:

    TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.

    Formula:C18H13ClN4O
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:336.77

    Ref: TM-T60086

    1mg
    81.00€
    5mg
    168.00€
    10mg
    240.00€
    25mg
    399.00€
    50mg
    567.00€
    100mg
    758.00€
    200mg
    1,017.00€
  • Antiproliferative agent-66


    Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.
    Formula:C18H15N3S
    Color and Shape:Solid
    Molecular weight:305.397

    Ref: TM-T205199

    10mg
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    50mg
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  • TBL-100


    TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1100

    1mg
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    5mg
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  • Tubulin/PARP-IN-1


    Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 μM for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.
    Formula:C19H13FO3
    Molecular weight:308.08487

    Ref: TM-T208327

    10mg
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    50mg
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  • Alestramustine

    CAS:
    Alestramustine: a cancer drug that targets microtubules in estrogen receptor-positive cells, impeding cell division.
    Formula:C26H36Cl2N2O4
    Color and Shape:Solid
    Molecular weight:511.48

    Ref: TM-T25043

    25mg
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    50mg
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    100mg
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  • Tubulin inhibitor 48

    CAS:
    Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.
    Formula:C21H22N4O
    Color and Shape:Solid
    Molecular weight:346.43

    Ref: TM-T203059

    10mg
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    50mg
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  • Larotaxel dihydrate

    CAS:
    Larotaxel dihydrate possesses antineoplastic activity.
    Formula:C45H57NO16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:867.93

    Ref: TM-T25631

    25mg
    1,369.00€
  • TNIR7-1A

    CAS:
    TNIR7-1A is a fused cycloheptatriene-BODIPY derivative that is optimized for near-infrared (NIR) imaging characteristics (Ex/Em = 600/774 nm in PBS) and exhibits high affinity and specificity for neurofibrillary tangles (NFT) in vitro. Additionally, TNIR7-1A can effectively penetrate the blood-brain barrier.
    Formula:C23H20BF2N3
    Color and Shape:Solid
    Molecular weight:387.23

    Ref: TM-T203140

    10mg
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    50mg
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  • Microtubule destabilizing agent-1

    CAS:
    Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.
    Formula:C22H26N4O4
    Color and Shape:Solid
    Molecular weight:410.47

    Ref: TM-T74166

    5mg
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    50mg
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  • Aβ-IN-1 TFA


    Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.
    Formula:C37H50F3NO2
    Purity:99.82%
    Color and Shape:Soild
    Molecular weight:597.79

    Ref: TM-T63208L

    1mg
    175.00€
  • Bifidenone

    CAS:
    Bifidenone is an effective tubulin polymerization inhibitor.
    Formula:C21H26O5
    Color and Shape:Solid
    Molecular weight:358.43

    Ref: TM-T25152

    25mg
    2,448.00€
    50mg
    3,222.00€
    100mg
    4,410.00€
  • Tubulin polymerization-IN-44


    Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it
    Formula:C19H15Cl2N3O3S
    Color and Shape:Solid
    Molecular weight:436.31

    Ref: TM-T79532

    5mg
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    50mg
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  • Epothilone F

    CAS:
    Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.
    Formula:C27H41NO7S
    Color and Shape:Solid
    Molecular weight:523.68

    Ref: TM-T31657

    100mg
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    500mg
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  • Cy5-Paclitaxel


    Cy5-Paclitaxel is a Cy5-labeled paclitaxel conjugate. Cy5 is a cyanine dye (with an approximate wavelength of 662 nm) utilized in molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization, causing mitotic arrest and apoptotic death. It also induces autophagy.
    Formula:C93H104N4O16
    Color and Shape:Solid
    Molecular weight:1533.84

    Ref: TM-T203411

    10mg
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    50mg
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  • T-900607

    CAS:

    T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.

    Formula:C14H10F5N3O4S
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:411.3

    Ref: TM-T68147

    1mg
    89.00€
    5mg
    172.00€
    10mg
    254.00€
    25mg
    393.00€
    50mg
    542.00€
    100mg
    725.00€
    200mg
    979.00€
  • 7-Epi-docetaxel

    CAS:
    7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.
    Formula:C43H53NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:807.88

    Ref: TM-TQ0247

    1mg
    545.00€
    5mg
    To inquire
    10mg
    To inquire
  • OncoFAP-GlyPro-MMAE

    CAS:
    OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. It is composed of the FAP ligand OncoFAP, a microtubule inhibitor (MMAE), and a linker. OncoFAP-GlyPro-MMAE can be utilized in cancer research, including studies on renal cancer.
    Formula:C102H141F2N19O27S
    Color and Shape:Solid
    Molecular weight:2135.38

    Ref: TM-T212205

    10mg
    To inquire
    50mg
    To inquire
  • Anticancer agent 270


    Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.
    Color and Shape:Odour Solid

    Ref: TM-T206688

    10mg
    To inquire
    50mg
    To inquire
  • 10-Oxo Docetaxel

    CAS:
    10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.
    Formula:C43H51NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.874

    Ref: TM-TQ0142

    5mg
    807.00€
    10mg
    1,468.00€
  • Colchicine, N-deacetyl-10-thio-

    CAS:
    Colchicine, N-deacetyl-10-thio- is a biochemical.
    Formula:C20H23NO4S
    Color and Shape:Solid
    Molecular weight:373.47

    Ref: TM-T31000

    100mg
    To inquire
    500mg
    To inquire
  • KGP591


    KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure
    Formula:C24H21NO5
    Color and Shape:Solid
    Molecular weight:403.43

    Ref: TM-T79408

    5mg
    To inquire
    50mg
    To inquire
  • Tubulin polymerization-IN-51


    Tubulin Polymerization-IN-51 (compound 7u) serves as a tubulin polymerization inhibitor, exhibiting an IC50 range of 2.55 - 17.89μM against SK-Mel-28 cells, and
    Color and Shape:Odour Solid

    Ref: TM-T80924

    5mg
    To inquire
    50mg
    To inquire
  • Tubulin polymerization-IN-50


    Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell
    Formula:C24H20FN3O3
    Color and Shape:Solid
    Molecular weight:417.43

    Ref: TM-T79429

    5mg
    To inquire
    50mg
    To inquire
  • Indicine N-oxide

    CAS:
    Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.
    Formula:C15H25NO6
    Color and Shape:Solid
    Molecular weight:315.37

    Ref: TM-T40519

    25mg
    1,369.00€
  • Modified MMAF

    CAS:
    Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.
    Formula:C45H73N7O8
    Color and Shape:Solid
    Molecular weight:840.1

    Ref: TM-T74177

    5mg
    To inquire
    50mg
    To inquire
  • T-808

    CAS:
    T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.
    Formula:C17H19FN4
    Color and Shape:Solid
    Molecular weight:298.36

    Ref: TM-T34766

    25mg
    1,369.00€
  • Tubulin inhibitor 36


    Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,
    Formula:C16H13ClN6S
    Color and Shape:Solid
    Molecular weight:356.83

    Ref: TM-T78771

    5mg
    To inquire
    50mg
    To inquire
  • Tubulin inhibitor 21


    Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.
    Formula:C28H25N3O4S
    Color and Shape:Solid
    Molecular weight:499.58

    Ref: TM-T73832

    5mg
    To inquire
    50mg
    To inquire
  • ALB-109564 dihydrochloride

    CAS:
    ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.
    Formula:C47H62Cl2N4O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:929.99

    Ref: TM-T25025

    25mg
    1,369.00€
  • Combretastatin A-1 phosphate tetrasodium

    CAS:
    OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.
    Formula:C18H18Na4O12P2
    Color and Shape:Solid
    Molecular weight:580.24

    Ref: TM-T40367

    100mg
    To inquire
    500mg
    To inquire
  • PM050489

    CAS:
    PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.
    Formula:C31H44ClN3O7
    Color and Shape:Solid
    Molecular weight:606.15

    Ref: TM-T75521

    5mg
    To inquire
    50mg
    To inquire
  • Phomopsinamine

    CAS:
    Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).
    Formula:C32H43ClN6O8
    Color and Shape:Solid
    Molecular weight:675.17

    Ref: TM-T36855

    1mg
    1,421.00€
  • Tubulin polymerization-IN-46


    Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast
    Formula:C22H25NO6
    Color and Shape:Solid
    Molecular weight:399.44

    Ref: TM-T79629

    5mg
    To inquire
    50mg
    To inquire
  • Anti-α-Tubulin Antibody, AF555 conjugate


    Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the
    Color and Shape:Solid

    Ref: TM-T75383

    5mg
    To inquire
    50mg
    To inquire
  • 7-Epi-10-oxo-docetaxel

    CAS:
    7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.
    Formula:C43H51NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.86

    Ref: TM-T19163

    1mg
    572.00€
    5mg
    2,495.00€
  • Tubulin polymerization-IN-49


    Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell
    Formula:C20H24O5
    Color and Shape:Solid
    Molecular weight:344.4

    Ref: TM-T79887

    5mg
    To inquire
    50mg
    To inquire
  • 20-O-Demethyl-AP3

    CAS:
    20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.
    Formula:C31H41ClN2O9
    Color and Shape:Solid
    Molecular weight:621.12

    Ref: TM-T40838

    25mg
    1,369.00€
  • Vinflunine Tartrate

    CAS:
    Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.
    Formula:C45H54F2N4O8·xC4H6O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:967.02

    Ref: TM-T6722

    2mg
    To inquire
    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    1mL*10mM (DMSO)
    To inquire
  • Tubulin inhibitor 38


    Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell
    Formula:C17H13ClN6OS
    Color and Shape:Solid
    Molecular weight:384.84

    Ref: TM-T78773

    5mg
    To inquire
    50mg
    To inquire
  • Anticancer agent 139


    Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high
    Formula:C16H12F3N3O
    Color and Shape:Solid
    Molecular weight:319.28

    Ref: TM-T78780

    5mg
    To inquire
    50mg
    To inquire
  • Phomopsin A

    CAS:
    Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.
    Formula:C36H45ClN6O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:789.23

    Ref: TM-T12448

    100mg
    To inquire
    500mg
    To inquire
  • Tubulin polymerization-IN-78


    Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.
    Color and Shape:Odour Solid

    Ref: TM-T206844

    10mg
    To inquire
    50mg
    To inquire
  • Ceratamine A

    CAS:

    Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.

    Formula:C17H16Br2N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.14

    Ref: TM-T10763

    25mg
    1,444.00€
  • Tubulin inhibitor 50


    Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.
    Formula:C16H10ClFN2O2
    Color and Shape:Solid
    Molecular weight:316.04148

    Ref: TM-T207405

    10mg
    To inquire
    50mg
    To inquire
  • Microtubule-associated protein tau (26-44)


    Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.

    Formula:C83H127N25O34S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2051.11

    Ref: TM-TP1420

    1mg
    106.00€
    5mg
    308.00€
    10mg
    432.00€
    50mg
    1,044.00€
  • Vinflunine

    CAS:
    Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
    Formula:C45H54F2N4O8
    Color and Shape:Solid
    Molecular weight:816.93

    Ref: TM-T7594

    25mg
    1,369.00€
  • Sudocetaxel

    CAS:
    Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.
    Formula:C48H59NO16
    Color and Shape:Solid
    Molecular weight:905.98

    Ref: TM-T74418

    5mg
    To inquire
    50mg
    To inquire
  • Ombrabulin hydrochloride

    CAS:
    Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and
    Formula:C21H27ClN2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.9

    Ref: TM-T16386

    2mg
    52.00€
  • Tirbanibulin dihydrochloride

    CAS:
    Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
    Formula:C26H31Cl2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.45

    Ref: TM-T15674

    2mg
    37.00€
  • PhosTAC7

    CAS:
    PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.
    Formula:C58H87ClN2O17
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:1119.77

    Ref: TM-T77934

    1mg
    260.00€
    5mg
    620.00€
    10mg
    1,063.00€
    25mg
    2,088.00€
    50mg
    3,357.00€
    100mg
    4,438.00€
  • TTBK1-IN-1

    CAS:
    TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.
    Formula:C18H19N5O2
    Color and Shape:Solid
    Molecular weight:337.38

    Ref: TM-T40348

    1mg
    120.00€
    2mg
    170.00€
  • Trifluralin

    CAS:
    Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.
    Formula:C13H16F3N3O4
    Purity:99.84%
    Color and Shape:Yellow-Orange Crystalline Solid
    Molecular weight:335.28

    Ref: TM-T17163

    200mg
    35.00€
    500mg
    52.00€
    1mL*10mM (DMSO)
    44.00€
  • colchiceine

    CAS:
    colchiceine has a wide range of applications in life science related research.
    Formula:C21H23NO6
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:385.41

    Ref: TM-TC0037

    1mg
    66.00€
    5mg
    126.00€
    10mg
    178.00€
    25mg
    303.00€
  • BSc3094

    CAS:
    BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.
    Formula:C17H12N6O3S
    Color and Shape:Solid
    Molecular weight:380.38

    Ref: TM-T41102

    2mg
    111.00€
  • Oryzalin

    CAS:
    Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.
    Formula:C12H18N4O6S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:346.36

    Ref: TM-T65381

    25mg
    37.00€
    50mg
    51.00€
    100mg
    67.00€
    1mL*10mM (DMSO)
    52.00€
  • Amiprofos methyl

    CAS:
    Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.
    Formula:C11H17N2O4PS
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:304.30

    Ref: TM-T35486

    5mg
    37.00€
    10mg
    58.00€
    25mg
    109.00€
    50mg
    175.00€
    100mg
    262.00€
    200mg
    388.00€
  • Avanbulin

    CAS:
    Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.
    Formula:C20H17N7O2
    Color and Shape:Solid
    Molecular weight:387.39

    Ref: TM-T21317

    2mg
    48.00€
    5mg
    71.00€
    1mL*10mM (DMSO)
    78.00€
  • 4-Isopropoxybenzoic acid

    CAS:
    4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.
    Formula:C10H12O3
    Purity:99.88%
    Color and Shape:White To Off-White Powder
    Molecular weight:180.2

    Ref: TM-T24977

    1g
    58.00€
    5g
    124.00€
    10g
    178.00€
    500mg
    49.00€
    1mL*10mM (DMSO)
    33.00€
  • Valecobulin

    CAS:
    Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.
    Formula:C26H28N6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:536.6

    Ref: TM-T13278L

    5mg
    268.00€
    25mg
    888.00€
    50mg
    1,224.00€
    100mg
    1,674.00€
  • Vindesine sulfate

    CAS:
    Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.
    Formula:C43H57N5O11S
    Purity:97.51%
    Color and Shape:Amorphous Solid
    Molecular weight:852

    Ref: TM-T22455

    5mg
    89.00€
    20mg
    197.00€
    1mL*10mM (DMSO)
    To inquire
  • Spastazoline

    CAS:
    Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).
    Formula:C20H30N8
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:382.51

    Ref: TM-T8513

    1mg
    34.00€
    5mg
    71.00€
    10mg
    105.00€
    25mg
    205.00€
    50mg
    306.00€
    100mg
    440.00€
    200mg
    612.00€
    1mL*10mM (DMSO)
    78.00€
  • Albendazole sulfoxide

    CAS:
    Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
    Formula:C12H15N3O3S
    Purity:97.29%
    Color and Shape:White To Off-White Powder
    Molecular weight:281.33

    Ref: TM-T6372

    1g
    58.00€
    500mg
    46.00€
    1mL*10mM (DMSO)
    33.00€