Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 274 products of "Microtubule Associated"
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Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purity:> 95% - >95.0% (SDS-PAGE)Color and Shape:LiquidMolecular weight:145.3 kDaTubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37Ref: TM-T14694
1mg79.00€5mg152.00€10mg215.00€25mg351.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)167.00€Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Purity:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.92 kDaVerubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Ref: TM-T13298
5mg52.00€10mg73.00€25mg138.00€50mg200.00€100mg284.00€200mg411.00€1mL*10mM (DMSO)52.00€Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99%Color and Shape:SolidMolecular weight:527.63Ref: TM-T15675
2mg35.00€5mg52.00€10mg66.00€25mg119.00€50mg230.00€100mg394.00€200mg532.00€1mL*10mM (DMSO)62.00€Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.89Tubulin inhibitor 50
Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.Formula:C16H10ClFN2O2Color and Shape:SolidMolecular weight:316.04148Antiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Formula:C18H15N3SColor and Shape:SolidMolecular weight:305.397AADvac 1 TFA
AADvac 1 TFA is an active tau peptide vaccine utilized in Alzheimer's disease research. It is formed by conjugating the regulatory peptide 294KDNIKHVPGGGS305, which drives tau oligomerization, with keyhole limpet hemocyanin (KLH), and is formulated with aluminum hydroxide.Microtubule stabilizing agent-1
Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [Formula:C45H55NO13Color and Shape:SolidMolecular weight:817.92Anticancer agent 139
Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating highFormula:C16H12F3N3OColor and Shape:SolidMolecular weight:319.28PROTAC tubulin-Degrader-1
PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.Color and Shape:Odour SolidVinzolidine
CAS:Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.Formula:C48H58ClN5O9Color and Shape:SolidMolecular weight:884.46Anhydrovinblastine sulfate
Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.Formula:C46H60N4O16S2Molecular weight:988.34457Tubulin inhibitor 37
Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cellFormula:C16H10Cl2N6OColor and Shape:SolidMolecular weight:373.2Tubulin inhibitor 45
Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.Formula:C19H18N2O2SMolecular weight:338.1089KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structureFormula:C24H21NO5Color and Shape:SolidMolecular weight:403.43Diminutol
CAS:Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Formula:C19H26N6OSColor and Shape:SolidMolecular weight:386.51Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Color and Shape:Odour SolidTubulin polymerization-IN-49
Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cellFormula:C20H24O5Color and Shape:SolidMolecular weight:344.47-Epi-docetaxel
CAS:7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.Formula:C43H53NO14Purity:98%Color and Shape:SolidMolecular weight:807.88Anticancer agent 270
Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.Color and Shape:Odour SolidTubulin polymerization-IN-53
Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.Color and Shape:Odour SolidAnti-α-Tubulin Antibody, AF555 conjugate
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for theColor and Shape:SolidEpothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68Tubulin inhibitor 21
Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.Formula:C28H25N3O4SColor and Shape:SolidMolecular weight:499.58Phomopsinamine
CAS:Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Formula:C32H43ClN6O8Color and Shape:SolidMolecular weight:675.1710-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.874PM050489
CAS:PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.Formula:C31H44ClN3O7Color and Shape:SolidMolecular weight:606.15Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Formula:C18H18Na4O12P2Color and Shape:SolidMolecular weight:580.24TBL-100
TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.Color and Shape:Odour LiquidTubulin polymerization-IN-44
Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making itFormula:C19H15Cl2N3O3SColor and Shape:SolidMolecular weight:436.31Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formula:C45H54F2N4O8·xC4H6O6Purity:98%Color and Shape:SolidMolecular weight:967.02Ref: TM-T6722
2mgTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire1mL*10mM (DMSO)To inquireTubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFormula:C22H25NO6Color and Shape:SolidMolecular weight:399.447-Epi-10-oxo-docetaxel
CAS:7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.86T-808
CAS:T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.Formula:C17H19FN4Color and Shape:SolidMolecular weight:298.36Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFormula:C17H13ClN6OSColor and Shape:SolidMolecular weight:384.8420-O-Demethyl-AP3
CAS:20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.Formula:C31H41ClN2O9Color and Shape:SolidMolecular weight:621.12Ceratamine A
CAS:Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.
Formula:C17H16Br2N4O2Purity:98%Color and Shape:SolidMolecular weight:468.14Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Formula:C36H45ClN6O12Purity:98%Color and Shape:SolidMolecular weight:789.23Microtubule destabilizing agent-1
CAS:Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Formula:C22H26N4O4Color and Shape:SolidMolecular weight:410.47Cys-McMMAF
CAS:Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.Formula:C52H83N7O13SColor and Shape:SolidMolecular weight:1046.32Dihydrocephalomannine
CAS:Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.Formula:C45H55NO14Purity:98%Color and Shape:SolidMolecular weight:833.928Pironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45Sudocetaxel
CAS:Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.Formula:C48H59NO16Color and Shape:SolidMolecular weight:905.98Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formula:C22H21N3O3Purity:99.99%Color and Shape:SolidMolecular weight:375.42Modified MMAF
CAS:Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.Formula:C45H73N7O8Color and Shape:SolidMolecular weight:840.1ALB-109564 dihydrochloride
CAS:ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.Formula:C47H62Cl2N4O9SPurity:98%Color and Shape:SolidMolecular weight:929.99
