Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 261 products of "Microtubule Associated"
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AC 7739
CAS:<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Formula:C18H22ClNO4Purity:99.38% - 99.55%Color and Shape:SoildMolecular weight:351.83Tubulin inhibitor 6
CAS:<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85DM4
CAS:<p>DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.</p>Formula:C38H54ClN3O10SPurity:98.15%Color and Shape:SolidMolecular weight:780.37Tirbanibulin Mesylate
CAS:<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formula:C27H33N3O6SPurity:99%Color and Shape:SolidMolecular weight:527.63Zagotenemab
CAS:<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Purity:95% - > 95%Color and Shape:LiquidMolecular weight:145.3 kDaVerubulin hydrochloride
CAS:<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Formula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Entasobulin
CAS:<p>Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.</p>Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.89BNC105
CAS:<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37Bepranemab
CAS:<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Purity:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Color and Shape:LiquidTilavonemab
CAS:<p>Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.</p>Purity:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:LiquidTubulin inhibitor 45
<p>Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.</p>Formula:C19H18N2O2SMolecular weight:338.1089Modified MMAF
CAS:<p>Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.</p>Formula:C45H73N7O8Color and Shape:SolidMolecular weight:840.1Tubulin inhibitor 50
<p>Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.</p>Formula:C16H10ClFN2O2Color and Shape:SolidMolecular weight:316.04148Vinzolidine
CAS:<p>Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.</p>Formula:C48H58ClN5O9Color and Shape:SolidMolecular weight:884.46PM050489
CAS:<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Formula:C31H44ClN3O7Color and Shape:SolidMolecular weight:606.15Antiproliferative agent-66
<p>Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.</p>Formula:C18H15N3SColor and Shape:SolidMolecular weight:305.397Tubulin/PARP-IN-1
<p>Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 μM for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.</p>Formula:C19H13FO3Molecular weight:308.08487KIF18A-IN-12
CAS:<p>KIF18A-IN-12 (compound 9), a potent KIF18A inhibitor, exhibits an IC 50 of 45.54 nM and is utilized in cancer research.</p>Formula:C30H39F2N5O4SColor and Shape:SolidMolecular weight:603.72Phomopsin A
CAS:<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formula:C36H45ClN6O12Purity:98%Color and Shape:SolidMolecular weight:789.2320-O-Demethyl-AP3
CAS:<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Formula:C31H41ClN2O9Color and Shape:SolidMolecular weight:621.12Tubulin polymerization-IN-49
<p>Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell</p>Formula:C20H24O5Color and Shape:SolidMolecular weight:344.4Tubulin polymerization-IN-53
<p>Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.</p>Color and Shape:Odour SolidTubulin polymerization-IN-44
<p>Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it</p>Formula:C19H15Cl2N3O3SColor and Shape:SolidMolecular weight:436.31Dihydrocephalomannine
CAS:<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Formula:C45H55NO14Purity:98%Color and Shape:SolidMolecular weight:833.928Anti-α-Tubulin Antibody, AF555 conjugate
<p>Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the</p>Color and Shape:SolidAnticancer agent 270
<p>Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.</p>Color and Shape:Odour Solid7-Epi-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Formula:C43H53NO14Purity:98%Color and Shape:SolidMolecular weight:807.88Epothilone F
CAS:<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Formula:C28H25N3O4SColor and Shape:SolidMolecular weight:499.58PROTAC tubulin-Degrader-1
<p>PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.</p>Color and Shape:Odour SolidDiminutol
CAS:<p>Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.</p>Formula:C19H26N6OSColor and Shape:SolidMolecular weight:386.51Anticancer agent 139
<p>Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high</p>Formula:C16H12F3N3OColor and Shape:SolidMolecular weight:319.28Tubulin inhibitor 37
<p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>Formula:C16H10Cl2N6OColor and Shape:SolidMolecular weight:373.2Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Formula:C24H21NO5Color and Shape:SolidMolecular weight:403.43Microtubule stabilizing agent-1
<p>Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [</p>Formula:C45H55NO13Color and Shape:SolidMolecular weight:817.92T-808
CAS:<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Formula:C17H19FN4Color and Shape:SolidMolecular weight:298.36Tubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formula:C22H25NO6Color and Shape:SolidMolecular weight:399.44Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formula:C83H127N25O34SPurity:98%Color and Shape:SolidMolecular weight:2051.11Tubulin polymerization-IN-78
<p>Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.</p>Color and Shape:Odour Solid7-Epi-10-oxo-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.86Tubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Formula:C17H13ClN6OSColor and Shape:SolidMolecular weight:384.84Ceratamine A
CAS:<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Formula:C17H16Br2N4O2Purity:98%Color and Shape:SolidMolecular weight:468.14Microtubule destabilizing agent-1
CAS:<p>Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.</p>Formula:C22H26N4O4Color and Shape:SolidMolecular weight:410.47Tubulin polymerization-IN-48
<p>Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.</p>Formula:C20H15Cl2N3OColor and Shape:SolidMolecular weight:384.26Cys-McMMAF
CAS:<p>Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.</p>Formula:C52H83N7O13SColor and Shape:SolidMolecular weight:1046.32Tubulin inhibitor 24
CAS:<p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>Formula:C22H21N3O3Purity:99.99%Color and Shape:SolidMolecular weight:375.42Pironetin
CAS:<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45Sudocetaxel
CAS:<p>Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.</p>Formula:C48H59NO16Color and Shape:SolidMolecular weight:905.98Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Formula:C24H20FN3O3Color and Shape:SolidMolecular weight:417.43
