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c-Myc

c-Myc

c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.

Found 69 products of "c-Myc"

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  • MYCi361
    Targetmol
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    MYCi361

    CAS:
    <p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>
    Formula:C26H16ClF9N2O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:594.86

    Ref: TM-T12132

  • MYCi975
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    MYCi975

    CAS:
    <p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>
    Formula:C25H16Cl2F6N2O2
    Purity:99.3% - 99.82%
    Color and Shape:Solid
    Molecular weight:561.3

    Ref: TM-T12133

  • Eragidomide
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    Eragidomide

    CAS:
    <p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>
    Formula:C22H18ClF2N3O4
    Purity:97.51% - 99.63%
    Color and Shape:Solid
    Molecular weight:461.85

    Ref: TM-T10765

  • Ceramides Mixture
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    Ceramides Mixture

    CAS:
    <p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>
    Formula:C36H71NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:581.967

    Ref: TM-T10760

  • APTO-253
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    APTO-253

    CAS:
    <p>APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.</p>
    Formula:C22H14FN5
    Purity:98.73%
    Color and Shape:Solid
    Molecular weight:367.38

    Ref: TM-T10352

  • MYCMI-6
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    MYCMI-6

    CAS:
    <p>MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.</p>
    Formula:C20H19N7O
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:373.41

    Ref: TM-T12134

  • KJ Pyr 9
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    KJ Pyr 9

    CAS:
    <p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>
    Formula:C22H15N3O4
    Purity:99.56% - ≥98%
    Color and Shape:Solid
    Molecular weight:385.37

    Ref: TM-T15665

  • FIDAS-3
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    FIDAS-3

    CAS:
    <p>FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities</p>
    Formula:C16H15F2N
    Purity:97.75%
    Color and Shape:Solid
    Molecular weight:259.29

    Ref: TM-T11284

  • FIDAS-5
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    FIDAS-5

    CAS:
    <p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>
    Formula:C15H13ClFN
    Purity:97.66% - 98.3%
    Color and Shape:Solid
    Molecular weight:261.72

    Ref: TM-T11285

  • Saxagliptin hydrate
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    Saxagliptin hydrate

    CAS:
    <p>Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).</p>
    Formula:C18H25N3O2·H2O
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:333.43

    Ref: TM-T0178

  • MYC-IN-2
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    MYC-IN-2

    CAS:
    <p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>
    Formula:C25H17N3O2S
    Color and Shape:Solid
    Molecular weight:423.49

    Ref: TM-T39751

  • RA-V
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    RA-V

    <p>RA-V is a natural product that can be used as a reference standard.</p>
    Formula:C160H202N24O41
    Color and Shape:Solid
    Molecular weight:3117.5

    Ref: TM-T124482

  • CymitQuimica logo
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    c-Myc inhibitor 5

    <p>DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.</p>
    Formula:C30H46N12
    Color and Shape:Solid
    Molecular weight:574.77

    Ref: TM-T74460

  • c-Myc inhibitor 10
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    c-Myc inhibitor 10

    CAS:
    <p>c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.</p>
    Formula:C28H38N6O3
    Color and Shape:Solid
    Molecular weight:506.64

    Ref: TM-T75239

  • CymitQuimica logo
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    c-Myc inhibitor 12

    <p>Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].</p>
    Formula:C22H24N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:388.47

    Ref: TM-T79439

  • CymitQuimica logo
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    MDEG-541

    <p>MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].</p>
    Formula:C35H38N4O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:658.76

    Ref: TM-T78986

  • CymitQuimica logo
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    Anti-c-myc Antibody (9E10)

    <p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-960

  • CymitQuimica logo
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    PROTAC MTP3 degrade-1

    <p>PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.</p>
    Formula:C44H38N6O8
    Color and Shape:Solid
    Molecular weight:778.27511

    Ref: TM-T207468

  • CymitQuimica logo
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    Methylcarbamyl PAF C-8

    <p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206879

  • CymitQuimica logo
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    c-Myc inhibitor 11

    <p>c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat</p>
    Formula:C20H22N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:362.43

    Ref: TM-T79438

  • CymitQuimica logo
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    CSI86

    <p>CSI86 is a PROTAC degrader targeting MYC, exhibiting antiproliferative activity (IC50: 13-18 μM).</p>
    Formula:C48H50F9N7O7S
    Color and Shape:Solid
    Molecular weight:1040

    Ref: TM-T201659

  • WBC100
    Targetmol
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    WBC100

    CAS:
    <p>WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway</p>
    Formula:C25H33NO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.53

    Ref: TM-T77939

  • Anticancer agent 263
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    Anticancer agent 263

    <p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.308

    Ref: TM-T204102

  • c-Myc inhibitor 7
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    c-Myc inhibitor 7

    CAS:
    <p>c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.</p>
    Formula:C35H30N6O5
    Color and Shape:Soild
    Molecular weight:614.65

    Ref: TM-T72040

  • Anticancer agent 84
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    Anticancer agent 84

    CAS:
    <p>Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.</p>
    Formula:C57H67N7O9
    Color and Shape:Solid
    Molecular weight:994.18

    Ref: TM-T74961

  • CymitQuimica logo
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    VGN50

    <p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>
    Formula:C121H218N46O32
    Molecular weight:2827.68453

    Ref: TM-TP3582

  • CymitQuimica logo
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    c-Myc inhibitor 13

    <p>c-Myc inhibitor13 (compound A6) is an inhibitor of c-MYC transcription. It selectively stabilizes c-MYCG4 and inhibits G4-related c-MYC transcription.</p>
    Formula:C30H39N9O
    Molecular weight:541.32776

    Ref: TM-T209418

  • Cotylenin A
    Targetmol
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    Cotylenin A

    CAS:
    <p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>
    Formula:C33H50O11
    Color and Shape:Solid
    Molecular weight:622.744

    Ref: TM-TN8969

  • H122
    Targetmol
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    H122

    <p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>
    Formula:C45H45ClFN5O8
    Color and Shape:Solid
    Molecular weight:838.319

    Ref: TM-T204932

  • PROTAC LZK-IN-1
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    PROTAC LZK-IN-1

    CAS:
    <p>PROTAC LZK-IN-1 (Compound 21A) is a PROTAC molecule that targets the degradation of LZK (leucine zipper kinase, encoded by MAP3K13). At a concentration of 10 μM, PROTAC LZK-IN-1 facilitates the degradation of LZK and inhibits the expression of p53 and c-MYC, leading to reduced viability of global head and neck squamous cell carcinoma (HNSCC) cell lines. This compound is applicable in anticancer research.</p>
    Formula:C51H64F2N10O5S
    Color and Shape:Solid
    Molecular weight:967.18

    Ref: TM-T204373

  • KL4-219A
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    KL4-219A

    <p>KL4-219A is a selective covalent degrader of the MYC, inhibiting MYC transcriptional activity and degrading MYC in a proteasome-dependent manner .</p>
    Formula:C20H24N2O2S
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:356.48

    Ref: TM-T204093

  • VPC-70063
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    VPC-70063

    CAS:
    <p>VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.</p>
    Formula:C16H12F6N2S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:378.34

    Ref: TM-T60019

  • sAJM589
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    sAJM589

    CAS:
    <p>sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.</p>
    Formula:C16H10N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:246.26

    Ref: TM-T16839

  • IRES-C11
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    IRES-C11

    CAS:
    <p>IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.</p>
    Formula:C13H11Cl2NO4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:316.14

    Ref: TM-T40419

  • Mycro 3
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    Mycro 3

    CAS:
    <p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>
    Formula:C24H17ClF2N6O4
    Purity:99.51% - 99.61%
    Color and Shape:Solid
    Molecular weight:526.88

    Ref: TM-T4367

  • Saxagliptin
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    Saxagliptin

    CAS:
    <p>Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.</p>
    Formula:C18H25N3O2
    Purity:99.17% - 99.95%
    Color and Shape:Solid
    Molecular weight:315.41

    Ref: TM-T6203

  • (S)-10-Hydroxycamptothecin
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    (S)-10-Hydroxycamptothecin

    CAS:
    <p>(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.</p>
    Formula:C20H16N2O5
    Purity:99.09% - 99.81%
    Color and Shape:Solid
    Molecular weight:364.35

    Ref: TM-T2764

  • Mollugin
    Targetmol
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    Mollugin

    CAS:
    <p>Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.</p>
    Formula:C17H16O4
    Purity:99.87% - ≥95%
    Color and Shape:Solid
    Molecular weight:284.31

    Ref: TM-T3673

  • ML327
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    ML327

    CAS:
    <p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>
    Formula:C19H18N4O4
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:366.37

    Ref: TM-T4252

  • 10074-G5
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    10074-G5

    CAS:
    <p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>
    Formula:C18H12N4O3
    Purity:99.51% - 99.67%
    Color and Shape:Solid
    Molecular weight:332.31

    Ref: TM-T3686

  • NNK
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    NNK

    CAS:
    <p>NNK is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.Cost-effective and quality-assured.</p>
    Formula:C10H13N3O2
    Purity:99.63% - 99.92%
    Color and Shape:Solid
    Molecular weight:207.23

    Ref: TM-T20533

  • Lusianthridin
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    Lusianthridin

    CAS:
    <p>Lusianthridin is a natural product from Dendrobium venustum.</p>
    Formula:C15H14O3
    Purity:98.49%
    Color and Shape:Solid
    Molecular weight:242.27

    Ref: TM-TN1892

  • Agrimol B
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    Agrimol B

    CAS:
    <p>1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.</p>
    Formula:C37H46O12
    Purity:99.06% - ≥95%
    Color and Shape:Solid
    Molecular weight:682.75

    Ref: TM-T4S1173

  • 10058-F4
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    10058-F4

    CAS:
    <p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest &amp; apoptosis.</p>
    Formula:C12H11NOS2
    Purity:98% - 99.87%
    Color and Shape:Solid
    Molecular weight:249.35

    Ref: TM-T3048

  • APTO-253 HCl
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    APTO-253 HCl

    CAS:
    <p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>
    Formula:C22H15ClFN5
    Color and Shape:Solid
    Molecular weight:403.84

    Ref: TM-T70273

  • 10074-A4
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    10074-A4

    CAS:
    <p>10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from</p>
    Formula:C18H14Cl2N2O3S
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:409.29

    Ref: TM-T9628

  • Artemisitene
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    Artemisitene

    CAS:
    <p>Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.</p>
    Formula:C15H20O5
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:280.32

    Ref: TM-T21065

  • NY2267
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    NY2267

    CAS:
    <p>NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl</p>
    Formula:C38H43N3O6
    Purity:99.16% - 99.27%
    Color and Shape:Solid
    Molecular weight:637.76

    Ref: TM-T9093

  • Idarubicin hydrochloride
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    Idarubicin hydrochloride

    CAS:
    <p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>
    Formula:C26H27NO9·HCl
    Purity:98.91% - 99.96%
    Color and Shape:Solid
    Molecular weight:533.95

    Ref: TM-T6010

  • BTYNB
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    BTYNB

    CAS:
    <p>BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.</p>
    Formula:C12H9BrN2OS
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:309.18

    Ref: TM-T9033

  • EN4
    Targetmol
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    EN4

    CAS:
    <p>EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.</p>
    Formula:C25H24N2O4
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:416.47

    Ref: TM-T9061

  • PARL Protein, Human, Recombinant (Myc)
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    PARL Protein, Human, Recombinant (Myc)

    <p>Required for the control of apoptosis during postnatal growth.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:37.8 kDa (predicted)

    Ref: TM-TMPH-01898

  • ACOX1 Protein, Mouse, Recombinant (Myc)
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    ACOX1 Protein, Mouse, Recombinant (Myc)

    <p>Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:76.2 kDa (predicted)

    Ref: TM-TMPH-02825

  • 2-5A-dependent Rnase Protein, Human, Recombinant (Myc)
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    2-5A-dependent Rnase Protein, Human, Recombinant (Myc)

    <p>2-5A-dependent Rnase Protein, Human, Recombinant (Myc) is expressed in E.</p>
    Purity:85% - 85%
    Color and Shape:Lyophilized Powder
    Molecular weight:85.1 kDa (predicted)

    Ref: TM-TMPH-00847

  • c-Myc inhibitor 9
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    c-Myc inhibitor 9

    CAS:
    <p>c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.</p>
    Formula:C27H31N5OS
    Color and Shape:Solid
    Molecular weight:473.63

    Ref: TM-T72620

  • RK-9123016
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    RK-9123016

    CAS:
    <p>RK-9123016 is a SIRT2 inhibitor.</p>
    Formula:C16H18N6O3S
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:374.42

    Ref: TM-T28543

  • FUBP1-IN-2
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    FUBP1-IN-2

    CAS:
    <p>FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.</p>
    Formula:C26H26ClN3O4
    Color and Shape:Solid
    Molecular weight:479.96

    Ref: TM-T73166

  • KSI-3716
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    KSI-3716

    CAS:
    <p>KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.</p>
    Formula:C17H11BrCl2N2O2
    Purity:98.94%
    Color and Shape:Solid
    Molecular weight:426.09

    Ref: TM-T11783

  • BI8622
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    BI8622

    CAS:
    <p>BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.</p>
    Formula:C25H26N6O
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:426.51

    Ref: TM-T14568

  • VPC-70619
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    VPC-70619

    CAS:
    <p>VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.</p>
    Formula:C16H8ClF3N4O
    Color and Shape:Solid
    Molecular weight:364.71

    Ref: TM-T9731

  • c-Myc inhibitor 8
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    c-Myc inhibitor 8

    CAS:
    <p>c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.</p>
    Formula:C19H12BrClF3NO3S2
    Color and Shape:Solid
    Molecular weight:538.79

    Ref: TM-T72619

  • m-Se3
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    m-Se3

    CAS:
    <p>m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].</p>
    Formula:C29H23IN2Se
    Purity:98%
    Color and Shape:Solid
    Molecular weight:605.37

    Ref: TM-T79872

  • SYHA1815
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    SYHA1815

    CAS:
    <p>SYHA1815, an orally active RET inhibitor (IC50=0.9 nmol/L), demonstrates antitumor activity. It exhibits greater selectivity for RET over KDR (IC50=15.9 nmol/L). SYHA1815 operates by downregulating c-Myc, arresting the G1 cell cycle, and inhibiting RET-driven cell proliferation.</p>
    Formula:C27H26ClF4N5O
    Color and Shape:Solid
    Molecular weight:547.98

    Ref: TM-T200124

  • KI-CDK9d-32
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    KI-CDK9d-32

    CAS:
    <p>KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.</p>
    Formula:C39H45N9O4
    Color and Shape:Solid
    Molecular weight:703.83

    Ref: TM-T207184

  • CymitQuimica logo
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    c-Myc inhibitor 4

    <p>Potent oral c-Myc inhibitor 4 reduces the proto-oncogene linked to tumor development.</p>
    Formula:C26H33FN6O3
    Color and Shape:Solid
    Molecular weight:496.58

    Ref: TM-T63359

  • BRD4 Inhibitor-40
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    BRD4 Inhibitor-40

    CAS:
    <p>BRD4 Inhibitor-40 (Compound 23) functions as an inhibitor of BRD, effectively targeting BRD4-BD1, BRD4-BD2, BRD2-BD1, and BRD2-BD2, with IC50 values of 16.1, 142.18, 29.35, and 302.35 nM, respectively. It modulates the expression of c-Myc and p21, induces cell cycle arrest in the G1 phase, and inhibits Pkd1-deficient (PN) renal cystic epithelial cells. Additionally, it prevents renal cyst formation in both Madin-Darby canine kidney and embryonic kidney cyst models, and demonstrates renal cyst inhibition activity in mouse models.</p>
    Formula:C27H32N8O
    Color and Shape:Solid
    Molecular weight:484.596

    Ref: TM-T205510

  • MY05
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    MY05

    CAS:
    <p>MY05 selectively targets c-MYC within cells and disrupts the interaction between MYC and MAX. It binds to intracellular c-MYC, modulating its thermal stability, reducing the transcriptional targets of c-MYC, and exhibiting anticancer activity (TNBC, triple-negative breast cancer).</p>
    Formula:C19H11ClN4O
    Color and Shape:Solid
    Molecular weight:346.77

    Ref: TM-T206537

  • JY-3-094
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    JY-3-094

    CAS:
    <p>JY-3-094 is a selective Myc inhibitor that targets the hydrophobic domain of Myc and inhibits the formation of the Myc-Max heterodimer, with an IC50 of 33 μM, and can be used for cancer research.</p>
    Formula:C13H8N4O5
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:300.23

    Ref: TM-T86777

  • β-catenin-IN-8
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    β-catenin-IN-8

    CAS:
    <p>β-catenin-IN-8 (Compound 25) is an inhibitor of β-catenin. It effectively lowers the levels of both β-catenin and c-Myc proteins and suppresses Wnt target genes (Fgf20 and Sall4). Additionally, β-catenin-IN-8 exhibits anticancer activity against colorectal cancer and possesses metabolic stability.</p>
    Formula:C15H12ClN3O2S
    Color and Shape:Solid
    Molecular weight:333.79

    Ref: TM-T201581