c-Myc
c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.
Found 76 products of "c-Myc"
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Eragidomide
CAS:Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.Formula:C22H18ClF2N3O4Purity:97.51% - 99.63%Color and Shape:SolidMolecular weight:461.85Ref: TM-T10765
1mg38.00€5mg82.00€10mg133.00€25mg269.00€50mg442.00€100mg595.00€200mg802.00€1mL*10mM (DMSO)84.00€Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurity:99.52%Color and Shape:SolidMolecular weight:333.43MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.82%Color and Shape:SolidMolecular weight:561.3FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formula:C15H13ClFNPurity:98.3% - 99.17%Color and Shape:SolidMolecular weight:261.72Ref: TM-T11285
1mg59.00€2mg85.00€5mg116.00€10mg187.00€25mg331.00€50mg512.00€100mg740.00€500mg1,415.00€MYCi361
CAS:MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).Formula:C26H16ClF9N2O2Purity:99.52%Color and Shape:SolidMolecular weight:594.86MYCMI-6
CAS:MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.Formula:C20H19N7OPurity:99.23%Color and Shape:SolidMolecular weight:373.41Ref: TM-T12134
1mg71.00€5mg152.00€10mg222.00€25mg358.00€50mg512.00€100mg707.00€200mg973.00€500mg1,431.00€Ceramides Mixture
CAS:Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.Formula:C36H71NO4Purity:98%Color and Shape:SolidMolecular weight:581.967KJ Pyr 9
CAS:KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formula:C22H15N3O4Purity:99.56% - ≥98%Color and Shape:SolidMolecular weight:385.37Ref: TM-T15665
2mg37.00€5mg54.00€10mg77.00€25mg138.00€50mg264.00€100mg482.00€200mg647.00€500mg1,009.00€1mL*10mM (DMSO)59.00€FIDAS-3
CAS:FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activitiesFormula:C16H15F2NPurity:97.75%Color and Shape:SolidMolecular weight:259.29Ref: TM-T11284
5mg49.00€10mg73.00€25mg127.00€50mg182.00€100mg264.00€200mg354.00€1mL*10mM (DMSO)48.00€APTO-253
CAS:APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.Formula:C22H14FN5Purity:98.73%Color and Shape:SolidMolecular weight:367.38Ref: TM-T10352
1mg40.00€2mg52.00€5mg75.00€10mg96.00€25mg170.00€50mg255.00€100mg371.00€1mL*10mM (DMSO)84.00€WBC100
CAS:WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathwayFormula:C25H33NO7Purity:98%Color and Shape:SolidMolecular weight:459.53MDEG-541
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].Formula:C35H38N4O7SPurity:98%Color and Shape:SolidMolecular weight:658.76PROTAC MTP3 degrade-1
PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.Formula:C44H38N6O8Color and Shape:SolidMolecular weight:778.27511Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Color and Shape:Odour Solidc-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in ratFormula:C20H22N6OPurity:98%Color and Shape:SolidMolecular weight:362.43c-Myc inhibitor 12
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].Formula:C22H24N6OPurity:98%Color and Shape:SolidMolecular weight:388.47Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.Formula:C13H20N2O6Color and Shape:SolidMolecular weight:300.308c-Myc inhibitor 7
CAS:c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.Formula:C35H30N6O5Color and Shape:SoildMolecular weight:614.65MYC-IN-2
CAS:MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.Formula:C25H17N3O2SColor and Shape:SolidMolecular weight:423.49RA-V
RA-V is a natural product that can be used as a reference standard.Formula:C160H202N24O41Color and Shape:SolidMolecular weight:3117.5c-Myc inhibitor 5
DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.Formula:C30H46N12Color and Shape:SolidMolecular weight:574.77c-Myc inhibitor 10
CAS:c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.Formula:C28H38N6O3Color and Shape:SolidMolecular weight:506.64Anticancer agent 84
CAS:Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.Formula:C57H67N7O9Color and Shape:SolidMolecular weight:994.18VGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.Formula:C121H218N46O32Molecular weight:2827.68453c-Myc inhibitor 13
c-Myc inhibitor13 (compound A6) is an inhibitor of c-MYC transcription. It selectively stabilizes c-MYCG4 and inhibits G4-related c-MYC transcription.Formula:C30H39N9OMolecular weight:541.32776CSI86
CSI86 is a PROTAC degrader targeting MYC, exhibiting antiproliferative activity (IC50: 13-18 μM).Formula:C48H50F9N7O7SColor and Shape:SolidMolecular weight:1040Cotylenin A
CAS:Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.Formula:C33H50O11Color and Shape:SolidMolecular weight:622.744H122
H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)Formula:C45H45ClFN5O8Color and Shape:SolidMolecular weight:838.319VPC-70063
CAS:VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.Formula:C16H12F6N2SPurity:99.98%Color and Shape:SolidMolecular weight:378.34Ref: TM-T60019
1mg49.00€5mg101.00€10mg152.00€25mg268.00€50mg385.00€100mg560.00€200mg790.00€1mL*10mM (DMSO)130.00€VTX-0811
VTX-0811 is a human IgG4 monoclonal antibody (mAb) that targets PSGL1/CD162. It modulates immune signaling pathways by enhancing TNF-α/NF-κB and chemokine-mediated signaling while reducing oxidative phosphorylation, fatty acid metabolism, and Myc signaling. VTX-0811 increases the proportion of CD8+ T cells among infiltrating T cells and exhibits antitumor activity in humanized mouse PDX models of melanoma.Color and Shape:Odour LiquidKL4-219A
KL4-219A is a selective covalent degrader of the MYC, inhibiting MYC transcriptional activity and degrading MYC in a proteasome-dependent manner .Formula:C20H22N2O3SPurity:99.68%Color and Shape:SolidMolecular weight:370.47PROTAC LZK-IN-1
CAS:PROTAC LZK-IN-1 (Compound 21A) is a PROTAC molecule that targets the degradation of LZK (leucine zipper kinase, encoded by MAP3K13). At a concentration of 10 μM, PROTAC LZK-IN-1 facilitates the degradation of LZK and inhibits the expression of p53 and c-MYC, leading to reduced viability of global head and neck squamous cell carcinoma (HNSCC) cell lines. This compound is applicable in anticancer research.
Formula:C51H64F2N10O5SColor and Shape:SolidMolecular weight:967.18c-Myc ligand 1
CAS:c-Mycligand 1 is a c-Myc inhibitor and functions as a ligand for target proteins in PROTAC (Proteolysis Targeting Chimeras). It is utilized in the synthesis of PROTAC c-Myc inhibitor 7.Formula:C13H10N2O2Molecular weight:226.23sAJM589
CAS:sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.Formula:C16H10N2OPurity:98%Color and Shape:SolidMolecular weight:246.26IRES-C11
CAS:IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Formula:C13H11Cl2NO4Purity:99.89%Color and Shape:SolidMolecular weight:316.14Ref: TM-T40419
1mg94.00€5mg222.00€10mg356.00€25mg708.00€50mg1,063.00€100mg1,674.00€200mg2,242.00€1mL*10mM (DMSO)245.00€(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:364.35Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:SolidMolecular weight:682.75Saxagliptin
CAS:Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.Formula:C18H25N3O2Purity:99.17% - 99.95%Color and Shape:SolidMolecular weight:315.41Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purity:99.51% - 99.61%Color and Shape:SolidMolecular weight:526.88Ref: TM-T4367
1mg50.00€5mg94.00€10mg165.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)110.00€10074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purity:99.51% - 99.94%Color and Shape:SolidMolecular weight:332.31Ref: TM-T3686
2mg39.00€5mg59.00€10mg84.00€25mg135.00€50mg213.00€100mg375.00€200mg535.00€500mg853.00€1mL*10mM (DMSO)65.00€ML327
CAS:ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formula:C19H18N4O4Purity:98.47%Color and Shape:SolidMolecular weight:366.37Ref: TM-T4252
1mg47.00€2mg62.00€5mg92.00€10mg137.00€25mg222.00€50mg356.00€100mg612.00€200mg850.00€1mL*10mM (DMSO)101.00€Lusianthridin
CAS:Lusianthridin is a natural product from Dendrobium venustum.Formula:C15H14O3Purity:98.49%Color and Shape:SolidMolecular weight:242.27NNK
CAS:NNK is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.Cost-effective and quality-assured.Formula:C10H13N3O2Purity:99.63% - 99.92%Color and Shape:SolidMolecular weight:207.23Ref: TM-T20533
5mg57.00€10mg90.00€25mg150.00€50mg215.00€100mg260.00€200mg385.00€500mg617.00€1mL*10mM (DMSO)62.00€10058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purity:98% - 99.87%Color and Shape:SolidMolecular weight:249.35APTO-253 HCl
CAS:APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.Formula:C22H15ClFN5Color and Shape:SolidMolecular weight:403.8410074-A4
CAS:10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features fromFormula:C18H14Cl2N2O3SPurity:99.06%Color and Shape:SolidMolecular weight:409.29Ref: TM-T9628
1mg56.00€2mg80.00€5mg114.00€10mg177.00€25mg318.00€50mg454.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)101.00€Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Formula:C15H20O5Purity:99.58%Color and Shape:SolidMolecular weight:280.32Ref: TM-T21065
1mg95.00€5mg187.00€10mg329.00€25mg560.00€50mg800.00€100mg1,103.00€1mL*10mM (DMSO)281.00€NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purity:99.16% - 99.27%Color and Shape:SolidMolecular weight:637.76BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formula:C12H9BrN2OSPurity:≥95%Color and Shape:SolidMolecular weight:309.18Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:98.91% - 99.96%Color and Shape:SolidMolecular weight:533.95
