CymitQuimica logo
ROCK

ROCK

ROCK (Rho-associated protein kinase) inhibitors target ROCK kinases, which are involved in the regulation of the cytoskeleton, cell shape, and motility. ROCK plays a significant role in the control of cell division, particularly in processes such as cytokinesis. Inhibiting ROCK can lead to changes in cell cycle dynamics, cell motility, and apoptosis, making these inhibitors valuable in cancer research, neurobiology, and cardiovascular studies. At CymitQuimica, we provide a selection of high-quality ROCK inhibitors to support your research in cell biology, cytoskeletal dynamics, and disease mechanisms.

Found 66 products for "ROCK".

products per page.
  • Y-33075 dihydrochloride
    Targetmol
    + Info

    Y-33075 dihydrochloride

    CAS:
    Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).
    Formula:C16H18Cl2N4O
    Purity:98.88% - 99.89%
    Color and Shape:Solid
    Molecular weight:353.246

    Ref: TM-T13384L

  • ROCK inhibitor-2
    Targetmol
    + Info

    ROCK inhibitor-2

    CAS:
    ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
    Formula:C21H20N2O2
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:332.3957

    Ref: TM-T12746

  • Netarsudil Dihydrochloride
    Targetmol
    + Info

    Netarsudil Dihydrochloride

    CAS:
    Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter (NET) and is effective in reducing intraocular pressure (IOP).Cost-effective and quality-assured.
    Formula:C28H29Cl2N3O3
    Purity:99.92% - 99.98%
    Color and Shape:White Solid
    Molecular weight:526.454

    Ref: TM-T10358

  • CMPD101
    Targetmol
    + Info

    CMPD101

    CAS:
    CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).
    Formula:C24H21F3N6O
    Purity:99.01% - 99.52%
    Color and Shape:Solid
    Molecular weight:466.46

    Ref: TM-T14989

  • CymitQuimica logo
    Targetmol
    + Info

    ROCK2-IN-9

    ROCK2-IN-9 (compound 7u), a selective ROCK2 inhibitor with an IC50 value of 36.8 nM, demonstrates anticancer properties by impeding cancer cell migration and invasion. This action is achieved through the regulation of various actin cytoskeleton cellular activities. It holds potential for use in breast cancer research.
    Formula:C28H30N8O2
    Color and Shape:Solid
    Molecular weight:510.59

    Ref: TM-T200128

  • WAY-656935
    Targetmol
    + Info

    WAY-656935

    CAS:
    WAY-656935 inhibits ROCK.
    Formula:C20H28ClN3O3S
    Purity:97%
    Color and Shape:Solid
    Molecular weight:425.973

    Ref: TM-T77609

  • Y-39983 hydrochloride
    Targetmol
    + Info

    Y-39983 hydrochloride

    CAS:
    Y-39983 hydrochloride (SNJ-1656) is a selective Rho-associated coiled coil-forming protein kinase (ROCK) inhibitor.
    Formula:C16H17ClN4O
    Molecular weight:316.79

    Ref: TM-T9431

  • Ripasudil free base
    Targetmol
    + Info

    Ripasudil free base

    CAS:
    Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.
    Formula:C15H18FN3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:323.386

    Ref: TM-T7492

  • Fasudil
    Targetmol
    + Info

    Fasudil

    CAS:
    Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
    Formula:C14H17N3O2S
    Purity:99.84% - 99.97%
    Color and Shape:White Solid
    Molecular weight:291.369

    Ref: TM-T1606

  • CymitQuimica logo
    Targetmol
    + Info

    ROCK2-IN-11

    ROCK2-IN-11 (Compound A20) is a selective ROCK2 inhibitor with an IC50 of 0.18 μM against ROCK2, demonstrating greater potency over ROCK1. It is applicable in the research of idiopathic pulmonary fibrosis and chronic graft-versus-host disease (cGVHD).

    Ref: TM-T212975

  • S6(229-239), Amide, biotinalyted
    Targetmol
    + Info

    S6(229-239), Amide, biotinalyted

    S6(229-239), Amide, biotinylated, is a bioactive peptide known as a substrate for Rho-kinase II.
    Formula:C64H119N27O15S
    Molecular weight:1537.90997

    Ref: TM-TP3440

  • GKI-1 HCl
    Targetmol
    + Info

    GKI-1 HCl

    GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
    Formula:C15H13Cl2N3
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:306.19

    Ref: TM-T11402L

  • Verosudil
    Targetmol
    + Info

    Verosudil

    CAS:
    Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing aqueous outflow.
    Formula:C17H17N3O2S
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:327.401

    Ref: TM-T60924

  • GSK269962A hydrochloride
    Targetmol
    + Info

    GSK269962A hydrochloride

    CAS:
    GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and inhibits ROCK1 and ROCK2.
    Formula:C29H31ClN8O5
    Color and Shape:Solid
    Molecular weight:607.06

    Ref: TM-T39519

  • Cotosudil
    Targetmol
    + Info

    Cotosudil

    CAS:
    Cotosudil is a ROCK kinase inhibitor with antihypertensive activity used to treat or prevent neurodegenerative diseases.
    Formula:C16H21N3O2S
    Purity:98.41%
    Color and Shape:Solid
    Molecular weight:319.422

    Ref: TM-T38654

  • Belumosudil mesylate
    Targetmol
    + Info

    Belumosudil mesylate

    CAS:
    Belumosudil mesylate (KD025 mesylate) is a ROCK2 inhibitor with antifibrotic activity, and can be used in chronic graft-versus-host disease research.
    Formula:C27H28N6O5S
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:548.61

    Ref: TM-T39555

  • SAR407899
    Targetmol
    + Info

    SAR407899

    CAS:
    SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
    Formula:C14H16N2O2
    Purity:99.42%
    Color and Shape:White Solid
    Molecular weight:244.289

    Ref: TM-T7391

  • RKI1313
    Targetmol
    + Info

    RKI1313

    CAS:
    RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion
    Formula:C17H16N4O2S
    Purity:99.70% - ≥95%
    Color and Shape:White Solid
    Molecular weight:340.4

    Ref: TM-T2011

  • ROCK-IN-2
    Targetmol
    + Info

    ROCK-IN-2

    CAS:
    ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.
    Formula:C18H13ClF2N6O
    Purity:97.29%
    Color and Shape:Solid
    Molecular weight:402.79

    Ref: TM-TQ0110

  • SAR407899 hydrochloride
    Targetmol
    + Info

    SAR407899 hydrochloride

    CAS:
    SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and
    Formula:C14H17ClN2O2
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:280.75

    Ref: TM-T23308