HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
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TRAP1-IN-1
TRAP1-IN-1 (compound 35) is a potent, selective TRAP1 inhibitor affecting the mitochondrial variant of Hsp90.
Formula:
C45H39F7N2O4P2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
866.74
Ref: TM-T79285
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Zelavespib hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 …
Purity:
98%
Ref: TM-T80742
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
AT-533
CAS:908112-37-8
AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and …
Formula:
C23H30N4O3
Purity:
99.54%
Color and Shape:
Soild
Molecular weight:
410.51
Ref: TM-T67836
| 1mg | 51.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 656.00 € | ||
| 200mg | 882.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NDNA3
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane …
Formula:
C28H32N2O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
476.63
Ref: TM-T78809
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NPX800
CAS:1693734-80-3
NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in …
Formula:
C32H32FN5O4
Purity:
99.26%
Color and Shape:
Liquid
Molecular weight:
569.63
Ref: TM-T9804
| 1mg | 94.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 612.00 € | ||
| 50mg | 878.00 € | ||
| 100mg | 1,193.00 € | ||
| 1mL*10mM (DMSO) | 299.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent …
Formula:
C31H35F3N2O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.68
Ref: TM-T78808
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Calyxin H
CAS:202596-22-3
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it …
Formula:
C35H34O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
566.64
Ref: TM-TN3572
| 1mg | 236.00 € | ||
| 1mL*10mM (DMSO) | 840.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
TRAP1-IN-2
CAS:3031102-92-5
TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein …
Formula:
C46H42F6N2O5P2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
878.77
Ref: TM-T79286
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
HSP90-IN-23
HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an …
Formula:
C22H24N2O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
444.5
Ref: TM-T78942
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Debio 0932
CAS:1061318-81-7
Debio 0932 is an orally active inhibitor of HSP90 (IC50s: 100 and 103 nM for …
Formula:
C22H30N6O2S
Color and Shape:
Solid
Molecular weight:
442.58
Ref: TM-T15088
| 2mg | 70.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
PU-H71
CAS:873436-91-0
PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.
Formula:
C18H21IN6O2S
Purity:
98.31%
Color and Shape:
Solid
Molecular weight:
512.37
Ref: TM-T6960
| 1mg | 39.00 € | ||
| 5mg | 64.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 336.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Alvespimycin
CAS:467214-20-6
Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding …
Formula:
C32H48N4O8
Purity:
100%
Color and Shape:
Solid
Molecular weight:
616.75
Ref: TM-T20890
| 5mg | 95.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 396.00 € | ||
| 100mg | 576.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Grp94 Inhibitor-1
CAS:2234897-35-7
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
Formula:
C22H28N2O2
Purity:
97.02%
Color and Shape:
Solid
Molecular weight:
352.47
Ref: TM-T7261
| 5mg | 48.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 189.00 € | ||
| 100mg | 328.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Calenduloside E
CAS:26020-14-4
Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the …
Formula:
C36H56O9
Purity:
96.16%
Color and Shape:
Solid
Molecular weight:
632.82
Ref: TM-TJS0928
| 1mg | 133.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 463.00 € | ||
| 25mg | 755.00 € | ||
| 50mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 348.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Paeoniflorin
CAS:23180-57-6
Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.
Formula:
C23H28O11
Purity:
96.9% - 97.16%
Color and Shape:
White Fine Powder
Molecular weight:
480.46
Ref: TM-T2230
| 25mg | 53.00 € | ||
| 50mg | 62.00 € | ||
| 100mg | 93.00 € | ||
| 500mg | 235.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Gedunin
CAS:2753-30-2
Gedunin, a Meliaceae seed limonoid, inhibits Hsp90 and ovarian cancer growth.
Formula:
C28H34O7
Purity:
99.38% - 99.68%
Color and Shape:
Solid
Molecular weight:
482.57
Ref: TM-T21883
| 1mg | 392.00 € | ||
| 5mg | 1,167.00 € | ||
| 10mg | 1,594.00 € | ||
| 25mg | 2,362.00 € | ||
| 50mg | 3,187.00 € | ||
| 100mg | 4,297.00 € | ||
| 1mL*10mM (DMSO) | 1,281.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Ganetespib
CAS:888216-25-9
Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential …
Formula:
C20H20N4O3
Purity:
97.29% - 99.95%
Color and Shape:
Solid
Molecular weight:
364.4
Ref: TM-T2309
| 5mg | 66.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 246.00 € | ||
| 200mg | 414.00 € | ||
| 500mg | 686.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
TRC051384
CAS:867164-40-7
TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a …
Formula:
C25H31N5O4
Purity:
92.66%
Color and Shape:
Solid
Molecular weight:
465.54
Ref: TM-T3527
| 1mg | 36.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 206.00 € | ||
| 50mg | 291.00 € | ||
| 100mg | 422.00 € | ||
| 200mg | 608.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
VER49009
CAS:940289-57-6
VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).
Formula:
C19H18ClN3O4
Purity:
100% - 99.17%
Color and Shape:
Solid
Molecular weight:
387.82
Ref: TM-T2268
| 1mg | 59.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 633.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Pimitespib
CAS:1260533-36-5
Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 …
Formula:
C25H26N8O
Purity:
99.22% - 99.49%
Color and Shape:
Solid
Molecular weight:
454.53
Ref: TM-T16994
| 1mg | 39.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 353.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
