HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
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Zelavespib hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 …
Purity:
98%
Color and Shape:
Odour Solid
Ref: TM-T80742
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
2-Methoxyhydroquinone
CAS:824-46-4
2-Methoxyhydroquinone is a phenolic compound that reduces the production of TNF-α-induced chemokine (C-C motif) ligand …
Formula:
C7H8O3
Molecular weight:
140.14
Ref: TM-T203475
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and …
Formula:
C43H50N6O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
762.89
Ref: TM-T79323
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
3-Phenyltoxoflavin
CAS:32502-63-9
3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.
Formula:
C13H11N5O2
Purity:
98.84%
Color and Shape:
Liquid
Molecular weight:
269.26
Ref: TM-T36123
| 1mg | 57.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 753.00 € | ||
| 200mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
HSP90-IN-25
HSP90-IN-25 (compound 4a) is an inhibitor targeting HSP90, specifically impeding its ATPase function [1].
Formula:
C29H48O10
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
556.69
Ref: TM-T78863
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
NPX800
CAS:1693734-80-3
NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in …
Formula:
C32H32FN5O4
Purity:
99.26%
Color and Shape:
Liquid
Molecular weight:
569.63
Ref: TM-T9804
| 1mg | 96.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 375.00 € | ||
| 25mg | 627.00 € | ||
| 50mg | 893.00 € | ||
| 100mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 300.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
H2-Gamendazole
CAS:877768-84-8
H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.
Formula:
C18H13Cl2F3N2O2
Purity:
97.36%
Color and Shape:
Liquid
Molecular weight:
417.21
Ref: TM-T72076
| 1mg | 78.00 € | ||
| 5mg | 190.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 505.00 € | ||
| 50mg | 677.00 € | ||
| 100mg | 929.00 € | ||
| 200mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 215.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Chetomin
CAS:1403-36-7
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding …
Formula:
C31H30N6O6S4
Purity:
98%
Color and Shape:
Off-White To Fawn Solid
Molecular weight:
710.87
Ref: TM-T6804
| 1mg | 97.00 € | ||
| 2mg | 172.00 € | ||
| 5mg | 300.00 € | ||
| 10mg | 480.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
TRAP1-IN-2
CAS:3031102-92-5
TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein …
Formula:
C46H42F6N2O5P2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
878.77
Ref: TM-T79286
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
Calyxin H
CAS:202596-22-3
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it …
Formula:
C35H34O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
566.64
Ref: TM-TN3572
| 1mg | 238.00 € | ||
| 1mL*10mM (DMSO) | 845.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
HSP90-IN-35
CAS:1207597-54-3
HSP90-IN-35 is an inhibitor targeting Hsp90, exhibiting anticancer activity. It demonstrates an IC50 ranging from …
Formula:
C27H33N5O5
Color and Shape:
Liquid
Molecular weight:
507.58
Ref: TM-T201430
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
NDNA3
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane …
Formula:
C28H32N2O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
476.63
Ref: TM-T78809
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
AT-533
CAS:908112-37-8
AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and …
Formula:
C23H30N4O3
Purity:
99.54%
Color and Shape:
Soild
Molecular weight:
410.51
Ref: TM-T67836
| 1mg | 51.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 672.00 € | ||
| 200mg | 905.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent …
Formula:
C31H35F3N2O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.68
Ref: TM-T78808
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
Debio 0932
CAS:1061318-81-7
Debio 0932 is an orally active inhibitor of HSP90 (IC50s: 100 and 103 nM for …
Formula:
C22H30N6O2S
Color and Shape:
Solid
Molecular weight:
442.58
Ref: TM-T15088
| 2mg | 70.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Alvespimycin
CAS:467214-20-6
Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding …
Formula:
C32H48N4O8
Purity:
100%
Color and Shape:
Solid
Molecular weight:
616.75
Ref: TM-T20890
| 5mg | 87.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 592.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
PU-H71
CAS:873436-91-0
PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.
Formula:
C18H21IN6O2S
Purity:
98.31%
Color and Shape:
Solid
Molecular weight:
512.37
Ref: TM-T6960
| 1mg | 39.00 € | ||
| 5mg | 65.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 336.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
TRC051384
CAS:867164-40-7
TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a …
Formula:
C25H31N5O4
Purity:
92.66%
Color and Shape:
Solid
Molecular weight:
465.54
Ref: TM-T3527
| 1mg | 37.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 432.00 € | ||
| 200mg | 622.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Friday 2 May 2025
KRIBB11
CAS:342639-96-7
KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.
Formula:
C13H12N6O2
Purity:
97.25% - 99.91%
Color and Shape:
Solid
Molecular weight:
284.27
Ref: TM-T3652
| 5mg | 51.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 263.00 € | ||
| 100mg | 510.00 € | ||
| 200mg | 717.00 € | ||
| 500mg | 1,093.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Pimitespib
CAS:1260533-36-5
Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 …
Formula:
C25H26N8O
Purity:
99.22% - 99.49%
Color and Shape:
Solid
Molecular weight:
454.53
Ref: TM-T16994
| 1mg | 39.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Friday 2 May 2025
