
HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 169 products of "HSP"
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MAL3-101
CAS:<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Formula:C54H66N4O10Color and Shape:SolidMolecular weight:931.12HS-27
CAS:<p>HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.</p>Formula:C52H60N6O12SPurity:97.09%Color and Shape:SolidMolecular weight:993.1317-DMAP-GA
CAS:<p>17-DMAP-GA, a Geldanamycin analogue, acts as an HSP90 inhibitor, leading to cell cycle abnormalities.</p>Formula:C33H50N4O8Color and Shape:SolidMolecular weight:630.783Alvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Formula:C34H49F3N4O10Color and Shape:SolidMolecular weight:730.34008CCT245232
CAS:<p>CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.</p>Formula:C27H23N3O4Color and Shape:SolidMolecular weight:453.49PU-H71
CAS:<p>PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.</p>Formula:C18H21IN6O2SPurity:98.31% - 99.937%Color and Shape:SolidMolecular weight:512.37Debio 0932
CAS:<p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>Formula:C22H30N6O2SPurity:98.98%Color and Shape:SolidMolecular weight:442.58Palmitic acid-1-13C
CAS:<p>Palmitic acid-13C, a 16-C saturated fatty acid internal standard for GC/LC-MS, is prevalent in plasma lipids and influences protein acylation and COX-2 levels.</p>Formula:C16H32O2Color and Shape:SolidMolecular weight:257.422L-Alanyl-L-glutamine
CAS:<p>L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.</p>Formula:C8H15N3O4Purity:99.71% - 99.97%Color and Shape:SolidMolecular weight:217.22YUM70
CAS:<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Formula:C21H19ClN2O4Purity:97.25%Color and Shape:SolidMolecular weight:398.84MitoBloCK-10
CAS:<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Formula:C12H8FN3O3SPurity:99.51%Color and Shape:SolidMolecular weight:293.27HSF1A
CAS:<p>HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.</p>Formula:C21H19N3O2S2Purity:98.89%Color and Shape:SolidMolecular weight:409.52Dihydroberberine
CAS:<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37PF04929113
CAS:<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Formula:C25H30F3N5O4Purity:99.04%Color and Shape:SolidMolecular weight:521.53PF-04929113 Mesylate
CAS:<p>PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37</p>Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H31N3O5Purity:98% - 99.25%Color and Shape:SolidMolecular weight:465.54MK2-IN-1 hydrochloride
CAS:<p>MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.</p>Formula:C27H26Cl2N4O2Purity:97.32%Color and Shape:SolidMolecular weight:509.43Onalespib
CAS:<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Formula:C24H31N3O3Purity:98.05% - 99.66%Color and Shape:SolidMolecular weight:409.52XL888
CAS:<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Formula:C29H37N5O3Purity:99.18%Color and Shape:SolidMolecular weight:503.64Azadiradione
CAS:<p>Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica</p>Formula:C28H34O5Purity:99.52%Color and Shape:SolidMolecular weight:450.57

