HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 200 products for "HSP".
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gp96-II
Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound is useful for research into inflammatory diseases.Formula:C200H353N59O53SColor and Shape:SolidMolecular weight:4464.37NPX800
CAS:NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Formula:C32H32FN5O4Purity:99.29%Color and Shape:SolidMolecular weight:569.626Palmitic acid-13C sodium
CAS:13C-labeled Palmitic acid, a common long-chain fatty acid in flora/fauna, induces GRP78/CHOP in mouse cells.Formula:CC15H31NaO2Molecular weight:279.4MPC-0767
CAS:MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.Formula:C26H36BrN7O9S2Color and Shape:SolidMolecular weight:734.64DN401
CAS:DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.Formula:C18H19N3O2Purity:99.37%Color and Shape:SolidMolecular weight:309.3624MAL3-101
CAS:MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).Formula:C54H66N4O10Color and Shape:SolidMolecular weight:931.12Hsp110-STAT3 interaction-IN-2
Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).Formula:C24H18F3N5O3Color and Shape:SolidMolecular weight:481.43Shepherdin (79-87)
CAS:Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.Formula:C41H64N12O12SPurity:98%Color and Shape:SolidMolecular weight:949.09JG-258
CAS:JG-258 is an inactive negative control for Hsp70 inhibitors [1] .Formula:C20H22ClN3OS3Color and Shape:SolidMolecular weight:452.06trans-Dehydrocurvularin
CAS:trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.Formula:C16H18O5Color and Shape:SolidMolecular weight:290.315PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.Formula:C43H50N6O7Purity:98%Color and Shape:SolidMolecular weight:762.89Grp94 Inhibitor-2
Grp94 Inhibitor-2 (compound 23) is a cyclopropane analog that exhibits high affinity for Glucose Regulated Protein 94 (Grp94), with dissociation constants (Kd) of 0.48 µM for Grp94 and 0.65 µM for Hsp90α.Formula:C26H25ClFNO4Molecular weight:469.94Cemdomespib
CAS:Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.Formula:C24H30FNO6Color and Shape:SolidMolecular weight:447.5NDNA3
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10AFormula:C28H32N2O3SPurity:98%Color and Shape:SolidMolecular weight:476.63Alvespimycin TFA
Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.Formula:C34H49F3N4O10Color and Shape:SolidMolecular weight:730.34008NMS-E973
CAS:NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.Formula:C22H22N4O7Purity:99.84%Color and Shape:Yellow SolidMolecular weight:454.4327Palmitic acid-13C2
CAS:13C-labeled Palmitic acid is a saturated fatty acid in animals/plants influencing GRP78 and CHOP in mouse cells.Formula:C16H32O2Molecular weight:258.415AlF-NOTA-c-d-VAP
AlF-NOTA-c-d-VAP is a peptide-based PET probe designed for targeting and imaging tumors via GRP78. It exhibits high stability both in vitro and in vivo.Formula:C51H83AlFN17O19SMolecular weight:1315.55713CCT245232
CAS:CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.Formula:C27H23N3O4Color and Shape:SolidMolecular weight:453.4892Debio 0932
CAS:Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.Formula:C22H30N6O2SPurity:98.98%Color and Shape:White SolidMolecular weight:442.578
