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HSP

HSP

HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.

Found 169 products of "HSP"

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  • MAL3-101

    CAS:
    <p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>
    Formula:C54H66N4O10
    Color and Shape:Solid
    Molecular weight:931.12
  • HS-27

    CAS:
    <p>HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.</p>
    Formula:C52H60N6O12S
    Purity:97.09%
    Color and Shape:Solid
    Molecular weight:993.13
  • 17-DMAP-GA

    CAS:
    <p>17-DMAP-GA, a Geldanamycin analogue, acts as an HSP90 inhibitor, leading to cell cycle abnormalities.</p>
    Formula:C33H50N4O8
    Color and Shape:Solid
    Molecular weight:630.783
  • Alvespimycin TFA


    <p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>
    Formula:C34H49F3N4O10
    Color and Shape:Solid
    Molecular weight:730.34008
  • CCT245232

    CAS:
    <p>CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.</p>
    Formula:C27H23N3O4
    Color and Shape:Solid
    Molecular weight:453.49
  • PU-H71

    CAS:
    <p>PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.</p>
    Formula:C18H21IN6O2S
    Purity:98.31% - 99.937%
    Color and Shape:Solid
    Molecular weight:512.37
  • Debio 0932

    CAS:
    <p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>
    Formula:C22H30N6O2S
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:442.58
  • Palmitic acid-1-13C

    CAS:
    <p>Palmitic acid-13C, a 16-C saturated fatty acid internal standard for GC/LC-MS, is prevalent in plasma lipids and influences protein acylation and COX-2 levels.</p>
    Formula:C16H32O2
    Color and Shape:Solid
    Molecular weight:257.422
  • L-Alanyl-L-glutamine

    CAS:
    <p>L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.</p>
    Formula:C8H15N3O4
    Purity:99.71% - 99.97%
    Color and Shape:Solid
    Molecular weight:217.22
  • YUM70

    CAS:
    <p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>
    Formula:C21H19ClN2O4
    Purity:97.25%
    Color and Shape:Solid
    Molecular weight:398.84
  • MitoBloCK-10

    CAS:
    <p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>
    Formula:C12H8FN3O3S
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:293.27
  • HSF1A

    CAS:
    <p>HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.</p>
    Formula:C21H19N3O2S2
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:409.52
  • Dihydroberberine

    CAS:
    <p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>
    Formula:C20H19NO4
    Purity:93.77%
    Color and Shape:Solid
    Molecular weight:337.37
  • PF04929113

    CAS:
    <p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>
    Formula:C25H30F3N5O4
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:521.53
  • PF-04929113 Mesylate

    CAS:
    <p>PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37</p>
    Formula:C26H34F3N5O7S
    Purity:99% - 99.46%
    Color and Shape:Solid
    Molecular weight:617.63
  • Luminespib

    CAS:
    <p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C26H31N3O5
    Purity:98% - 99.25%
    Color and Shape:Solid
    Molecular weight:465.54
  • MK2-IN-1 hydrochloride

    CAS:
    <p>MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.</p>
    Formula:C27H26Cl2N4O2
    Purity:97.32%
    Color and Shape:Solid
    Molecular weight:509.43
  • Onalespib

    CAS:
    <p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>
    Formula:C24H31N3O3
    Purity:98.05% - 99.66%
    Color and Shape:Solid
    Molecular weight:409.52
  • XL888

    CAS:
    <p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>
    Formula:C29H37N5O3
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:503.64
  • Azadiradione

    CAS:
    <p>Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica</p>
    Formula:C28H34O5
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:450.57