
HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 169 products of "HSP"
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CH5164840
CAS:<p>CH5164840: strong HSP90 blocker; excels in NSCLC treatment; boosts erlotinib efficacy on EGFR-mutant tumors.</p>Formula:C19H23N5O2SColor and Shape:SolidMolecular weight:385.48Hsp90-Cdc37-IN-1
CAS:<p>Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.</p>Formula:C43H57FN2O6SPurity:98%Color and Shape:SolidMolecular weight:748.99Vibsanin A
CAS:<p>Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.</p>Formula:C25H38O4Color and Shape:SolidMolecular weight:402.57YM-1
CAS:<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Formula:C20H20ClN3OS2Color and Shape:SolidMolecular weight:417.98BIIB028
CAS:<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Formula:C19H21ClN5O5PColor and Shape:SolidMolecular weight:465.83Retaspimycin
CAS:<p>Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).</p>Formula:C31H45N3O8Purity:98%Color and Shape:SolidMolecular weight:587.7KUNB31
CAS:<p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>Formula:C19H18N2O3Color and Shape:SolidMolecular weight:322.36HSP90-IN-20
CAS:<p>HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.</p>Formula:C26H32N4O4Color and Shape:SolidMolecular weight:464.56Hsp90-IN-17
CAS:<p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>Formula:C21H20N4O7Color and Shape:SolidMolecular weight:440.41Heat Shock Protein Inhibitor II
CAS:<p>Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.</p>Formula:C12H11NO3Color and Shape:SolidMolecular weight:217.22SW02
CAS:<p>SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).</p>Formula:C19H23BrN2O5Color and Shape:SolidMolecular weight:439.3PU24FCl
CAS:<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Formula:C20H21ClFN5O3Color and Shape:SolidMolecular weight:433.86BMS-358233
CAS:<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Formula:C25H25ClN6O2SColor and Shape:SolidMolecular weight:509.02EC 144
CAS:<p>EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.</p>Formula:C21H24ClN5O2Color and Shape:SolidMolecular weight:413.9MPC-3100
CAS:<p>MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].</p>Formula:C22H25BrN6O4SColor and Shape:SolidMolecular weight:549.44Iroxanadine
CAS:<p>Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in</p>Formula:C14H20N4OPurity:98.04% - 99.04%Color and Shape:SolidMolecular weight:260.33AMP-PCP disodium
CAS:<p>AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.</p>Formula:C11H16N5Na2O12P3Purity:99.32%Color and Shape:SolidMolecular weight:549.17SNX0723
CAS:<p>SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.</p>Formula:C22H26FN3O3Purity:99.85%Color and Shape:SolidMolecular weight:399.46Arimoclomol
CAS:<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Formula:C14H20ClN3O3Purity:99.15%Color and Shape:SolidMolecular weight:313.78JG-231
CAS:<p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>Formula:C22H18BrCl2N3OS4Purity:99.79%Color and Shape:SolidMolecular weight:619.47
