HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 179 products of "HSP"
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Vibsanin A
CAS:Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.Formula:C25H38O4Color and Shape:SolidMolecular weight:402.57Displurigen
CAS:Displurigen is an inhibitor of ATPase activity of HSP70.Formula:C15H10O4SPurity:98%Color and Shape:SolidMolecular weight:286.3Icapamespib HCl
CAS:Icapamespib (PU-HZ151) is an HSP90 inhibitor; EC50 of 5 nM, logD of 2.37; targets epichaperomes, effective in cells, mice, and humans.Formula:C19H25Cl2IN6O2SColor and Shape:SolidMolecular weight:599.31CH5015765
CAS:CH5015765: potent, selective HSP90 inhibitor with high affinity and antitumor effects in human cancer mouse models.Formula:C16H13ClN4OSColor and Shape:SolidMolecular weight:344.82YM-01 Tosylate
CAS:YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.
Formula:C27H27N3O4S3Color and Shape:SolidMolecular weight:553.72Grp94-IN-2
CAS:Grp94-IN-2 is a inhibitor of Grp94.Formula:C22H23ClN2O5Color and Shape:SolidMolecular weight:430.88Heat Shock Protein Inhibitor II
CAS:Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.Formula:C12H11NO3Color and Shape:SolidMolecular weight:217.22BF844
CAS:BF844 chemical counters USH3-induced hearing loss by transporting mutated CLRN1 to cell membranes, effectively preserving hearing in vivo.Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.85Hsp90-IN-17
CAS:Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.Formula:C21H20N4O7Color and Shape:SolidMolecular weight:440.41YM-1
CAS:YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.Formula:C20H20ClN3OS2Color and Shape:SolidMolecular weight:417.98HSP90-IN-12
CAS:VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55CH5138303
CAS:CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.Formula:C19H18ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:415.9HSP90-IN-20
CAS:HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.Formula:C26H32N4O4Color and Shape:SolidMolecular weight:464.56Hsp90-IN-15
CAS:Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.Formula:C23H27F3N4Color and Shape:SolidMolecular weight:416.48KUNB31
CAS:KUNB31 is a potent and selective inhibitor of Hsp90β.Formula:C19H18N2O3Color and Shape:SolidMolecular weight:322.36STA-2842
CAS:STA-2842 is an inhibitor of heat shock protein 90 (HSP90).Formula:C29H38N6O5Color and Shape:SolidMolecular weight:550.65Bimoclomol
CAS:Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.Formula:C14H20ClN3O2Color and Shape:SolidMolecular weight:297.78Retaspimycin
CAS:Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).Formula:C31H45N3O8Purity:98%Color and Shape:SolidMolecular weight:587.7BIIB028
CAS:BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.Formula:C19H21ClN5O5PColor and Shape:SolidMolecular weight:465.83MPC-3100
CAS:MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].Formula:C22H25BrN6O4SColor and Shape:SolidMolecular weight:549.44
