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HSP

HSP

HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.

Found 196 products for "HSP".

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  • Hsp90-IN-15
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    Hsp90-IN-15

    CAS:
    Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.
    Formula:C23H27F3N4
    Color and Shape:Solid
    Molecular weight:416.48

    Ref: TM-T62163

  • Retaspimycin
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    Retaspimycin

    CAS:
    Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).
    Formula:C31H45N3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.7

    Ref: TM-T12726

  • KUNB31
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    KUNB31

    CAS:
    KUNB31 is a potent and selective inhibitor of Hsp90β.
    Formula:C19H18N2O3
    Color and Shape:Solid
    Molecular weight:322.36

    Ref: TM-T69779

  • HSP90-IN-20
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    HSP90-IN-20

    CAS:
    HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.
    Formula:C26H32N4O4
    Color and Shape:Solid
    Molecular weight:464.56

    Ref: TM-T73011

  • BIIB028
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    BIIB028

    CAS:
    BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.
    Formula:C19H21ClN5O5P
    Color and Shape:Solid
    Molecular weight:465.83

    Ref: TM-T68383

  • Hsp90-IN-17
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    Hsp90-IN-17

    CAS:
    Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.
    Formula:C21H20N4O7
    Color and Shape:Solid
    Molecular weight:440.41

    Ref: TM-T72996

  • Heat Shock Protein Inhibitor II
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    Heat Shock Protein Inhibitor II

    CAS:
    Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.
    Formula:C12H11NO3
    Color and Shape:Solid
    Molecular weight:217.22

    Ref: TM-T36865

  • YM-1
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    YM-1

    CAS:
    YM-1 is an HSP70 inhibitor; promotes client protein degradation; disrupts protein folding; cancer research tool.
    Formula:C20H20ClN3OS2
    Purity:99.58%
    Color and Shape:Red Solid
    Molecular weight:417.975

    Ref: TM-T73579

  • Vibsanin A
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    Vibsanin A

    CAS:
    Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.
    Formula:C25H38O4
    Color and Shape:Solid
    Molecular weight:402.57

    Ref: TM-T68802

  • PU24FCl
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    PU24FCl

    CAS:
    PU24FCl is a specific inhibitor of tumor Hsp90.
    Formula:C20H21ClFN5O3
    Color and Shape:Solid
    Molecular weight:433.86

    Ref: TM-T28473

  • BMS-358233
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    BMS-358233

    CAS:
    BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.
    Formula:C25H25ClN6O2S
    Color and Shape:Solid
    Molecular weight:509.02

    Ref: TM-T30518

  • Hsp90-Cdc37-IN-1
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    Hsp90-Cdc37-IN-1

    CAS:
    Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.
    Formula:C43H57FN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:748.99

    Ref: TM-T13725

  • CH5164840
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    CH5164840

    CAS:
    CH5164840 is an HSP90 inhibitor; IC50=4.1 nM; oral active; degrades client proteins; cancer research tool.
    Formula:C19H23N5O2S
    Purity:99.50% - 99.80%
    Color and Shape:White Solid
    Molecular weight:385.48

    Ref: TM-T71526

  • Bimoclomol
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    Bimoclomol

    CAS:
    Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.
    Formula:C14H20ClN3O2
    Color and Shape:Solid
    Molecular weight:297.781

    Ref: TM-T13580

  • SNX0723
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    SNX0723

    CAS:
    SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.
    Formula:C22H26FN3O3
    Purity:99.85%
    Color and Shape:White Solid
    Molecular weight:399.4585

    Ref: TM-T28824

  • Iroxanadine
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    Iroxanadine

    CAS:
    Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in
    Formula:C14H20N4O
    Purity:98.04% - 99.04%
    Color and Shape:Solid
    Molecular weight:260.3348

    Ref: TM-T27627

  • Arimoclomol
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    Arimoclomol

    CAS:
    Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (
    Formula:C14H20ClN3O3
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:313.78

    Ref: TM-T13553

  • KU-177
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    KU-177

    CAS:
    KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.
    Formula:C27H23NO8
    Purity:98.1% - 98.54%
    Color and Shape:Solid
    Molecular weight:489.47

    Ref: TM-T63273

  • BX-2819
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    BX-2819

    CAS:
    BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .
    Formula:C21H24N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:428.51

    Ref: TM-T82802

  • HSP90-IN-19
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    HSP90-IN-19

    CAS:
    HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.
    Formula:C29H38O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.61

    Ref: TM-T73038