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HSP

HSP

HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.

Found 169 products of "HSP"

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  • KW-2478

    CAS:
    <p>KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.</p>
    Formula:C30H42N2O9
    Purity:98.68% - 99.52%
    Color and Shape:Solid
    Molecular weight:574.66
  • Alvespimycin

    CAS:
    <p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>
    Formula:C32H48N4O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:616.75
  • Calenduloside E

    CAS:
    <p>Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by</p>
    Formula:C36H56O9
    Purity:96.16% - 98.99%
    Color and Shape:Solid
    Molecular weight:632.82
  • 17-AEP-GA

    CAS:
    <p>17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.</p>
    Formula:C34H50N4O8
    Purity:97.77% - 99.56%
    Color and Shape:Solid
    Molecular weight:642.78
  • Retaspimycin Hydrochloride

    CAS:
    <p>Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).</p>
    Formula:C31H46ClN3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:624.17
  • Bimoclomol

    CAS:
    <p>Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.</p>
    Formula:C14H20ClN3O2
    Color and Shape:Solid
    Molecular weight:297.78
  • CH5138303

    CAS:
    <p>CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.</p>
    Formula:C19H18ClN5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:415.9
  • AMP-PCP

    CAS:
    <p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>
    Formula:C11H18N5O12P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.21
  • JG-48

    CAS:
    <p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>
    Formula:C20H16F3N3OS2
    Color and Shape:Solid
    Molecular weight:435.49
  • Hsp90-IN-15

    CAS:
    <p>Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.</p>
    Formula:C23H27F3N4
    Color and Shape:Solid
    Molecular weight:416.48
  • CCT251236

    CAS:
    <p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>
    Formula:C32H32N4O5
    Purity:98.82% - 99.89%
    Color and Shape:Solid
    Molecular weight:552.62
  • HSP90-IN-12

    CAS:
    <p>VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.</p>
    Formula:C25H36O4
    Color and Shape:Solid
    Molecular weight:400.55
  • YM-01 Tosylate

    CAS:
    <p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>
    Formula:C27H27N3O4S3
    Color and Shape:Solid
    Molecular weight:553.72
  • Displurigen

    CAS:
    <p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>
    Formula:C15H10O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:286.3
  • Malonganenone A

    CAS:
    <p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>
    Formula:C26H38N4O2
    Color and Shape:Solid
    Molecular weight:438.61
  • 6BrCaQ

    CAS:
    <p>6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.</p>
    Formula:C18H15BrN2O3
    Color and Shape:Solid
    Molecular weight:387.23
  • HSP90-IN-22

    CAS:
    <p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>
    Formula:C25H30N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:434.53
  • PU3

    CAS:
    <p>PU3 is an inhibitor of Hsp90.</p>
    Formula:C19H25N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:371.43
  • SEW84

    CAS:
    <p>SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.</p>
    Formula:C19H14F4N4OS
    Color and Shape:Solid
    Molecular weight:422.4
  • HSP90-IN-14

    CAS:
    <p>HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.</p>
    Formula:C14H8Cl2N4O4S
    Color and Shape:Solid
    Molecular weight:399.21