Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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ML324
CAS:ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Formula:C21H23N3O2Purity:98.22% - 98.57%Color and Shape:SolidMolecular weight:349.43Ref: TM-T6593
2mg34.00€5mg49.00€10mg74.00€25mg122.00€50mg205.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)79.00€PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurity:99.31% - 99.91%Color and Shape:SolidMolecular weight:535.98Ref: TM-T4583
1mg38.00€2mg49.00€5mg80.00€10mg111.00€25mg200.00€50mg358.00€100mg523.00€500mg1,108.00€1mL*10mM (DMSO)122.00€C646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formula:C24H19N3O6Purity:98% - 99.21%Color and Shape:SolidMolecular weight:445.42Ref: TM-T2452
2mg46.00€5mg65.00€10mg92.00€25mg185.00€50mg360.00€100mg532.00€500mg1,144.00€1mL*10mM (DMSO)65.00€4-amino-1,8-Naphthalimide
CAS:4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.2WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.22GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purity:99.75%Color and Shape:SolidMolecular weight:612.03Ref: TM-T9826
1mg93.00€5mg182.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)245.00€Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:97.7% - 99.99%Color and Shape:SolidMolecular weight:510.61Ref: TM-T9497
5mg57.00€10mg82.00€25mg111.00€50mg137.00€100mg205.00€200mg309.00€500mg515.00€1mL*10mM (DMSO)66.00€OUL35
CAS:OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Formula:C14H12N2O3Purity:99.2%Color and Shape:SolidMolecular weight:256.26BMS-P5 free base
CAS:BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formula:C27H32N6O2Purity:99.88%Color and Shape:SolidMolecular weight:472.58WIKI4
CAS:WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formula:C29H23N5O3SPurity:99.6% - 99.71%Color and Shape:SolidMolecular weight:521.59Buformin hydrochloride
CAS:Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Formula:C6H16ClN5Purity:97.83%Color and Shape:SolidMolecular weight:193.68Piribedil hydrochloride
CAS:Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.Formula:C16H19ClN4O2Color and Shape:SolidMolecular weight:334.8AK-1
CAS:AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formula:C19H21N3O5SPurity:98.32% - 99.44%Color and Shape:SolidMolecular weight:403.454-(3-Chlorophenyl)-2(3H)-thiazolone
CAS:4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formula:C9H6ClNOSPurity:95.311%Color and Shape:SolidMolecular weight:211.67BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53Ref: TM-T2488
1mg35.00€2mg43.00€5mg63.00€10mg101.00€25mg212.00€50mg351.00€100mg588.00€1mL*10mM (DMSO)73.00€IOX2
CAS:IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formula:C19H16N2O5Purity:98% - 99.59%Color and Shape:SolidMolecular weight:352.34I-CBP112
CAS:I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formula:C27H36N2O5Purity:98.18%Color and Shape:SolidMolecular weight:468.59Ref: TM-T3969
1mg33.00€2mg50.00€5mg92.00€10mg161.00€25mg296.00€50mg425.00€100mg583.00€200mg785.00€1mL*10mM (DMSO)92.00€FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formula:C28H32O6Purity:97% - 97.90%Color and Shape:SolidMolecular weight:464.55Ref: TM-T6838
2mg43.00€5mg63.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)69.00€Eicosapentaenoic Acid sodium
CAS:EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Formula:C20H29NaO2Color and Shape:SolidMolecular weight:324.43Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColor and Shape:SolidMolecular weight:237.21OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formula:C25H27Cl2N5O2Color and Shape:SolidMolecular weight:522.31Perindopril
CAS:Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Formula:C19H32N2O5Color and Shape:White PowderMolecular weight:368.47HNHA
CAS:HNHA is an inhibitor of HDAC.Formula:C17H21NO2SPurity:98.04%Color and Shape:SolidMolecular weight:303.42Ref: TM-T21806
1mg44.00€5mg84.00€10mg135.00€25mg279.00€50mg445.00€100mg640.00€200mg879.00€1mL*10mM (DMSO)90.00€TIQ-A
CAS:TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formula:C11H7NOSPurity:99.75%Color and Shape:SolidMolecular weight:201.24Ref: TM-T50098
1mg52.00€5mg92.00€10mg161.00€25mg290.00€50mg414.00€100mg532.00€200mg737.00€1mL*10mM (DMSO)96.00€4'-Methoxychalcone
CAS:4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formula:C16H14O2Purity:99.86%Color and Shape:SolidMolecular weight:238.285-Ph-IAA
CAS:5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
Formula:C16H13NO2Purity:99.37% - 99.973%Color and Shape:SolidMolecular weight:251.28CPI-455
CAS:CPI-455 is a specific KDM5 inhibitor.Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31Ref: TM-T3552
1mg34.00€2mg49.00€5mg70.00€10mg105.00€25mg178.00€50mg335.00€100mg505.00€1mL*10mM (DMSO)70.00€A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formula:C20H12N2O3SPurity:97.52% - 99.58%Color and Shape:SolidMolecular weight:360.39Ref: TM-T2468
2mg37.00€5mg54.00€10mg74.00€25mg135.00€50mg244.00€100mg440.00€500mg964.00€1mL*10mM (DMSO)56.00€TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:509.67GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formula:C24H28ClN5O2Purity:97.95% - 98.23%Color and Shape:SolidMolecular weight:453.97Ref: TM-T4383
1mg38.00€2mg50.00€5mg84.00€10mg120.00€25mg207.00€50mg344.00€100mg505.00€200mg707.00€1mL*10mM (DMSO)132.00€BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurity:99.87%Color and Shape:SolidMolecular weight:340.36Ref: TM-T9552
1mg84.00€5mg177.00€10mg268.00€25mg537.00€50mg803.00€100mg1,099.00€200mg1,468.00€1mL*10mM (DMSO)195.00€BMS-P5
CAS:BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formula:C27H33ClN6O2Purity:99.88%Color and Shape:SolidMolecular weight:509.04Ref: TM-T22277
2mg44.00€5mg86.00€10mg136.00€25mg268.00€50mg479.00€100mg760.00€200mg1,018.00€1mL*10mM (DMSO)96.00€Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formula:C21H22ClNO4Purity:97.9% - 99.47%Color and Shape:SolidMolecular weight:387.86Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36Ref: TM-T4463
2mg46.00€5mg70.00€10mg109.00€25mg170.00€50mg222.00€100mg344.00€200mg512.00€500mg823.00€1mL*10mM (DMSO)77.00€ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formula:C46H51F3N6O8S2Purity:98.34%Color and Shape:SolidMolecular weight:937.06Ref: TM-T8432
1mg50.00€5mg114.00€10mg177.00€25mg321.00€50mg482.00€100mg677.00€200mg928.00€1mL*10mM (DMSO)185.00€JW 55
CAS:JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formula:C25H26N2O5Purity:99.31% - 99.76%Color and Shape:SolidMolecular weight:434.48GSK591
CAS:GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).Formula:C22H28N4O2Purity:99.35% - 99.45%Color and Shape:SolidMolecular weight:380.48Ref: TM-T6853
1mg46.00€2mg58.00€5mg95.00€10mg137.00€25mg268.00€50mg404.00€100mg567.00€1mL*10mM (DMSO)101.00€CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formula:C19H15N3O2Purity:96.14% - 99.16%Color and Shape:SolidMolecular weight:317.34Ref: TM-T3684
1mg38.00€2mg50.00€5mg84.00€10mg120.00€25mg236.00€50mg356.00€100mg537.00€1mL*10mM (DMSO)77.00€IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Ref: TM-T8719
1mg43.00€5mg87.00€10mg133.00€25mg227.00€50mg344.00€100mg429.00€200mg597.00€1mL*10mM (DMSO)94.00€FM-381
CAS:FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formula:C24H24N6O2Purity:98.44%Color and Shape:SolidMolecular weight:428.49Ref: TM-T5091
1mg47.00€2mg62.00€5mg92.00€10mg128.00€25mg212.00€50mg319.00€100mg485.00€1mL*10mM (DMSO)107.00€Benzamide
CAS:Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.Formula:C7H7NOPurity:99.66%Color and Shape:Colorless Crystals Physical Description White Powder (Ntp 1992)Molecular weight:121.14(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurity:97.57% - 99.97%Color and Shape:SolidMolecular weight:456.99Ref: TM-T2110
1mg34.00€2mg42.00€5mg57.00€10mg74.00€25mg90.00€50mg137.00€100mg178.00€200mg268.00€500mg485.00€1mL*10mM (DMSO)63.00€PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formula:C19H16ClNO3Purity:95.17% - 98.21%Color and Shape:SolidMolecular weight:341.79Ref: TM-T4427
1mg34.00€2mg43.00€5mg63.00€10mg100.00€25mg200.00€50mg334.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)71.00€BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formula:C23H25N9O3SPurity:99.67%Color and Shape:SolidMolecular weight:507.57Ref: TM-T16529
1mg94.00€5mg222.00€10mg334.00€25mg562.00€50mg802.00€100mg1,063.00€200mg1,459.00€1mL*10mM (DMSO)249.00€TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52KG-501
CAS:KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).Formula:C17H13ClNO5PPurity:97.81%Color and Shape:SolidMolecular weight:377.72Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Color and Shape:SolidMolecular weight:356.43Isoxazole
CAS:Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formula:C3H3NOPurity:98% - 99.34%Color and Shape:Colorless LiquidMolecular weight:69.06Tazemetostat hydrobromide
CAS:Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).Formula:C34H45BrN4O4Purity:99.8%Color and Shape:SolidMolecular weight:653.65Ref: TM-T17002
2mg40.00€5mg57.00€10mg77.00€50mg90.00€100mg150.00€200mg219.00€500mg358.00€1mL*10mM (DMSO)79.00€
