Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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MI-503
CAS:<p>MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.</p>Formula:C28H27F3N8SPurity:99.87% - 99.99%Color and Shape:SolidMolecular weight:564.63Tubacin
CAS:<p>Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.</p>Formula:C41H43N3O7SPurity:97.62% - 98.75%Color and Shape:SolidMolecular weight:721.86SETDB1-TTD-IN-1 TFA
<p>SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.</p>Formula:C30H32F3N5O4Color and Shape:SolidMolecular weight:583.6BYK204165
CAS:<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Formula:C15H12N2O2Purity:99.61%Color and Shape:SolidMolecular weight:252.27J-147
CAS:<p>J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.</p>Formula:C18H17F3N2O2Purity:99.61% - >99.99%Color and Shape:SolidMolecular weight:350.33Alobresib
CAS:<p>Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.</p>Formula:C26H23N5O2Purity:97.63%Color and Shape:SolidMolecular weight:437.495-AIQ
CAS:<p>5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.</p>Formula:C9H8N2OPurity:95.95%Color and Shape:SolidMolecular weight:160.17BAZ1A-IN-1
CAS:<p>BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.</p>Formula:C16H12N4O3SPurity:99.87%Color and Shape:SolidMolecular weight:340.36Ruxolitinib (S enantiomer)
CAS:<p>Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.</p>Formula:C17H18N6Purity:99.37% - 99.79%Color and Shape:SolidMolecular weight:306.36ML367
CAS:<p>ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.</p>Formula:C19H12F2N4Purity:99.39%Color and Shape:SolidMolecular weight:334.32I-CBP112
CAS:<p>I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.</p>Formula:C27H36N2O5Purity:98.18%Color and Shape:SolidMolecular weight:468.59CPI-455
CAS:<p>CPI-455 is a specific KDM5 inhibitor.</p>Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31Momelotinib HCl
CAS:<p>Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.</p>Formula:C23H24Cl2N6O2Color and Shape:SolidMolecular weight:487.38BCI-121
CAS:<p>BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.</p>Formula:C14H18BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:340.22SGC2085 HCl
CAS:<p>SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.</p>Formula:C19H24N2O2·HClPurity:99.91%Color and Shape:SolidMolecular weight:348.87Splitomicin
CAS:<p>Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a</p>Formula:C13H10O2Purity:97.09% - 99.11%Color and Shape:SolidMolecular weight:198.224-Phenylbutyric acid
CAS:<p>4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.</p>Formula:C10H12O2Purity:98.40% - 99.76%Color and Shape:SolidMolecular weight:164.2Gandotinib
CAS:<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29Iso-H7 dihydrochloride
CAS:<p>Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.</p>Formula:C14H19Cl2N3O2SPurity:99.53%Color and Shape:White Crystalline SolidMolecular weight:364.29dencichine
CAS:<p>Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.</p>Formula:C5H8N2O5Purity:99.93% - ≥95%Color and Shape:SolidMolecular weight:176.13Cerdulatinib
CAS:<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.543-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formula:C7H6N4Purity:99.16% - >99.99%Color and Shape:SolidMolecular weight:146.15Nudifloramide
CAS:<p>Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).</p>Formula:C7H8N2O2Purity:99.7% - ≥95%Color and Shape:SolidMolecular weight:152.15M1001
CAS:<p>M1001 is a HIF-2α agonist.</p>Formula:C17H17N3O2SPurity:98.83%Color and Shape:SolidMolecular weight:327.4Mivebresib
CAS:<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47GSK467
CAS:<p>GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).</p>Formula:C17H13N5O2Purity:99.55%Color and Shape:SolidMolecular weight:319.32MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46Amifostine trihydrate
CAS:<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Tofacitinib Citrate
CAS:<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formula:C22H28N6O8Purity:99.19% - 99.75%Color and Shape:SolidMolecular weight:504.49DDP-38003 trihydrochloride
<p>DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.</p>Formula:C21H29Cl3N4OPurity:98%Color and Shape:SolidMolecular weight:459.84WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2Selisistat
CAS:<p>Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).</p>Formula:C13H13ClN2OPurity:98.53% - 99.94%Color and Shape:SolidMolecular weight:248.71Fedratinib
CAS:<p>Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.</p>Formula:C27H36N6O3SPurity:97.31% - 99.96%Color and Shape:SolidMolecular weight:524.68BI 2536
CAS:<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Formula:C28H39N7O3Purity:98% - 99.88%Color and Shape:SolidMolecular weight:521.65(+)-JQ-1
CAS:<p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>Formula:C23H25ClN4O2SPurity:97.57% - ≥95%Color and Shape:SolidMolecular weight:456.99Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Formula:C19H20N4O·C7H8O3SPurity:99.34% - 99.87%Color and Shape:SolidMolecular weight:492.59AZD-2461
CAS:<p>AZD2461 is a novel PARP inhibitor.</p>Formula:C22H22FN3O3Purity:98% - 99.87%Color and Shape:SolidMolecular weight:395.43Acetyl Pentapeptide-1 acetate
<p>Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.</p>Formula:C34H55N9O12Purity:99.09%Color and Shape:SolidMolecular weight:781.86Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Formula:C16H12ClN3OPurity:97.79% - 99.24%Color and Shape:SolidMolecular weight:297.74Methyl L-histidinate dihydrochloride
CAS:<p>The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat</p>Formula:C7H13Cl2N3O2Purity:99.74%Color and Shape:White To Off-White PowderMolecular weight:242.1A-196
CAS:<p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>Formula:C18H16Cl2N4Purity:99.92%Color and Shape:SolidMolecular weight:359.25PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formula:C16H17N3O4SPurity:98.74% - 99.19%Color and Shape:SolidMolecular weight:347.39Isoxazole
CAS:<p>Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.</p>Formula:C3H3NOPurity:99.34%Color and Shape:Colorless LiquidMolecular weight:69.06Baricitinib phosphate
CAS:<p>Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.</p>Formula:C16H20N7O6PSPurity:99.4% - 99.82%Color and Shape:SolidMolecular weight:469.41Aurora kinase inhibitor-2
CAS:<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Formula:C23H20N4O3Purity:98.66%Color and Shape:SolidMolecular weight:400.435-Ph-IAA
CAS:<p>5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.</p>Formula:C16H13NO2Purity:99.37% - 99.973%Color and Shape:SolidMolecular weight:251.28WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Formula:C16H14Br2ClN3O3Purity:99.49%Color and Shape:SolidMolecular weight:491.56Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formula:C29H32N4O3SPurity:98.04% - 99.44%Color and Shape:SolidMolecular weight:516.652-hexyl-4-Pentynoic Acid
CAS:<p>2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.</p>Formula:C11H18O2Purity:98%Color and Shape:SolidMolecular weight:182.26
