Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2607 products of "Chromatin/Epigenetics"
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Dbet57
CAS:dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Formula:C34H31ClN8O5SPurity:99.36% - 99.52%Color and Shape:SolidMolecular weight:699.18Ref: TM-T5440
1mg47.00€5mg92.00€10mg147.00€25mg264.00€50mg409.00€100mg592.00€500mg1,224.00€1mL*10mM (DMSO)166.00€MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFormula:C16H15ClFNPurity:99.17%Color and Shape:SolidMolecular weight:275.75Ref: TM-T9262
1mg40.00€5mg90.00€10mg131.00€25mg220.00€50mg314.00€100mg426.00€200mg575.00€1mL*10mM (DMSO)89.00€Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47Ref: TM-T3712
1mg55.00€2mg78.00€5mg92.00€10mg150.00€25mg244.00€50mg437.00€100mg625.00€1mL*10mM (DMSO)94.00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.623-Aminobenzamide
CAS:3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction duringFormula:C7H8N2OPurity:98.4% - 99.5%Color and Shape:White To Off-White PowderMolecular weight:136.15SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Formula:C19H17NO5SPurity:99.1% - 99.51%Color and Shape:SolidMolecular weight:371.41Ref: TM-T3986
1mg34.00€5mg74.00€10mg113.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)82.00€JNJ-64619178
CAS:JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.Formula:C22H23BrN6O2Purity:98.86% - 99.98%Color and Shape:SolidMolecular weight:483.36Ref: TM-T15624
1mg84.00€5mg167.00€10mg260.00€25mg537.00€50mg893.00€100mg1,571.00€1mL*10mM (DMSO)172.00€GeA-69
CAS:GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).Formula:C20H16N2OPurity:99.85%Color and Shape:SolidMolecular weight:300.35TTK21
CAS:TTK21 is an activator of CBP/p300 histone acetyltransferase activity.Formula:C17H15ClF3NO2Purity:98.43%Color and Shape:SolidMolecular weight:357.75Ref: TM-T8778
1mg57.00€5mg105.00€10mg158.00€25mg308.00€50mg462.00€100mg692.00€500mg1,404.00€1mL*10mM (DMSO)114.00€PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12Ref: TM-T6961
1mg39.00€5mg84.00€10mg130.00€25mg193.00€50mg261.00€100mg411.00€200mg605.00€1mL*10mM (DMSO)84.00€LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Ref: TM-T3494
2mg44.00€5mg65.00€10mg94.00€25mg173.00€50mg281.00€100mg424.00€500mg888.00€1mL*10mM (DMSO)65.00€Ref: TM-T5S2358
1mg49.00€2mg69.00€5mg105.00€10mg137.00€25mg197.00€50mg295.00€100mg447.00€1mL*10mM (DMSO)116.00€Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formula:C17H12F3NO4SPurity:99.34% - 99.88%Color and Shape:SolidMolecular weight:383.34Ref: TM-T16679
1mg66.00€5mg144.00€10mg205.00€25mg389.00€50mg625.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)158.00€I-BET151
CAS:I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).Formula:C23H21N5O3Purity:97.34% - 99.63%Color and Shape:SolidMolecular weight:415.44Ref: TM-T2120
1mg48.00€2mg65.00€5mg96.00€10mg115.00€25mg202.00€50mg339.00€100mg507.00€500mg1,130.00€1mL*10mM (DMSO)105.00€Veliparib
CAS:Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formula:C13H16N4OPurity:98.66% - 99%Color and Shape:SolidMolecular weight:244.29Ref: TM-T2591
5mg54.00€10mg77.00€25mg120.00€50mg195.00€100mg314.00€200mg512.00€500mg807.00€1mL*10mM (DMSO)60.00€Tranylcypromine hemisulfate
CAS:Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset ofFormula:C9H11N1H2SO4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:182.23SGI-1027
CAS:SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formula:C27H23N7OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:461.52Ref: TM-T1904
5mg58.00€10mg94.00€25mg163.00€50mg296.00€100mg467.00€500mg1,035.00€1mL*10mM (DMSO)74.00€GSK467
CAS:GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formula:C17H13N5O2Purity:99.55% - 99.85%Color and Shape:SolidMolecular weight:319.32MG 149
CAS:MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46Ref: TM-T6584
1mg50.00€2mg71.00€5mg90.00€10mg167.00€25mg308.00€50mg492.00€100mg708.00€1mL*10mM (DMSO)108.00€UNC3866
CAS:UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formula:C43H66N6O8Purity:88.06% - 99.62%Color and Shape:SolidMolecular weight:795.02GW779439X
CAS:GW779439X is an inhibitor of CDK.Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45Ref: TM-T8866
1mg58.00€2mg82.00€5mg113.00€10mg178.00€25mg404.00€50mg592.00€100mg845.00€1mL*10mM (DMSO)124.00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.37G244-LM
CAS:G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.Formula:C18H22N4O3S2Purity:98.46%Color and Shape:SolidMolecular weight:406.52AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.58Ref: TM-T6380
1mg49.00€5mg92.00€10mg158.00€25mg286.00€50mg442.00€100mg645.00€500mg1,341.00€1mL*10mM (DMSO)100.00€3-Methoxybenzamide
CAS:3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.Formula:C8H9NO2Purity:98.52%Color and Shape:SolidMolecular weight:151.16Amifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurity:99.54%Color and Shape:SolidMolecular weight:505.39Ref: TM-T38624
1mg93.00€2mg117.00€5mg177.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€ARV-771
CAS:ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.Formula:C49H60ClN9O7S2Purity:99.69%Color and Shape:SolidMolecular weight:986.64Ref: TM-T5435
1mg60.00€5mg119.00€10mg187.00€25mg374.00€50mg550.00€100mg772.00€200mg1,026.00€1mL*10mM (DMSO)202.00€Oclacitinib maleate
CAS:Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formula:C15H23N5O2S·C4H4O4Purity:99.17% - 99.92%Color and Shape:SolidMolecular weight:453.51Ref: TM-T6914
1mg37.00€2mg52.00€5mg74.00€10mg94.00€25mg166.00€50mg258.00€100mg432.00€1mL*10mM (DMSO)81.00€CPI-169 racemate
CAS:CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
Formula:C27H36N4O5SPurity:99.59%Color and Shape:SolidMolecular weight:528.66BET bromodomain inhibitor
CAS:BET bromodomain inhibitor is a potent BET inhibitor.Formula:C24H20ClN5O2Purity:98.22% - 99.85%Color and Shape:SolidMolecular weight:445.9Ref: TM-T2072
1mg35.00€2mg50.00€5mg75.00€10mg114.00€25mg187.00€50mg264.00€100mg416.00€1mL*10mM (DMSO)84.00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47(Z)-SMI-4a
CAS:(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.Formula:C11H6F3NO2SPurity:97.66% - 99.93%Color and Shape:SolidMolecular weight:273.23Oclacitinib
CAS:Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000Formula:C15H23N5O2SPurity:98% - 98.45%Color and Shape:White To Off-White SolidMolecular weight:337.44lutidinic acid
CAS:lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.
Formula:C7H5NO4Purity:98.06%Color and Shape:White To Off-White Crystalline PowderMolecular weight:167.12RG108
CAS:RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).Formula:C19H14N2O4Purity:98% - 99.43%Color and Shape:SolidMolecular weight:334.33Ref: TM-T2038
5mg44.00€10mg65.00€25mg111.00€50mg195.00€100mg271.00€200mg380.00€500mg618.00€1mL*10mM (DMSO)52.00€SGC-CBP30
CAS:SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).Formula:C28H33ClN4O3Purity:99.05% - >99.99%Color and Shape:SolidMolecular weight:509.04Ref: TM-T6668
1mg50.00€2mg67.00€5mg84.00€10mg113.00€25mg200.00€50mg334.00€100mg500.00€1mL*10mM (DMSO)94.00€AZD-1480
CAS:AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.Formula:C14H14ClFN8Purity:98.25% - 99.47%Color and Shape:SolidMolecular weight:348.77JAK-IN-5 hydrochloride
CAS:JAK-IN-5 hydrochloride is a JAK inhibitor [1].Formula:C27H32ClFN6OColor and Shape:SolidMolecular weight:511.03Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56ARV-825
CAS:ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formula:C46H47ClN8O9SPurity:97.15% - 98%Color and Shape:SolidMolecular weight:923.43UNC6934
CAS:UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.Formula:C24H21N5O4Purity:98.67%Color and Shape:SolidMolecular weight:443.45Ref: TM-T9584
1mg47.00€5mg92.00€10mg152.00€25mg326.00€50mg485.00€100mg670.00€200mg888.00€1mL*10mM (DMSO)101.00€Annaosanchun
CAS:Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).Formula:C19H32O3Purity:99.58%Color and Shape:SolidMolecular weight:308.46Ruboxistaurin hydrochloride
CAS:Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formula:C28H28N4O3·HClPurity:99.14% - 99.28%Color and Shape:SolidMolecular weight:505.01Ref: TM-T3689
1mg67.00€2mg87.00€5mg148.00€10mg244.00€25mg487.00€50mg702.00€100mg982.00€500mg1,963.00€1mL*10mM (DMSO)190.00€(S)-HH2853
CAS:(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.Formula:C31H36F3N7O3Purity:97.18% - 99.74%Color and Shape:SolidMolecular weight:611.66Chromium(III) acetate
CAS:Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.Formula:C2H3O2CrPurity:99.9%Color and Shape:Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InMolecular weight:76.37CHDI-390576
CAS:CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, and HDAC 9, and can be used in cancer research.Formula:C19H13F4N3O2Purity:98.92% - 99.03%Color and Shape:SolidMolecular weight:391.32MRK-740
CAS:MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.Formula:C25H32N6O3Purity:99.66%Color and Shape:SolidMolecular weight:464.56RGFP966 (E-isomer)
CAS:RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.Formula:C21H19FN4OPurity:99.93%Color and Shape:SolidMolecular weight:362.4TNG-462
CAS:TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).Formula:C28H36N6O2SPurity:98.7%Color and Shape:SolidMolecular weight:520.69Ref: TM-T79873
1mg147.00€5mg255.00€10mg383.00€25mg575.00€50mg863.00€100mg1,305.00€200mg1,755.00€1mL*10mM (DMSO)294.00€
