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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2235 products of "Chromatin/Epigenetics"

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  • CymitQuimica logo
    Targetmol
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    KAT6-IN-2

    <p>KAT6-IN-2 is a potent inhibitor of KAT6, showing promise for use in cancer research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200700

  • Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
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    Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)

    CAS:
    <p>Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491.</p>
    Formula:C88H138N20O34P2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2082.1

    Ref: TM-TP1269

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    Lys-CoA TFA

    <p>Lys-CoA TFA: p300 HAT inhibitor, IC50 50-500 nM, &gt;100x selective vs PCAF, inhibits p300-dependent transcription.</p>
    Formula:C33H54F3N10O21P3S
    Color and Shape:Solid
    Molecular weight:1108.82

    Ref: TM-T73951

  • VPC-70063
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    VPC-70063

    CAS:
    <p>VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.</p>
    Formula:C16H12F6N2S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:378.34

    Ref: TM-T60019

  • Biguanide
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    Biguanide

    CAS:
    <p>Biguanide can reduce oxidative stress in rats with hyperglycemia.</p>
    Formula:C2H7N5
    Color and Shape:Solid
    Molecular weight:101.11

    Ref: TM-T30450

  • BRD3067
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    BRD3067

    CAS:
    <p>BRD3067, a Tubacin derivative, inhibits HDAC6 (IC50 15 nM) and acts as a negative control for Tubacin A, showing anticancer and anti-inflammatory effects.</p>
    Formula:C21H23N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.43

    Ref: TM-T30578

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    CD532 hydrochloride

    <p>CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.</p>
    Color and Shape:Solid

    Ref: TM-T36932

  • Biotinylated-JQ1
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    Biotinylated-JQ1

    CAS:
    <p>Biotin-JQ1 is a bromodomain BRD4 binder; inhibits MM1.S cell growth with EC50 of 0.4μM.</p>
    Formula:C39H53ClN8O6S2
    Color and Shape:Solid
    Molecular weight:829.47

    Ref: TM-T74428

  • CymitQuimica logo
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    pan-BET/BD2-IN-1

    <p>Pan-BET/BD2-IN-1 (compound 6b) is a selective BET protein inhibitor with BRDT-1Ki of 1.05 μM and BRD4-1Ki of 0.68 μM. It effectively inhibits the growth of MM.1S cancer cells with an IC50 value of 2.6 μM.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206487

  • POI ligand 1
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    POI ligand 1

    <p>POI ligand 1 serves as a template for the non-selective HDAC inhibitor Vorinostat. It functions as a target protein ligand (PROTAC target protein ligand) in the creation of PROTAC HDAC degraders with anti-tumor properties. Additionally, POI ligand 1 is utilized in the synthesis of FF2049.</p>
    Formula:C14H21N3O3
    Color and Shape:Solid
    Molecular weight:279.335

    Ref: TM-T204608

  • dBRD9
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    dBRD9

    CAS:
    <p>dBRD9 is a PROTAC.</p>
    Formula:C40H45N7O10
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:783.83

    Ref: TM-T31221

  • BRD4 degrader AT1
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    BRD4 degrader AT1

    CAS:
    <p>BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells.</p>
    Formula:C48H58ClN9O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:972.68

    Ref: TM-T5439

  • Malantide
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    Malantide

    CAS:
    <p>Malantide, a synthetic dodecapeptide, boosts and measures PKA activity by undergoing PKA-induced phosphorylation.</p>
    Formula:C72H124N22O21
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1633.89

    Ref: TM-TP1789

  • CAY10591
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    CAY10591

    CAS:
    <p>SIRT1 activated by CAY10591, mimics caloric restriction, extends lifespan, inhibits apoptosis, suppresses TNF-α, and promotes fat mobilization.</p>
    Formula:C20H25N5O2
    Color and Shape:Solid
    Molecular weight:367.44

    Ref: TM-T35812

  • CymitQuimica logo
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    UNC6864 (Kei)

    <p>UNC6864, an ethylisopropyllysine-containing ligand, exhibits binding affinity to wild-type CBX5, demonstrating a dissociation constant (K D) of 3.3 μM.</p>
    Formula:C42H59N7O11
    Color and Shape:Solid
    Molecular weight:837.96

    Ref: TM-T74223

  • FTX-6058 hydrochloride
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    FTX-6058 hydrochloride

    CAS:
    <p>FTX-6058 hydrochloride is a potent EED inhibitor, induces HbF, and aids sickle cell and β-thalassemia research.</p>
    Formula:C22H19ClFN5O2
    Color and Shape:Solid
    Molecular weight:439.87

    Ref: TM-T40155

  • PROTAC BRD4 Degrader-1
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    PROTAC BRD4 Degrader-1

    CAS:
    <p>PROTAC BRD4 Degrader-1 is an efficacious degrader of BRD4(BRD4 BD1,IC50 of 41.8 nM).</p>
    Formula:C40H37N9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:771.78

    Ref: TM-T13833

  • JAK1/TYK2-IN-1
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    JAK1/TYK2-IN-1

    CAS:
    <p>JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).</p>
    Formula:C18H20F3N7O
    Color and Shape:Solid
    Molecular weight:407.401

    Ref: TM-T39314

  • HDAC-IN-26
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    HDAC-IN-26

    CAS:
    <p>HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC 50 value of 4.7 nM.</p>
    Formula:C24H28FN5O3
    Color and Shape:Solid
    Molecular weight:453.518

    Ref: TM-T39990

  • PROTAC BRM degrader-1
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    PROTAC BRM degrader-1

    CAS:
    <p>PROTAC BRM degrader-1 (compound 17) serves as a PROTAC-based degrader targeting both BRM and BRG1, exhibiting DC50 values of 93 pM and 4.9 nM, respectively [1].</p>
    Formula:C57H69N11O8S
    Color and Shape:Solid
    Molecular weight:1068.29

    Ref: TM-T87261