DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(422 products)
- DNA gyrase(11 products)
- DNA-PK(50 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
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Found 963 products of "DNA Damage/DNA Repair"
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Wistin
CAS:<p>Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .</p>Formula:C23H24O10Color and Shape:SolidMolecular weight:460.43Monascin
CAS:<p>Monascin: azaphilonoid in red-mold rice; anti-tumor and anti-inflammatory.</p>Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43PR-104 sodium
CAS:<p>PR-104 sodium: hypoxia-activated, tumor-targeting pre-prodrug; turns into PR-104A for research.</p>Formula:C14H19BrN4NaO12PSColor and Shape:SolidMolecular weight:601.25Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Formula:C21H22N2O6Color and Shape:SolidMolecular weight:398.409(R)-VX-984
CAS:<p>(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent inhibitor of DNA-PK.</p>Formula:C23H21D2N7OPurity:98%Color and Shape:SolidMolecular weight:415.49BML-278
CAS:<p>BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and</p>Formula:C24H25NO4Purity:99.53%Color and Shape:SolidMolecular weight:391.46Silatecan
CAS:<p>Silatecan is a useful organic compound for research related to life sciences. The catalog number is T67968 and the CAS number is 220913-32-6.</p>Formula:C26H30N2O5SiColor and Shape:SoildMolecular weight:478.61Banoxantrone (D12)
CAS:<p>Banoxantrone D12, deuterium-labeled version, reduces to AQ4 - a stable DNA-targeting topoisomerase II inhibitor.</p>Formula:C22H28N4O6Purity:98%Color and Shape:SolidMolecular weight:456.55PPAR agonist 6
PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].Color and Shape:Odour Solid23-epi-26-Deoxyactein
CAS:<p>23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3].</p>Formula:C37H56O10Color and Shape:SolidMolecular weight:660.83PPARγ/GR modulator 1
<p>PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits</p>Formula:C14H10FNO4Color and Shape:SolidMolecular weight:275.23Macrocalin B
CAS:<p>Macrocalin B is a diterpenoid against tumor cell proliferation and telomerase activity.</p>Formula:C20H26O6Color and Shape:SolidMolecular weight:362.42HDAC-IN-78
<p>HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.</p>Color and Shape:Odour SolidDNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Color and Shape:Odour SolidVH 032 amide-PEG1-acid
CAS:<p>VHL ligand for PROTAC R&D; E3 ligase with PEG1 linker and carboxylic acid for target conjugation.</p>Formula:C28H38N4O7SColor and Shape:SolidMolecular weight:574.69Amrubicin
CAS:<p>The compound is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II.</p>Formula:C25H25NO9Purity:98%Color and Shape:SolidMolecular weight:483.47Murrayanol
<p>Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.</p>Formula:C24H29NO2Color and Shape:SolidMolecular weight:363.501HDAC9-IN-1
<p>HDAC9-IN-1 (Compound 7g) is a potent inhibitor of HDAC9, exhibiting an IC50 of 40 nM. This compound effectively suppresses various human cancer cell lines, induces apoptosis, modulates caspase-related proteins and p38, and results in DNA damage.</p>Formula:C27H22N4O3SColor and Shape:SolidMolecular weight:482.55Antitumor agent-63
CAS:<p>Compound 40, a non-toxic 20(S)-O-CPT glycoconjugate, is stable, with low Topo I inhibition.</p>Formula:C38H46N4O18Color and Shape:SolidMolecular weight:846.79SIRT-IN-5
<p>SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.</p>Color and Shape:Odour Solid
