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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 959 products of "DNA Damage/DNA Repair"

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  • SR 2595
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    SR 2595

    CAS:
    <p>SR2595 is an inverse agonist of nuclear receptor PPARγ with an IC 50 of 30 nM [1].</p>
    Formula:C37H38N2O3
    Color and Shape:Solid
    Molecular weight:558.71

    Ref: TM-T22154

  • BMS-250749
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    BMS-250749

    CAS:
    <p>BMS-250749 is a fluoroglycosylated fluoroindolocarbazole, it has antitumor activity.</p>
    Formula:C26H18F3N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:525.43

    Ref: TM-T26845

  • HDAC6-IN-21
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    HDAC6-IN-21

    CAS:
    <p>HDAC6-IN-21 (compound 13) is an irreversible inhibitor of histone deacetylase 6 (HDAC6) [1].</p>
    Formula:C14H13F2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.28

    Ref: TM-T82226

  • DS-6930
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    DS-6930

    CAS:
    <p>DS-6930 is an potent and selective PPAR γ Agonists with EC50 of 41 nM.</p>
    Formula:C23H21N3O4
    Color and Shape:Solid
    Molecular weight:403.43

    Ref: TM-T61976

  • CM-675
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    CM-675

    CAS:
    <p>CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to</p>
    Formula:C31H32N6O3
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:536.62

    Ref: TM-T10841

  • SIRT6-IN-3
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    SIRT6-IN-3

    CAS:
    <p>SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts</p>
    Formula:C21H30Br3ClN6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.73

    Ref: TM-T79689

  • Makaluvamine A
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    Makaluvamine A

    CAS:
    <p>Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.</p>
    Formula:C11H11N3O
    Color and Shape:Solid
    Molecular weight:201.22

    Ref: TM-T70592

  • Tankyrase-IN-5
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    Tankyrase-IN-5

    CAS:
    <p>Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory</p>
    Formula:C17H18N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:282.34

    Ref: TM-T79026

  • SU-11752
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    SU-11752

    CAS:
    <p>SU-11752 selectively inhibits DNA-PK by competing with ATP, enhances ionizing radiation sensitivity without affecting cell cycle or ATM activity.</p>
    Formula:C26H27N3O5S
    Color and Shape:Solid
    Molecular weight:493.57

    Ref: TM-T68870

  • Pparδ agonist 1
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    Pparδ agonist 1

    CAS:
    <p>Pparδ agonist 1 is an agonist of PPAR-δ(EC50 of 5.06 nM).</p>
    Formula:C26H27NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.5

    Ref: TM-T12528

  • U-46619
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    U-46619

    CAS:
    <p>U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (</p>
    Formula:C21H34O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:350.49

    Ref: TM-T17189

  • ATR-IN-20
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    ATR-IN-20

    <p>ATR-IN-20: potent ATR inhibitor, IC50=3nM; inhibits mTOR, IC50=18nM; selective vs PI3Kα, ATM, DNA-PK; good pharmacokinetics; anticancer.</p>
    Formula:C29H31N5O4S
    Color and Shape:Solid
    Molecular weight:545.65

    Ref: TM-T73301

  • CAY10410
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    CAY10410

    CAS:
    <p>CAY10410 is a PGD2/PGJ2 analog, modified for enhanced PPARγ activity and metabolic stability, non-toxic to SH-SY5Y cells at ≤25μM.</p>
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.45

    Ref: TM-T35811

  • LMP744 hydrochloride
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    LMP744 hydrochloride

    CAS:
    <p>LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. </p>
    Formula:C24H25ClN2O7
    Purity:99.59% - 99.85%
    Color and Shape:Solid
    Molecular weight:488.92

    Ref: TM-T11872L

  • AZ 5704
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    AZ 5704

    CAS:
    <p>ATM kinase inhibitor with 0.6 nM IC50, &gt;600-fold selective, enhances irinotecan effects, oral use.</p>
    Formula:C23H23FN6O2
    Color and Shape:Solid
    Molecular weight:434.47

    Ref: TM-T35942

  • 9A1P9
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    9A1P9

    CAS:
    <p>9A1P9, a multi-tail ionizable cationic phospholipid, facilitates membrane destabilization and is applicable for CRISPR-Cas9 gene editing in mice [1].</p>
    Formula:C27H58NO4P
    Color and Shape:Solid
    Molecular weight:491.73

    Ref: TM-T84640

  • BO 2367
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    BO 2367

    CAS:
    <p>BO 2367, a topoisomerase inhibitor, is used to suppress the growth of tumor .</p>
    Formula:C21H22ClF2N3O3
    Color and Shape:Solid
    Molecular weight:437.87

    Ref: TM-T26883

  • ATR-IN-22
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    ATR-IN-22

    CAS:
    <p>ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells with an IC50 value of less than 1 μM and</p>
    Formula:C25H31N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:445.56

    Ref: TM-T79033

  • ATR-IN-5
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    ATR-IN-5

    CAS:
    <p>ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair.</p>
    Formula:C27H32F3N9O
    Color and Shape:Solid
    Molecular weight:555.6

    Ref: TM-T63923

  • Topoisomerase I inhibitor 9
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    Topoisomerase I inhibitor 9

    CAS:
    <p>Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial activity, demonstrating an IC50 value</p>
    Formula:C23H15Br2FN2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.19

    Ref: TM-T80967