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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 958 products of "DNA Damage/DNA Repair"

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  • Epigenetic factor-IN-1

    CAS:
    <p>Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.</p>
    Formula:C32H34FN5O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:667.77
  • PR-104A

    CAS:
    <p>PR-104A is a hypoxia-targeted anticancer agent.</p>
    Formula:C14H19BrN4O9S
    Color and Shape:Solid
    Molecular weight:499.29
  • ATM-IN-1

    CAS:
    <p>ATM-IN-1 is a potent inhibitor of ATM. ATM-IN-1 has shown research potential in cancer and neurological diseases.</p>
    Formula:C30H36N6O3
    Color and Shape:Solid
    Molecular weight:528.65
  • Pradofloxacin

    CAS:
    <p>Pradofloxacin is a fluoroquinolone antibioticthat exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV.</p>
    Formula:C21H21FN4O3
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:396.41
  • DNMT-IN-3

    CAS:
    <p>DNMT-IN-3 is a DNA Methyltransferase (DNMT) inhibitor with an IC50 of 60 nM against Plasmodium falciparum (Plasmodium), demonstrating antimalarial activity and suitability for malaria-related research [1].</p>
    Formula:C37H39N7O
    Color and Shape:Solid
    Molecular weight:597.75
  • MPI_5a

    CAS:
    <p>MPI_5a selectively inhibits HDAC6 (IC50=36 nM), slightly affects other HDACs, and blocks acyl-tubulin build-up (IC50=210 nM).</p>
    Formula:C16H17N3O3
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:299.32
  • DNA-PK-IN-10

    CAS:
    <p>DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].</p>
    Formula:C25H28N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:444.53
  • 9-Chloromethyl-10-hydroxy-11-F-Camptothecin

    CAS:
    <p>9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential</p>
    Formula:C22H18ClFN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:428.84
  • SRT3657

    CAS:
    <p>SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.</p>
    Formula:C40H54N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:774.97
  • NH2-methylpropanamide-Exatecan TFA

    CAS:
    <p>Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.</p>
    Formula:C30H30F4N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:634.58
  • DY-46-2

    CAS:
    <p>DY-46-2 is a DNMT3A inhibitor (IC50: 0.39 ± 0.23 μM) with anticancer activity and is used in cancer and tumor research.</p>
    Formula:C19H22N6O5S
    Purity:99.12% - 99.12%
    Color and Shape:Solid
    Molecular weight:446.48
  • HDAC/BET-IN-1

    CAS:
    <p>HDAC/BET-IN-1 inhibits HDAC1 (IC50: 0.163 μM), HDAC6 (IC50: 0.067 μM), BRD4 (Ki: 0.076 μM), and fights leukemia.</p>
    Formula:C29H40N4O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:604.71
  • Trovafloxacin mesylate

    CAS:
    <p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>
    Formula:C21H19F3N4O6S
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:512.46
  • NT160

    CAS:
    <p>NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used in the study of neurological diseases.</p>
    Formula:C21H21F3N4O2
    Purity:99.3%
    Color and Shape:Solid
    Molecular weight:418.41
  • Antipsychotic agent 54

    CAS:
    <p>Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM).</p>
    Formula:C21H23FN2O4
    Purity:98.10%
    Color and Shape:Solid
    Molecular weight:386.42
  • HDAC6-IN-8

    CAS:
    <p>Compound 12C, with altered cap groups, shows wide-range enzyme inhibition; 9m and 9q target HDAC6 specifically.</p>
    Formula:C23H17BrFN5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:510.32
  • Bocodepsin

    CAS:
    <p>Bocodepsin (OKI-179) is a selective, orally active inhibitor of histone deacetylases (HDAC) with demonstrated antitumor efficacy.</p>
    Formula:C26H39N5O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:581.75
  • ATR-IN-29

    CAS:
    <p>ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM and demonstrates antiproliferative activity [1].</p>
    Formula:C19H22N8O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.43
  • Zabofloxacin

    CAS:
    <p>Zabofloxacin inhibits bacterial topoisomerases II/IV, effectively targeting gram-positive pathogens like S. aureus and S. pneumoniae.</p>
    Formula:C19H20FN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:401.39
  • 10-Nitrolinoleic acid

    CAS:
    <p>10-Nitrolinoleate, a nitration product of linoleate, modulates PPARγ, enhancing glucose uptake, and aids in muscle relaxation via NO/cGMP pathway.</p>
    Formula:C18H31NO4
    Color and Shape:Solid
    Molecular weight:325.44