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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 958 products of "DNA Damage/DNA Repair"

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  • TAK1 inhibitor

    CAS:
    <p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>
    Formula:C22H19ClN6O2S
    Purity:98%
    Color and Shape:Soild
    Molecular weight:466.94
  • (±)4(5)-DiHDPA lactone

    CAS:
    <p>(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5</p>
    Formula:C22H32O3
    Color and Shape:Solid
    Molecular weight:344.495
  • SMPB Crosslinker

    CAS:
    <p>SMPB crosslinker reacts with sulfhydryl/amino groups, has a longer chain than MBS, and a non-cleavable spacer arm.</p>
    Formula:C18H16N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.33
  • CAY10599

    CAS:
    <p>CAY10599 has a wide range of applications in life science related research.</p>
    Formula:C38H41NO5
    Color and Shape:Solid
    Molecular weight:591.748
  • WAY-323061

    CAS:
    <p>WAY-323061 is a SIRT2 inhibitor.</p>
    Formula:C25H21N5O2S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:455.53
  • NHC-triphosphate tetrasodium


    <p>NHC-triphosphate tetrasodium, a metabolite of β-d-N4-Hydroxycytidine, acts as a viral polymerase substrate affecting HCV RNA replication.</p>
    Formula:C9H12N3Na4O15P3
    Color and Shape:Solid
    Molecular weight:587.08
  • Tibesaikosaponin V

    CAS:
    <p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>
    Formula:C42H68O15
    Color and Shape:Solid
    Molecular weight:812.98
  • DNMT1/HDAC-IN-1


    <p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>
    Color and Shape:Odour Solid
  • GJ071 oxalate

    CAS:
    <p>GJ071 oxalate is a Nonsense suppressor that induces readthrough by inserting amino acids at premature termination codons.</p>
    Formula:C20H29N3O7S
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:455.53
  • DNA Damage & Repair Compound Library


    <p>A unique collection of xnum DNA Damage &amp;amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>
    Color and Shape:Odour Solid
  • Z26395438

    CAS:
    <p>Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.</p>
    Formula:C17H15FN2O
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:282.31
  • SJ-106C


    <p>SJ-106C, a SIRT inhibitor, exhibits IC50 values of 0.59, 0.12, and 0.49 μM against SIRT1/2/3, respectively. This compound specifically targets mitochondria and inhibits the growth of DLBCL tumors.</p>
    Color and Shape:Odour Solid
  • Hippeastrine

    CAS:
    <p>Hippeastrine is an alkaloid that inhibits Top I dose-dependently with a 7.25 μg/mL IC50 and has anticancer properties.</p>
    Formula:C17H17NO5
    Color and Shape:Solid
    Molecular weight:315.32
  • CP 84364

    CAS:
    <p>CP 84364 is a metabolite of CP-80794.</p>
    Formula:C14H18N2O4
    Color and Shape:Solid
    Molecular weight:278.30
  • CUDA disodium


    <p>CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.</p>
    Color and Shape:Odour Solid
  • SP4e


    <p>SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.</p>
    Formula:C22H17ClN2O2S2
    Purity:99.79%
    Color and Shape:Soild
    Molecular weight:440.97
  • Methylation Compound Library


    <p>xnum methylation-related compounds that can be used for high-throughput and high-content screening.</p>
    Color and Shape:Odour Solid
  • HDAC-IN-78


    <p>HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.</p>
    Color and Shape:Odour Solid
  • (±)9-HEPE

    CAS:
    <p>(±)9-HEPE is produced by non-enzymatic oxidation of EPA.</p>
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.457
  • NHC-diphosphate triammonium


    <p>NHC-triphosphate triammonium is a phosphorylated metabolite of NHC, incorporated into HCV RNA by viral polymerase.</p>
    Color and Shape:Solid