CymitQuimica logo
DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

Show 3 more subcategories

Found 958 products of "DNA Damage/DNA Repair"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • NC190 sodium
    Targetmol
    + Info

    NC190 sodium

    CAS:
    <p>NC190 inhibits topoisomerase II, halts FM3A cell growth (IC50: 0.019 μg/ml in 48h), and suppresses DNA synthesis by 90% at 0.1 μg/ml.</p>
    Formula:C23H22N4NaO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:457.442

    Ref: TM-T25857

  • BMS-711939
    Targetmol
    + Info

    BMS-711939

    CAS:
    <p>BMS-711939: Potent PPARα agonist, EC50=4 nM, shown effective and safe in preclinical trials.</p>
    Formula:C22H20ClFN2O6
    Color and Shape:Solid
    Molecular weight:462.86

    Ref: TM-T30539

  • NHC-triphosphate
    Targetmol
    + Info

    NHC-triphosphate

    CAS:
    <p>NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels.</p>
    Formula:C9H16N3O15P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:499.16

    Ref: TM-T19476

  • Topoisomerase IIα-IN-2
    Targetmol
    + Info

    Topoisomerase IIα-IN-2

    CAS:
    <p>Topoisomerase IIα-IN-2 (compound 5) is a DNA-binding ligands and a potent inhibitor of the topoisomerase TopoIIα.</p>
    Formula:C22H20N4O5
    Color and Shape:Solid
    Molecular weight:420.42

    Ref: TM-T62224

  • Naveglitazar
    Targetmol
    + Info

    Naveglitazar

    CAS:
    <p>Naveglitazar (LY 519818, LY 9818), a PPAR modulator in phase II trials for type 2 diabetes.</p>
    Formula:C25H26O6
    Color and Shape:Solid
    Molecular weight:422.47

    Ref: TM-T33598

  • LY-510929
    Targetmol
    + Info

    LY-510929

    CAS:
    <p>LY-510929: PPAR agonist for hyperlipidemia, metabolic issues, type 2 diabetes.</p>
    Formula:C26H25NO5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:463.55

    Ref: TM-T27960

  • HWL-088
    Targetmol
    + Info

    HWL-088

    CAS:
    <p>HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.</p>
    Formula:C22H19FO4
    Color and Shape:Solid
    Molecular weight:366.38

    Ref: TM-T11583

  • CCT128930
    Targetmol
    + Info

    CCT128930

    CAS:
    <p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>
    Formula:C18H20ClN5
    Purity:99.07% - 99.18%
    Color and Shape:Solid
    Molecular weight:341.84

    Ref: TM-T6303

  • PluriSIn #2
    Targetmol
    + Info

    PluriSIn #2

    CAS:
    <p>PluriSIn #2 is a selective topoisomerase II α (topo2α) transcription inhibitor exhibiting cytotoxicity towards undifferentiated, leukaemogenic hPSCs.</p>
    Formula:C11H8FN3O3
    Purity:98% - 99.79%
    Color and Shape:Solid
    Molecular weight:249.2

    Ref: TM-T36301

  • HDAC-IN-5
    Targetmol
    + Info

    HDAC-IN-5

    CAS:
    <p>HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.</p>
    Formula:C26H24F3N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:527.56

    Ref: TM-T11543

  • Ertiprotafib
    Targetmol
    + Info

    Ertiprotafib

    CAS:
    <p>Ertiprotafib (PTP 112), a PTP1B and IKK-β inhibitor, is a novel insulin sensitizer for the study of type 2 diabetes and breast cancer.</p>
    Formula:C31H27BrO3S
    Purity:98.70%
    Color and Shape:Solid
    Molecular weight:559.51

    Ref: TM-T15243

  • Sirt2-IN-1
    Targetmol
    + Info

    Sirt2-IN-1

    CAS:
    <p>Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).</p>
    Formula:C28H27N7O2S2
    Purity:99.57% - 99.84%
    Color and Shape:Solid
    Molecular weight:557.69

    Ref: TM-T12920

  • CAY10767
    Targetmol
    + Info

    CAY10767

    CAS:
    <p>CAY10767 is a PPARα agonist with an EC50 of 37 nM; over 2700x selective against PPARγ/δ.</p>
    Formula:C22H20FNO3
    Color and Shape:Solid
    Molecular weight:365.4

    Ref: TM-T37833

  • Guadecitabine sodium
    Targetmol
    + Info

    Guadecitabine sodium

    CAS:
    <p>Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .</p>
    Formula:C18H24N9NaO10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:580.407

    Ref: TM-T12790

  • Topoisomerase I inhibitor 7
    Targetmol
    + Info

    Topoisomerase I inhibitor 7

    CAS:
    <p>Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I.</p>
    Formula:C22H19N3O5
    Color and Shape:Solid
    Molecular weight:405.4

    Ref: TM-T62002

  • LG100754
    Targetmol
    + Info

    LG100754

    CAS:
    <p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>
    Formula:C26H36O3
    Color and Shape:Solid
    Molecular weight:396.56

    Ref: TM-T15748

  • 9-Hydroxyellipticine hydrochloride
    Targetmol
    + Info

    9-Hydroxyellipticine hydrochloride

    CAS:
    <p>9-Hydroxyellipticine hydrochloride is an inhibitor of Topo II and RyR, exhibits antitumor and antileukemic activity, and inhibits carrageenan gum-induced edema.</p>
    Formula:C17H15ClN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:298.77

    Ref: TM-T10200

  • Topoisomerase II inhibitor 16
    Targetmol
    + Info

    Topoisomerase II inhibitor 16

    CAS:
    <p>Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the</p>
    Formula:C19H12F4N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:416.33

    Ref: TM-T79539

  • Topoisomerase IV inhibitor 1
    Targetmol
    + Info

    Topoisomerase IV inhibitor 1

    CAS:
    <p>Compound 7d: Inhibits TOPO IV (IC50: 0.23 μM), DNA gyrase (IC50: 0.43 μM), antibacterial against S. aureus (MIC: 0.972 μM), E. coli (MIC: 0.608 μM).</p>
    Formula:C34H32FN7O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:685.72

    Ref: TM-T72153

  • PB131
    Targetmol
    + Info

    PB131

    CAS:
    <p>PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitable</p>
    Formula:C16H16FN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:301.32

    Ref: TM-T78969

  • GW 9578
    Targetmol
    + Info

    GW 9578

    CAS:
    <p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>
    Formula:C26H34F2N2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.62

    Ref: TM-T27519

  • Chiglitazar
    Targetmol
    + Info

    Chiglitazar

    CAS:
    <p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>
    Formula:C36H29FN2O4
    Color and Shape:Solid
    Molecular weight:572.63

    Ref: TM-T14948

  • HDAC-IN-58
    Targetmol
    + Info

    HDAC-IN-58

    CAS:
    <p>HDAC-IN-58, a selective HDAC6 inhibitor, exhibits potent inhibitory activity with an IC50 of 2.06 nM, rendering it suitable for research into chronic</p>
    Formula:C16H13ClF2N4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.81

    Ref: TM-T78920

  • Topoisomerase IV inhibitor 2
    Targetmol
    + Info

    Topoisomerase IV inhibitor 2

    CAS:
    <p>Compound 5d, a potent TOPO IV inhibitor (IC50: 0.35 μM), also inhibits DNA gyrase (IC50: 0.55 μM) and has antibacterial activity.</p>
    Formula:C33H30FN7O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:671.7

    Ref: TM-T72154

  • HDAC ligand-1
    Targetmol
    + Info

    HDAC ligand-1

    CAS:
    <p>HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].</p>
    Formula:C7H8N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:136.15

    Ref: TM-T79003

  • ATR-IN-23
    Targetmol
    + Info

    ATR-IN-23

    CAS:
    <p>ATR-IN-23 (Compound 34), a potent and selective ATR inhibitor, exhibits an IC50 of 1.5 nM, has demonstrated antiproliferative effects on LoVo cells, and induces</p>
    Formula:C20H22N6O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:458.56

    Ref: TM-T78959

  • BRD 9757
    Targetmol
    + Info

    BRD 9757

    CAS:
    <p>BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).</p>
    Formula:C6H9NO2
    Purity:98.39% - 99.87%
    Color and Shape:Solid
    Molecular weight:127.14

    Ref: TM-T25175

  • NSC16168
    Targetmol
    + Info

    NSC16168

    CAS:
    <p>NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.</p>
    Formula:C17H15NO9S3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:473.5

    Ref: TM-T16351

  • Dehydroepiandrosterone sulfate
    Targetmol
    + Info

    Dehydroepiandrosterone sulfate

    CAS:
    <p>Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.</p>
    Formula:C19H28O5S
    Purity:97.18%
    Color and Shape:Solid
    Molecular weight:368.49

    Ref: TM-T26366

  • ISX-1
    Targetmol
    + Info

    ISX-1

    CAS:
    <p>ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia.</p>
    Formula:C14H14N4O2S
    Purity:98.7%
    Color and Shape:Solid
    Molecular weight:302.35

    Ref: TM-T24182

  • Linotroban
    Targetmol
    + Info

    Linotroban

    CAS:
    <p>Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>
    Formula:C14H15NO5S2
    Purity:97.95% - >99.99%
    Color and Shape:Solid
    Molecular weight:341.4

    Ref: TM-T25741

  • Dazmegrel
    Targetmol
    + Info

    Dazmegrel

    CAS:
    <p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>
    Formula:C16H17N3O2
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:283.33

    Ref: TM-T31213

  • Vutiglabridin
    Targetmol
    + Info

    Vutiglabridin

    CAS:
    <p>Vutiglabridin (HSG4112), a PON2 modulator, is more stable and aids weight loss than Glabridin. In phase 2 trials for obesity, shows promise for PD therapy.</p>
    Formula:C22H26O4
    Purity:98.47% - 99.07%
    Color and Shape:Solid
    Molecular weight:354.44

    Ref: TM-T61268

  • Chloroquinoxaline sulfonamide
    Targetmol
    + Info

    Chloroquinoxaline sulfonamide

    CAS:
    <p>Chloroquinoxaline sulfonamide (Chloroquinoxaline) is an organic micropollutant with antimicrobial activity.</p>
    Formula:C14H11ClN4O2S
    Purity:99.79% - 99.89%
    Color and Shape:Solid
    Molecular weight:334.78

    Ref: TM-T14953

  • DN-1289
    Targetmol
    + Info

    DN-1289

    <p>DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) &amp; LZK (IC50=40nM), blocks p-c-Jun in mouse optic nerve crush.</p>
    Formula:C18H19F4N7O2
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:441.38

    Ref: TM-T73457

  • SIRT5 inhibitor 1
    Targetmol
    + Info

    SIRT5 inhibitor 1

    CAS:
    <p>SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.</p>
    Formula:C31H39FN6O6S2
    Purity:97.8%
    Color and Shape:Solid
    Molecular weight:674.81

    Ref: TM-T12921

  • Cedazuridine
    Targetmol
    + Info

    Cedazuridine

    CAS:
    <p>Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.</p>
    Formula:C9H14F2N2O5
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:268.21

    Ref: TM-T26972

  • AGI-24512
    Targetmol
    + Info

    AGI-24512

    CAS:
    <p>AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in</p>
    Formula:C24H24N4O2
    Purity:98.55%
    Color and Shape:Solid
    Molecular weight:400.47

    Ref: TM-T14141

  • Procainamide
    Targetmol
    + Info

    Procainamide

    CAS:
    <p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>
    Formula:C13H21N3O
    Purity:99.92% - 99.92%
    Color and Shape:Solid
    Molecular weight:235.33

    Ref: TM-T60322

  • L82
    Targetmol
    + Info

    L82

    CAS:
    <p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>
    Formula:C11H8ClN5O4
    Purity:97.45% - 98.91%
    Color and Shape:Solid
    Molecular weight:309.67

    Ref: TM-T60753

  • BTB09089
    Targetmol
    + Info

    BTB09089

    CAS:
    <p>BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production</p>
    Formula:C14H12Cl2N4OS2
    Purity:99.78%
    Color and Shape:Soild
    Molecular weight:387.31

    Ref: TM-T67892

  • SIRT6-IN-5
    Targetmol
    + Info

    SIRT6-IN-5

    CAS:
    <p>SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.</p>
    Formula:C19H14N2O6
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:366.32

    Ref: TM-T24793

  • HDAC8-IN-20a
    Targetmol
    + Info

    HDAC8-IN-20a

    CAS:
    <p>HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.</p>
    Formula:C15H15NO4
    Purity:98.24% - 99.22%
    Color and Shape:Solid
    Molecular weight:273.28

    Ref: TM-T24133

  • Suksdorfin
    Targetmol
    + Info

    Suksdorfin

    CAS:
    <p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>
    Formula:C21H24O7
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:388.41

    Ref: TM-T69146

  • Bobcat339 hydrochloride
    Targetmol
    + Info

    Bobcat339 hydrochloride

    CAS:
    <p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>
    Formula:C16H13Cl2N3O
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:334.2

    Ref: TM-T61012

  • Alalevonadifloxacin
    Targetmol
    + Info

    Alalevonadifloxacin

    CAS:
    <p>Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa.</p>
    Formula:C23H30FN3O8S
    Purity:99.75% - 99.82%
    Color and Shape:Soild
    Molecular weight:527.56

    Ref: TM-T67826

  • Pegamotecan
    Targetmol
    + Info

    Pegamotecan

    CAS:
    <p>Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell</p>
    Formula:C52H48N6O14
    Purity:96.40% - 97.83%
    Color and Shape:Solid
    Molecular weight:980.984

    Ref: TM-T24610

  • Miriplatin hydrate
    Targetmol
    + Info

    Miriplatin hydrate

    CAS:
    Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).
    Formula:C34H70N2O5Pt
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:782.01

    Ref: TM-T21297

  • BRD6688
    Targetmol
    + Info

    BRD6688

    CAS:
    <p>BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes</p>
    Formula:C16H18N4O
    Purity:97.53%
    Color and Shape:Solid
    Molecular weight:282.34

    Ref: TM-T21715

  • PARP10-IN-2
    Targetmol
    + Info

    PARP10-IN-2

    CAS:
    <p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>
    Formula:C14H10N2O2
    Purity:99.27%
    Color and Shape:Solid
    Molecular weight:238.24

    Ref: TM-T73007