DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
9-Chloromethyl-10-hydroxy-11-F-Camptothecin
CAS:2414594-22-0
9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor …
Formula:
C22H18ClFN2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
428.84
Ref: TM-T79883
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
MDL-811
CAS:2275619-98-0
MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine …
Formula:
C25H25BrCl2FN3O5S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
681.42
Ref: TM-T81831
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Sirt1/2-IN-3
CAS:301313-42-8
Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 …
Formula:
C17H14ClNO4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
363.82
Ref: TM-T79564
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Tankyrase-IN-5
CAS:1460285-69-1
Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with …
Formula:
C17H18N2O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
282.34
Ref: TM-T79026
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
PARP7-IN-15
CAS:2819998-97-3
PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and …
Formula:
C23H24F6N6O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
562.46
Ref: TM-T81542
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Epigenetic factor-IN-1
CAS:2640673-56-7
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.
Formula:
C32H34FN5O6S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
667.77
Ref: TM-T82458
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Trovafloxacin mesylate
CAS:147059-75-4
Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
Formula:
C21H19F3N4O6S
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
512.46
Ref: TM-T13231L
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 537.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
SRT3657
CAS:1383551-17-4
SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.
Formula:
C40H54N8O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
774.97
Ref: TM-T13001
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
NH2-methylpropanamide-Exatecan TFA
CAS:1817857-35-4
Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA …
Formula:
C30H30F4N4O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
634.58
Ref: TM-T77889
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS:101515-08-6
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value …
Formula:
C11H17N4O13P3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
506.19
Ref: TM-T83248
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
SIRT6-IN-3
CAS:3023471-40-8
SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of …
Formula:
C21H30Br3ClN6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
673.73
Ref: TM-T79689
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Sirtuin modulator 1
CAS:2070015-26-6
Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.
Formula:
C31H32ClN5O2S2
Purity:
99.1%
Color and Shape:
Solid
Molecular weight:
606.2
Ref: TM-T12922
| 5mg | 36.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 89.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
ATR-IN-21
CAS:2905312-17-4
ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 …
Formula:
C23H27N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
417.51
Ref: TM-T79031
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Topoisomerase II inhibitor 15
CAS:451516-79-3
Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity …
Formula:
C15H11Cl2N5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
332.19
Ref: TM-T79506
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Tefinostat
CAS:914382-60-8
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor.
Formula:
C28H37N3O5
Purity:
99.41%
Color and Shape:
Solid
Molecular weight:
495.61
Ref: TM-T17028
| 1mg | 94.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 330.00 € | ||
| 25mg | 537.00 € | ||
| 50mg | 736.00 € | ||
| 100mg | 1,039.00 € | ||
| 1mL*10mM (DMSO) | 240.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Camonsertib
CAS:2417489-10-0
Camonsertib (RP-3500) is a novel, potent and selective ATR kinase inhibitor (ATRi) that exhibits potent …
Formula:
C21H26N6O3
Purity:
98.15% - 99.6%
Color and Shape:
Liquid
Molecular weight:
410.47
Ref: TM-T62083
| 1mg | 166.00 € | ||
| 5mg | 407.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,225.00 € | ||
| 100mg | 1,689.00 € | ||
| 1mL*10mM (DMSO) | 460.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
DNA-PK-IN-10
CAS:2919315-89-0
DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell …
Formula:
C25H28N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
444.53
Ref: TM-T79165
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
HDAC1/CDK7-IN-1
CAS:2987905-95-1
HDAC1/CDK7-IN-1 (compound 8e) serves as a dual inhibitor targeting both CDK7 and HDAC1, with IC50 …
Formula:
C33H32ClN7O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
626.11
Ref: TM-T82227
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Topoisomerase I inhibitor 9
CAS:1228150-86-4
Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial …
Formula:
C23H15Br2FN2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
498.19
Ref: TM-T80967
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
SP-2-225
CAS:2364448-93-9
SP-2-225, a selective inhibitor of HDAC6, augments the production of cancer-associated antigens and enhances macrophage …
Formula:
C28H34N2O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
446.58
Ref: TM-T79366
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
