DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
(S)-Seco-Duocarmycin SA
CAS:152785-82-5
(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can …
Formula:
C25H24ClN3O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
513.93
Ref: TM-T12813
| 25mg | 2,106.00 € | ||
| 50mg | 2,787.00 € | ||
| 100mg | 3,741.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
DRF-1042
CAS:200619-13-2
DRF-1042 is a camptothecin analog with anticancer and insecticidal activity and is used to study …
Formula:
C22H20N2O6
Purity:
97.00%
Color and Shape:
Solid
Molecular weight:
408.4
Ref: TM-T15168
| 1mg | 36.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 527.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Intoplicine
CAS:125974-72-3
Intoplicine is an inhibitor of DNA topoisomerase I and II.
Formula:
C21H24N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
348.44
Ref: TM-T15586
| 25mg | 2,106.00 € | ||
| 50mg | 2,776.00 € | ||
| 100mg | 3,726.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Seco-Duocarmycin SA
CAS:144667-38-9
Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.
Formula:
C25H24ClN3O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
513.93
Ref: TM-T12813L
| 25mg | 2,106.00 € | ||
| 50mg | 2,785.00 € | ||
| 100mg | 3,739.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
HDAC8-IN-12
CAS:3028095-13-5
HDAC8-IN-12 (compound 5k), a non-hydroxamic acid derivative, serves as a selective HDAC8 inhibitor with an …
Formula:
C16H17N3O5
Color and Shape:
Liquid
Molecular weight:
331.32
Ref: TM-T200383
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
DLK-IN-1
CAS:1620574-24-4
DLK-IN-1: Oral DLK (MAP3K12) inhibitor, Ki=3nM, effective in Alzheimer's model, CNS permeable, well-tolerated with sustained …
Formula:
C20H24F3N5O2
Color and Shape:
Solid
Molecular weight:
423.43
Ref: TM-T11056
| 5mg | 490.00 € | ||
| 25mg | 1,623.00 € | ||
| 50mg | 2,134.00 € | ||
| 100mg | 3,061.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Edotecarin
CAS:174402-32-5
Edotecarin is a potent topoisomerase I inhibitor. It can decrease single-strand DNA cleavage (IC50: 50 …
Formula:
C29H28N4O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
608.55
Ref: TM-T15200
| 25mg | 2,106.00 € | ||
| 50mg | 2,785.00 € | ||
| 100mg | 3,739.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
TMU 35435
CAS:2231800-32-9
TMU 35435 is an inhibitor of histone deacetylases (HDAC). It enhances radiosensitivity by inducing the …
Formula:
C22H25N3O3
Color and Shape:
Liquid
Molecular weight:
379.45
Ref: TM-T200171
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
G-631
CAS:1507370-78-6
G-631 acts as a selective tankyrase inhibitor, effectively hindering tankyrase auto-PARsylation (poly ADP ribosylation) at …
Formula:
C19H22F2N6O3
Color and Shape:
Liquid
Molecular weight:
420.41
Ref: TM-T200085
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Gimatecan
CAS:292618-32-7
Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue …
Formula:
C25H25N3O5
Purity:
98.47%
Color and Shape:
Solid
Molecular weight:
447.48
Ref: TM-T21319
| 1mg | 112.00 € | ||
| 5mg | 268.00 € | ||
| 10mg | 444.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,007.00 € | ||
| 1mL*10mM (DMSO) | 301.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Simmitecan hydrochloride
CAS:1247847-78-4
Simmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can …
Formula:
C34H39ClN4O6
Purity:
98.20% - 98.36%
Color and Shape:
Liquid
Molecular weight:
635.15
Ref: TM-T71137
| 1mg | 555.00 € | ||
| 5mg | 1,207.00 € | ||
| 25mg | 2,423.00 € | ||
| 50mg | 3,187.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
ATM Inhibitor-1
CAS:2135639-94-8
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) …
Formula:
C27H36N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
492.61
Ref: TM-T10396
| 25mg | 2,245.00 € | ||
| 50mg | 2,963.00 € | ||
| 100mg | 4,006.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
KU-60019
CAS:925701-46-8
KU-60019 is a specific inhibitor of ATM kinase (IC50: 6.3 nM).
Formula:
C30H33N3O5S
Purity:
97.15%
Color and Shape:
Liquid
Molecular weight:
547.67
Ref: TM-T63872
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 511.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Karenitecin
CAS:203923-89-1
Karenitecin (Cositecan) is an inhibitor of topoisomerase I. It has potent anti-cancer activity.
Formula:
C25H28N2O4Si
Purity:
98%
Color and Shape:
Solid
Molecular weight:
448.59
Ref: TM-T14703
| 25mg | 1,419.00 € | ||
| 50mg | 1,854.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Antibacterial agent 236
CAS:2364479-10-5
Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase …
Formula:
C26H27N5O2S
Color and Shape:
Liquid
Molecular weight:
473.59
Ref: TM-T200041
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
BAY-8400
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor …
Formula:
C21H17F2N5O
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
393.39
Ref: TM-T9498
| 1mg | 82.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 447.00 € | ||
| 50mg | 762.00 € | ||
| 100mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 25 Mar 2025
Buddlejasaponin IV
CAS:139523-30-1
Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, …
Formula:
C48H78O18
Purity:
98%
Color and Shape:
Solid
Molecular weight:
943.12
Ref: TM-TN1458
| 1ml | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
Nedisertib
CAS:1637542-33-6
Nedisertib (M3814) (M3814) is a specific inhibitor of DNA-dependent Protein Kinase (DNA-PK, IC50: <3 nM).
Formula:
C24H21ClFN5O3
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
481.91
Ref: TM-TQ0031
| 1mg | Discontinued | Request information | |
| 1ml | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
(Rac)-Nedisertib
CAS:1637542-34-7
(Rac)-Nedisertib is a racemate of Nedisertib, a potent inhibitor of DNA-PK(IC50 of <3 nM).
Formula:
C24H21ClFN5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
481.91
Ref: TM-T12672
| 5mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information |
Mefuparib hydrochloride
CAS:1449746-00-2
Mefuparib hydrochloride (MPH), an oral PARP1/2 inhibitor, induces apoptosis with strong anticancer effects; IC50: 3.2 …
Formula:
C17H16ClFN2O2
Color and Shape:
Solid
Molecular weight:
334.77
Ref: TM-T11992
| 1mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information |
