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DNA Methyltransferase

DNA Methyltransferase

DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.

Found 422 products of "DNA Methyltransferase"

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  • UNC6934
    Targetmol
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    UNC6934

    CAS:
    <p>UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.</p>
    Formula:C24H21N5O4
    Purity:98.67%
    Color and Shape:Solid
    Molecular weight:443.45

    Ref: TM-T9584

  • Amodiaquine hydrochloride
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    Amodiaquine hydrochloride

    CAS:
    <p>Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.</p>
    Formula:C20H24Cl3N3O
    Color and Shape:Solid
    Molecular weight:428.78

    Ref: TM-T22242

  • UNC3866
    Targetmol
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    UNC3866

    CAS:
    <p>UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>
    Formula:C43H66N6O8
    Purity:88.06% - 99.62%
    Color and Shape:Solid
    Molecular weight:795.02

    Ref: TM-T4021

  • UNC0642
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    UNC0642

    CAS:
    <p>UNC0642 is an effective and specific G9a/GLP inhibitor (IC50&lt; 2.5 nM).</p>
    Formula:C29H44F2N6O2
    Purity:98.75% - 99.5%
    Color and Shape:Solid
    Molecular weight:546.7

    Ref: TM-T4166

  • MR837
    Targetmol
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    MR837

    CAS:
    <p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>
    Formula:C16H14N2OS
    Purity:99.77% - 99.85%
    Color and Shape:Solid
    Molecular weight:282.36

    Ref: TM-T8879

  • Hinokitiol
    Targetmol
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    Hinokitiol

    CAS:
    Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.
    Formula:C10H12O2
    Purity:99.49% - 99.98%
    Color and Shape:Solid
    Molecular weight:164.2

    Ref: TM-T3717

  • UNC0379
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    UNC0379

    CAS:
    <p>UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.</p>
    Formula:C23H35N5O2
    Purity:94.41% - 99.97%
    Color and Shape:Solid
    Molecular weight:413.56

    Ref: TM-T1841

  • MS023
    Targetmol
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    MS023

    CAS:
    <p>MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,</p>
    Formula:C17H25N3O
    Purity:98.31% - 99.87%
    Color and Shape:Solid
    Molecular weight:287.4

    Ref: TM-T6900

  • 5-Fluoro-2'-deoxycytidine
    Targetmol
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    5-Fluoro-2'-deoxycytidine

    CAS:
    <p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>
    Formula:C9H12FN3O4
    Purity:97.91%
    Color and Shape:Fine White Powder
    Molecular weight:245.21

    Ref: TM-T7718

  • SGC2085
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    SGC2085

    CAS:
    <p>SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).</p>
    Formula:C19H24N2O2
    Purity:99.61% - 99.71%
    Color and Shape:Solid
    Molecular weight:312.41

    Ref: TM-T7089

  • Bobcat339
    Targetmol
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    Bobcat339

    CAS:
    <p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>
    Formula:C16H12ClN3O
    Purity:97.79% - 99.24%
    Color and Shape:Solid
    Molecular weight:297.74

    Ref: TM-T5198

  • EPZ004777 hydrochloride
    Targetmol
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    EPZ004777 hydrochloride

    CAS:
    <p>EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>
    Formula:C28H42ClN7O4
    Color and Shape:Solid
    Molecular weight:576.13

    Ref: TM-T3081L

  • MRTX-1719
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    MRTX-1719

    CAS:
    <p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of &lt;10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>
    Formula:C23H18ClFN6O2
    Purity:98.27% - 99.18%
    Color and Shape:Solid
    Molecular weight:464.88

    Ref: TM-T40254

  • MS37452
    Targetmol
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    MS37452

    CAS:
    <p>MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).</p>
    Formula:C22H26N2O5
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:398.45

    Ref: TM-T21767

  • DCLX069
    Targetmol
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    DCLX069

    CAS:
    <p>DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.</p>
    Formula:C20H25N3O2
    Purity:97.76%
    Color and Shape:Solid
    Molecular weight:339.43

    Ref: TM-T27133

  • GSK503
    Targetmol
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    GSK503

    CAS:
    <p>GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.</p>
    Formula:C31H38N6O2
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:526.67

    Ref: TM-T1775

  • EPZ011989
    Targetmol
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    EPZ011989

    CAS:
    <p>EPZ011989: potent, selective oral EZH2 inhibitor, Ki &lt; 3 nM, 15x more selective than EZH1, &gt;3000x over other HMTases.</p>
    Formula:C35H51N5O4
    Purity:98% - 99.45%
    Color and Shape:Solid
    Molecular weight:605.81

    Ref: TM-T2435

  • GSK343
    Targetmol
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    GSK343

    CAS:
    <p>GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and &gt;1000 fold specificity activity against</p>
    Formula:C31H39N7O2
    Purity:98% - 99.9%
    Color and Shape:Solid
    Molecular weight:541.69

    Ref: TM-T6059

  • 6-Thioguanine
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    6-Thioguanine

    CAS:
    <p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>
    Formula:C5H5N5S
    Purity:98.34% - >99.99%
    Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline Powder
    Molecular weight:167.19

    Ref: TM-T3089

  • γ-Oryzanol
    Targetmol
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    γ-Oryzanol

    CAS:
    <p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>
    Formula:C40H58O4
    Purity:mixture - mixture
    Color and Shape:White Or White Crystalline Powder Odourless
    Molecular weight:602.9

    Ref: TM-T3606