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DNA Methyltransferase

DNA Methyltransferase

DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.

Found 422 products of "DNA Methyltransferase"

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  • GSK591
    Targetmol
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    GSK591

    CAS:
    <p>GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).</p>
    Formula:C22H28N4O2
    Purity:99.35% - 99.45%
    Color and Shape:Solid
    Molecular weight:380.48

    Ref: TM-T6853

  • Succinic acid sodium
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    Succinic acid sodium

    CAS:
    <p>Succinic acid sodium is an orally active anxiolytic.</p>
    Formula:C4H6O4·xNa
    Color and Shape:Solid

    Ref: TM-T64294

  • Piribedil
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    Piribedil

    CAS:
    Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
    Formula:C16H18N4O2
    Purity:99.79% - 99.82%
    Color and Shape:Solid
    Molecular weight:298.34

    Ref: TM-T3278

  • CM-272
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    CM-272

    CAS:
    CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
    Formula:C28H38N4O3
    Purity:97.83%
    Color and Shape:Solid
    Molecular weight:478.63

    Ref: TM-T7194

  • 3-deazaneplanocin A HCl
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    3-deazaneplanocin A HCl

    CAS:
    <p>3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.</p>
    Formula:C12H15ClN4O3
    Purity:93.24% - 98.9%
    Color and Shape:Solid
    Molecular weight:298.73

    Ref: TM-T6360

  • UNC3866 TFA(1872382-47-2 free base)
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    UNC3866 TFA(1872382-47-2 free base)

    CAS:
    <p>UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>
    Formula:C45H67F3N6O10
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:909.04

    Ref: TM-T4021L

  • EPZ005687
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    EPZ005687

    CAS:
    EPZ005687 is a potent and selective inhibitor of EZH2.
    Formula:C32H37N5O3
    Purity:97.06% - 99.64%
    Color and Shape:Solid
    Molecular weight:539.67

    Ref: TM-T1905

  • Amodiaquine
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    Amodiaquine

    CAS:
    <p>Amodiaquine is a synthetic aminoquinoline, used to treat malaria.</p>
    Formula:C20H22ClN3O
    Purity:99.78% - 99.99%
    Color and Shape:Crystals From Absolute Ethanol Solid
    Molecular weight:355.86

    Ref: TM-T8381

  • GSK3685032
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    GSK3685032

    CAS:
    <p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>
    Formula:C22H24N6OS
    Purity:98.56% - 99.49%
    Color and Shape:Solid
    Molecular weight:420.53

    Ref: TM-T9573

  • CymitQuimica logo
    Targetmol
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    SETDB1-TTD-IN-1 TFA

    <p>SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.</p>
    Formula:C30H32F3N5O4
    Color and Shape:Solid
    Molecular weight:583.6

    Ref: TM-T64120

  • GSK126
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    GSK126

    CAS:
    <p>GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).</p>
    Formula:C31H38N6O2
    Purity:98% - 99.67%
    Color and Shape:Solid
    Molecular weight:526.67

    Ref: TM-T2079

  • EED226
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    EED226

    CAS:
    <p>EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.</p>
    Formula:C17H15N5O3S
    Purity:98.14% - 99.33%
    Color and Shape:Solid
    Molecular weight:369.4

    Ref: TM-T3458

  • GSK3326595
    Targetmol
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    GSK3326595

    CAS:
    <p>GSK3326595 (EPZ015938) is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.).</p>
    Formula:C24H32N6O3
    Purity:97.7% - 99.63%
    Color and Shape:Solid
    Molecular weight:452.55

    Ref: TM-T5745

  • A-196
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    A-196

    CAS:
    <p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>
    Formula:C18H16Cl2N4
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:359.25

    Ref: TM-T4343

  • JNJ-64619178
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    JNJ-64619178

    CAS:
    <p>JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.</p>
    Formula:C22H23BrN6O2
    Purity:98.44% - 99.63%
    Color and Shape:Solid
    Molecular weight:483.36

    Ref: TM-T15624

  • MM-102 TFA
    Targetmol
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    MM-102 TFA

    CAS:
    <p>MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.</p>
    Formula:C37H50F5N7O6
    Purity:99.4% - 99.78%
    Color and Shape:Solid
    Molecular weight:783.83

    Ref: TM-T8768

  • JQEZ5
    Targetmol
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    JQEZ5

    CAS:
    <p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>
    Formula:C30H38N8O2
    Purity:98.14% - ≥98%
    Color and Shape:Solid
    Molecular weight:542.68

    Ref: TM-T7305

  • WDR5-0103
    Targetmol
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    WDR5-0103

    CAS:
    WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).
    Formula:C21H25N3O4
    Purity:98% - 99.61%
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T3201

  • C-7280948
    Targetmol
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    C-7280948

    CAS:
    <p>C-7280948 is a PRMT1 inhibitor.</p>
    Formula:C14H16N2O2S
    Purity:99.55% - ≥95%
    Color and Shape:Solid
    Molecular weight:276.35

    Ref: TM-T2097

  • MIV-6R
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    MIV-6R

    CAS:
    <p>MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.</p>
    Formula:C27H35N3O
    Purity:99.81% - 99.88%
    Color and Shape:Solid
    Molecular weight:417.59

    Ref: TM-T24472