DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
Found 472 products for "DNA Methyltransferase".
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MAK683
CAS:MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).Formula:C20H17FN6OPurity:98.43% - 99.92%Color and Shape:SolidMolecular weight:376.39BVT948
CAS:BVT948 is a protein tyrosine phosphatase (PTP) inhibitor.It can also inhibit lysine methyltransferase SETD8 (KMT5A) and several cytochrome P450 (P450) isoforms.Formula:C14H11NO3Purity:98.87%Color and Shape:Red SolidMolecular weight:241.24Ref: TM-T14841
1mg35.00€2mg50.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg99.00€25mg148.00€50mg200.00€100mg319.00€EBI-2511
CAS:EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines).Formula:C34H48N4O4Purity:99.74%Color and Shape:SolidMolecular weight:576.77(1S,3R,4R,5R)-3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid
CAS:Formula:C16H18O9Purity:95%Color and Shape:SolidMolecular weight:354.3087Ref: IN-DA00I681
50kgTo inquire1g20.00€250mg20.00€5g40.00€10g59.00€25g106.00€50g160.00€100g215.00€1kg901.00€Hydralazine hydrochloride
CAS:Formula:C8H9ClN4Purity:98%Color and Shape:SolidMolecular weight:196.6369Amodiaquine dihydrochloride dihydrate
CAS:Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory effectsFormula:C20H28Cl3N3O3Purity:99.97%Color and Shape:SolidMolecular weight:464.82Diperodon hydrochloride
CAS:Diperodon hydrochloride (Diperocaine) is a local anesthetic that can be broken down by serolytic enzymes to produce local anesthetic effects.Formula:C22H28ClN3O4Purity:99.91%Color and Shape:White SolidMolecular weight:433.93DC-05
CAS:DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).Formula:C25H25N3OPurity:98.95%Color and Shape:SolidMolecular weight:383.49Ref: TM-T15080
1mg66.00€5mg145.00€1mL*10mM (DMSO)158.00€10mg236.00€25mg515.00€50mg858.00€100mg1,251.00€200mg1,684.00€Ref: IN-DA003824
250mg23.00€1g25.00€5g57.00€10g78.00€25g138.00€100g500.00€250g831.00€500g1,606.00€1kg3,271.00€Tulmimetostat
CAS:Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advancedFormula:C28H36ClN3O5SPurity:98.04% - 99.87%Color and Shape:SolidMolecular weight:562.12Levetiracetam
CAS:Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onsetFormula:C8H14N2O2Purity:99.67% - 99.86%Color and Shape:SolidMolecular weight:170.215-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purity:99.31% - 99.87%Color and Shape:White SolidMolecular weight:244.2iso-Azalansta
CAS:(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study of cardiovascular disease.Formula:C22H24ClN3O2SPurity:99.45% - 99.89%Color and Shape:SoildMolecular weight:429.96SW2_110A
CAS:SW2_110A: Cell-permeable, CBX8 ChD inhibitor, Kd 800 nM; 5x selective over other CBXs in vitro.Formula:C42H60N6O7Purity:98%Color and Shape:SolidMolecular weight:760.96(-)-Epicatechin gallate
CAS:Formula:C22H18O10Purity:95%Color and Shape:SolidMolecular weight:442.3723Larsucosterol Ammonium salt
CAS:Larsucosterol ammonium salt is a derivative of 25HC3S. It is a DNMT inhibitor, a LXR antagonist, an endogenous epigenetic modulator of lipid metabolism.Formula:C27H49NO5SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:499.75UNC6852
CAS:UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.Formula:C43H48N10O6SPurity:98.69%Color and Shape:SolidMolecular weight:832.97Ref: TM-T13954
1mg126.00€5mg260.00€1mL*10mM (DMSO)358.00€10mg409.00€25mg660.00€50mg888.00€100mg1,224.00€PTD2
PTD2 (Ac-Gly-Val-Nle-Arg-Ile-NH2) serves as a potent and selective WHSC1 inhibitor, exhibiting micromolar affinity for this target [1].Color and Shape:Odour SolidSKLB-03220
CAS:SKLB-03220 is an oral covalent EZH2 inhibitor, abolishing H3K27me3 marks and serving as a potent small-molecule tool for cancer epigenetics research.Formula:C33H40N4O4Purity:97.01%Color and Shape:Yellow SolidMolecular weight:556.71
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