DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
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BCI-121
CAS:432529-82-3
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.
Formula:
C14H18BrN3O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
340.22
Ref: TM-T5322
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
UNC1999
CAS:1431612-23-5
UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 …
Formula:
C33H43N7O2
Purity:
100% - 99.7%
Color and Shape:
Solid
Molecular weight:
569.74
Ref: TM-T3057
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 286.00 € | ||
| 100mg | 515.00 € | ||
| 500mg | 1,130.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
γ-Oryzanol
CAS:11042-64-1
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a …
Formula:
C40H58O4
Purity:
mixture - mixture
Color and Shape:
White Or White Crystalline Powder Odourless
Molecular weight:
602.9
Ref: TM-T3606
| 1g | 52.00 € | ||
| 500mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
PFI-2 hydrochloride
CAS:1627607-87-7
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase …
Formula:
C23H26ClF4N3O3S
Purity:
98.04% - 99.91%
Color and Shape:
Solid
Molecular weight:
535.98
Ref: TM-T4583
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 117.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 552.00 € | ||
| 500mg | 1,169.00 € | ||
| 1mL*10mM (DMSO) | 128.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
EED226
CAS:2083627-02-3
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an …
Formula:
C17H15N5O3S
Purity:
98.14% - 99.66%
Color and Shape:
Solid
Molecular weight:
369.4
Ref: TM-T3458
| 2mg | 40.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK3685032
CAS:2170137-61-6
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).
Formula:
C22H24N6OS
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
420.53
Ref: TM-T9573
| 1mg | 93.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 303.00 € | ||
| 25mg | 567.00 € | ||
| 50mg | 810.00 € | ||
| 100mg | 1,111.00 € | ||
| 1mL*10mM (DMSO) | 200.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Hinokitiol
CAS:499-44-5
Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.
Formula:
C10H12O2
Purity:
99.49% - 99.67%
Color and Shape:
Solid
Molecular weight:
164.2
Ref: TM-T3717
| 1g | 188.00 € | ||
| 50mg | 37.00 € | ||
| 100mg | 62.00 € | ||
| 200mg | 88.00 € | ||
| 500mg | 131.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
2',3',5'-triacetyl-5-Azacytidine
CAS:10302-78-0
2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.
Formula:
C14H18N4O8
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
370.31
Ref: TM-T7840
| 2mg | 40.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 281.00 € | ||
| 200mg | 406.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Zebularine
CAS:3690-10-6
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.
Formula:
C9H12N2O5
Purity:
100% - 99.84%
Color and Shape:
Solid
Molecular weight:
228.2
Ref: TM-T2169
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 283.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
PF-06726304
CAS:1616287-82-1
PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM …
Formula:
C22H21Cl2N3O3
Purity:
98.19% - 98.3%
Color and Shape:
Solid
Molecular weight:
446.33
Ref: TM-T12428L
| 1mg | 39.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 279.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
EPZ015666
CAS:1616391-65-1
EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.
Formula:
C20H25N5O3
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
383.44
Ref: TM-T6076
| 1mg | 49.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 124.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 505.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
EI1
CAS:1418308-27-6
EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM …
Formula:
C23H26N4O2
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
390.48
Ref: TM-T6484
| 5mg | 46.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 240.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Bobcat339
CAS:2280037-51-4
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not …
Formula:
C16H12ClN3O
Purity:
97.79% - 98.76%
Color and Shape:
Solid
Molecular weight:
297.74
Ref: TM-T5198
| 5mg | 51.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 369.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
MM-102 TFA
CAS:1883545-52-5
MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 …
Formula:
C37H50F5N7O6
Purity:
99.3% - 99.4%
Color and Shape:
Solid
Molecular weight:
783.83
Ref: TM-T8768
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 284.00 € | ||
| 50mg | 420.00 € | ||
| 100mg | 620.00 € | ||
| 1mL*10mM (DMSO) | 149.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
XY1
CAS:1624117-53-8
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of …
Formula:
C17H19N3O2
Purity:
97.2% - 97.74%
Color and Shape:
Solid
Molecular weight:
297.35
Ref: TM-T7157
| 5mg | 37.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 101.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 304.00 € | ||
| 200mg | 430.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BAY-598
CAS:1906919-67-2
BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over …
Formula:
C22H20Cl2F2N6O3
Purity:
98.68% - 99.18%
Color and Shape:
Solid
Molecular weight:
525.34
Ref: TM-T7403
| 1mg | 50.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 612.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
CM-272
CAS:1846570-31-7
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
Formula:
C28H38N4O3
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
478.63
Ref: TM-T7194
| 1mg | 73.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 512.00 € | ||
| 50mg | 738.00 € | ||
| 100mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
JQEZ5
CAS:1913252-04-6
JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).
Formula:
C30H38N8O2
Purity:
98.14% - ≥98%
Color and Shape:
Solid
Molecular weight:
542.68
Ref: TM-T7305
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 273.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
CPI-1205
CAS:1621862-70-1
CPI-1205 是一种高效的选择性 EZH2 抑制剂(IC50:0.002 μM,EC50:0.032 μM)。
Formula:
C27H33F3N4O3
Purity:
98.71% - 99.7%
Color and Shape:
Solid
Molecular weight:
518.57
Ref: TM-T8510
| 1mg | 93.00 € | ||
| 2mg | 120.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 743.00 € | ||
| 1mL*10mM (DMSO) | 449.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Lomeguatrib
CAS:192441-08-0
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase …
Formula:
C10H8BrN5OS
Purity:
99.08% - 99.62%
Color and Shape:
Solid
Molecular weight:
326.17
Ref: TM-T2495
| 5mg | 50.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 283.00 € | ||
| 500mg | 705.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
