DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
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MIV-6R
CAS:1560968-55-9
MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.
Formula:
C27H35N3O
Purity:
100.00% - 99.88%
Color and Shape:
Solid
Molecular weight:
417.59
Ref: TM-T24472
| 1mg | 272.00 € | ||
| 5mg | 670.00 € | ||
| 10mg | 916.00 € | ||
| 25mg | 1,437.00 € | ||
| 50mg | 1,872.00 € | ||
| 100mg | 2,561.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Neurodazine
CAS:937807-66-4
Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.
Formula:
C27H21ClN2O3
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
456.92
Ref: TM-T16287
| 2mg | 56.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 267.00 € | ||
| 100mg | 395.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MRK-740
CAS:2387510-80-5
MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.
Formula:
C25H32N6O3
Purity:
99.66%
Color and Shape:
Liquid
Molecular weight:
464.56
Ref: TM-T62957
| 5mg | 102.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 348.00 € | ||
| 50mg | 558.00 € | ||
| 100mg | 822.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(S)-HH2853
CAS:2202678-05-3
(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune …
Formula:
C31H36F3N7O3
Purity:
97.18% - 99.74%
Color and Shape:
Liquid
Molecular weight:
611.66
Ref: TM-T73115
| 1mg | 311.00 € | ||
| 5mg | 747.00 € | ||
| 10mg | 1,059.00 € | ||
| 25mg | 1,579.00 € | ||
| 50mg | 2,127.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-Azacytidine
CAS:320-67-2
Formula:
C8H12N4O5
Purity:
>98.0%(T)
Color and Shape:
White to Almost white powder to crystal
Molecular weight:
244.21
Ref: 3B-A2033
| 1g | 141.00 € | ||
| 100mg | 30.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-Aza-2'-deoxycytidine
CAS:2353-33-5
Formula:
C8H12N4O4
Color and Shape:
White to Almost white powder to crystal
Molecular weight:
228.21
Ref: 3B-A2232
| 20mg | 71.00 € | ||
| 100mg | 213.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SGC2085 HCl
CAS:1821908-49-9
SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.
Formula:
C19H24N2O2·HCl
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
348.87
Ref: TM-T4013
| 1mg | 92.00 € | ||
| 2mg | 147.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 337.00 € | ||
| 25mg | 554.00 € | ||
| 50mg | 807.00 € | ||
| 100mg | 1,112.00 € | ||
| 1mL*10mM (DMSO) | 242.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Piribedil
CAS:3605-01-4
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
Formula:
C16H18N4O2
Purity:
99.83% - 99.91%
Color and Shape:
Solid
Molecular weight:
298.34
Ref: TM-T3278
| 25mg | 62.00 € | ||
| 50mg | 80.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 156.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BCI-121
CAS:432529-82-3
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.
Formula:
C14H18BrN3O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
340.22
Ref: TM-T5322
| 1mg | 35.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 467.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RG108
CAS:48208-26-0
RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).
Formula:
C19H14N2O4
Purity:
98% - 99.78%
Color and Shape:
Solid
Molecular weight:
334.33
Ref: TM-T2038
| 5mg | 46.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 201.00 € | ||
| 100mg | 281.00 € | ||
| 200mg | 393.00 € | ||
| 500mg | 638.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
C-7280948
CAS:587850-67-7
C-7280948 is a PRMT1 inhibitor.
Formula:
C14H16N2O2S
Purity:
98.68% - ≥95%
Color and Shape:
Solid
Molecular weight:
276.35
Ref: TM-T2097
| 5mg | 47.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 186.00 € | ||
| 100mg | 279.00 € | ||
| 200mg | 431.00 € | ||
| 500mg | 690.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
WDR5-0103
CAS:890190-22-4
WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist …
Formula:
C21H25N3O4
Purity:
98% - 99.61%
Color and Shape:
Solid
Molecular weight:
383.44
Ref: TM-T3201
| 5mg | 44.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 315.00 € | ||
| 200mg | 448.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
A-196
CAS:1982372-88-2
A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 …
Formula:
C18H16Cl2N4
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
359.25
Ref: TM-T4343
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 340.00 € | ||
| 100mg | 516.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNC0646
CAS:1320288-17-2
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and …
Formula:
C36H59N7O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
621.9
Ref: TM-TQ0232
| 5mg | 63.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 179.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZ505
CAS:1035227-43-0
AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).
Formula:
C29H38Cl2N4O4
Purity:
98.18%
Color and Shape:
Solid
Molecular weight:
577.54
Ref: TM-TQ0100
| 1mg | 63.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 644.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tazemetostat hydrobromide
CAS:1467052-75-0
Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: …
Formula:
C34H45BrN4O4
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
653.65
Ref: TM-T17002
| 2mg | 42.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 80.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 157.00 € | ||
| 200mg | 227.00 € | ||
| 500mg | 369.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SGC0946
CAS:1561178-17-3
SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill …
Formula:
C28H40BrN7O4
Purity:
98% - 99.82%
Color and Shape:
Solid
Molecular weight:
618.57
Ref: TM-T3082
| 2mg | 53.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 423.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TC-E 5003
CAS:17328-16-4
TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.
Formula:
C16H14Cl2N2O4S
Purity:
97.01%
Color and Shape:
Solid
Molecular weight:
401.26
Ref: TM-T21826
| 25mg | 46.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 138.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Gambogenic acid
CAS:173932-75-7
Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.
Formula:
C38H46O8
Purity:
98.36% - 99.6%
Color and Shape:
Solid
Molecular weight:
630.77
Ref: TM-T8201
| 1mg | 91.00 € | ||
| 5mg | 204.00 € | ||
| 10mg | 353.00 € | ||
| 25mg | 582.00 € | ||
| 50mg | 820.00 € | ||
| 100mg | 1,095.00 € | ||
| 1mL*10mM (DMSO) | 281.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNC3866
CAS:1872382-47-2
UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.
Formula:
C43H66N6O8
Purity:
88.06% - 99.47%
Color and Shape:
Solid
Molecular weight:
795.02
Ref: TM-T4021
| 1mg | 52.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 317.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 715.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
