Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(207 products)
- Annexin A(11 products)
- Aromatase(20 products)
- Estrogen/progestogen Receptor(49 products)
- GPR(1 products)
- Glucocorticoid Receptor(153 products)
- LHRH(1 products)
- Opioid Receptor(296 products)
- Prostaglandin Receptor(119 products)
- RAAS(86 products)
- Reductase(52 products)
- Somatostatin(46 products)
- Thyroid hormone receptor(THR)(26 products)
- Vasopressin Receptor(44 products)
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Found 3178 products of "Endocrinology/Hormones"
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PROTAC ER Degrader-4
CAS:<p>PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).</p>Formula:C53H67F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:1005.2Nurr1 agonist 2
CAS:<p>Nurr1 agonist 2 with EC50 of 0.07 μM, boosts TH & VMAT2 mRNA, binds Nurr1 LBD at Kd 0.14 μM, for parkinsonism study.</p>Formula:C18H14O3SPurity:98.78%Color and Shape:SoildMolecular weight:310.37Cebranopadol hemicitrate
CAS:<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Color and Shape:SolidBufrolin
CAS:<p>Bufrolin is a potent GPR35 agonist, mast cell stabilizer, and anti-inflammatory research agent.</p>Formula:C18H16N2O6Color and Shape:SolidMolecular weight:356.33PD 125967
CAS:<p>PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.</p>Formula:C51H67N5O4Color and Shape:SolidMolecular weight:814.11CTAP
CAS:<p>Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.</p>Formula:C51H69N13O11S2Purity:98%Color and Shape:White Solid/PowderMolecular weight:1104.32Ac-RYYRIK-NH2
CAS:<p>NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.</p>Formula:C44H70N14O9Purity:98%Color and Shape:SolidMolecular weight:939.12SL910102
CAS:<p>SL910102 is a nonpeptide angiotensin antagonist of the AT1 receptor.</p>Formula:C30H30N6OPurity:98%Color and Shape:SolidMolecular weight:490.60Neuropeptide AF (human)
CAS:<p>Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.</p>Formula:C90H132N26O25Purity:98%Color and Shape:SolidMolecular weight:1978.17Angiotensin amide
CAS:<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Formula:C49H70N14O11Purity:98%Color and Shape:SolidMolecular weight:1031.17Dynorphin B (1-13)
CAS:<p>Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.</p>Formula:C74H115N21O17Purity:98%Color and Shape:SolidMolecular weight:1570.843-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Color and Shape:Odour SolidGNE-502
CAS:<p>GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.</p>Formula:C25H30FN3O3SColor and Shape:SolidMolecular weight:471.59Remikiren
CAS:<p>Remikiren is a highly specific renin inhibitor with oral activity for the treatment of hypertensio.</p>Formula:C33H50N4O6SColor and Shape:SolidMolecular weight:630.842-Ethylhexyl trans-4-methoxycinnamate
CAS:<p>2-Ethylhexyl trans-4-methoxycinnamate is a sunscreen agent.</p>Formula:C18H26O3Purity:98.92%Color and Shape:Pale Yellow LiquidMolecular weight:290.41α-Hydroxy-3-epi-vitamin D3
CAS:<p>1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].</p>Formula:C27H44O2Color and Shape:SolidMolecular weight:400.6474'-hydroxy Tamoxifen
CAS:<p>It is a metabolite of tamoxifen and an estrogen receptor modulator.</p>Formula:C26H29NO2Purity:98%Color and Shape:SolidMolecular weight:387.51Antihypertensive agent 3
<p>Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs</p>Formula:C16H13NO4SColor and Shape:SolidMolecular weight:315.34Perindoprilat
CAS:<p>Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.</p>Formula:C17H28N2O5Purity:99.48%Color and Shape:SolidMolecular weight:340.41Biphalin TFA
CAS:<p>Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.</p>Formula:C46H56N10O10·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:909.00 (free base)Antitumor agent-195
<p>Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.</p>Formula:C22H22N2O4Color and Shape:SolidMolecular weight:378.42Antihypertensive agent 2
<p>Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or</p>Formula:C22H15NO3Color and Shape:SolidMolecular weight:341.36Betamethasone acibutate
CAS:<p>Betamethasone acibutate, a glucocorticoid, is derived from Betamethasone.</p>Formula:C28H37FO7Purity:98%Color and Shape:SolidMolecular weight:504.59Methylpiperidino pyrazole
CAS:<p>Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression.</p>Formula:C29H31N3O3Purity:98.84%Color and Shape:SolidMolecular weight:469.57OT-R antagonist 2
CAS:<p>OT-R antagonist 2 is a nonpeptide low molecular weight antagonist of OT-R .</p>Formula:C28H29N3O4Purity:98%Color and Shape:SolidMolecular weight:471.55DAMGO (TFA)
CAS:<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Formula:C28H36F3N5O8Purity:98%Color and Shape:SolidMolecular weight:627.61ARD-2585
CAS:<p>ARD-2585 is an orally active and selective androgen receptor PROTAC degrader with anticancer activity for the study of prostate cancer.</p>Formula:C41H43ClN8O5Color and Shape:SolidMolecular weight:763.283-epi-25-hydroxy Vitamin D3
CAS:<p>3-epi-25-hydroxy Vitamin D3 lowers serum PTH in male weanling rats at 0.5 and 1 IU/g doses; doesn't affect females.</p>Formula:C27H44O2Color and Shape:SolidMolecular weight:400.64GNE-274
CAS:<p>GNE-274, akin to GDC-0927 but non-degrading, is a partial ER agonist in breast cancer, enhancing chromatin at ER sites, inhibiting ER-LBD.</p>Formula:C29H31NO4Color and Shape:SolidMolecular weight:457.57Alclometasone
CAS:<p>Alclometasone is a glucocorticoid that reduces inflammation and treats various skin conditions like eczema and psoriasis.</p>Formula:C22H29ClO5Purity:98%Color and Shape:SolidMolecular weight:408.92Axelopran
CAS:<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Formula:C26H39N3O4Color and Shape:SolidMolecular weight:457.61Methylprednisolone Acetate
<p>Methylprednisolone Acetate(Depo-Medrate) has the ability to inhibit oxygen free radicals and can be used to treat acute spinal cord injuries.</p>Formula:C24H32O6Purity:99.74%Color and Shape:Off-White SolidMolecular weight:416.51D3R/MOR antagonist 2
<p>Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MOR</p>Formula:C25H31ClN2OPurity:98%Color and Shape:SolidMolecular weight:410.98PTP1B/AKR1B1-IN-1
<p>PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s</p>Formula:C22H21NO4S2Purity:98%Color and Shape:SolidMolecular weight:427.54Dipropyl phthalate
CAS:<p>Dipropyl phthalate is a weak androgen receptor inhibitor, and can be used in biochemical experiments and drug synthesis.</p>Formula:C14H18O4Purity:98.62%Color and Shape:SolidMolecular weight:250.29ARCC-4
CAS:<p>ARCC-4: A VHL-recruiting, low-nanomolar (DC50=5nM) AR degrader; outshines enzalutamide; degrades AR mutants resistant to therapy.</p>Formula:C53H56F3N7O7S2Purity:98%Color and Shape:SolidMolecular weight:1024.18BigLEN(mouse)
CAS:<p>GPR171 agonist from ProSAAS controls mouse appetite, reduces glutamate in paraventricular neurons via G protein.</p>Formula:C78H130N24O22Purity:98%Color and Shape:SolidMolecular weight:1756.03PROTAC ERRα Degrader-2
CAS:<p>PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group.</p>Formula:C57H55Cl2F6N7O8Purity:98%Color and Shape:SolidMolecular weight:1150.99Parathyroid hormone (1-34) (rat)
CAS:<p>Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.</p>Formula:C180H291N55O48S2Purity:98%Color and Shape:SolidMolecular weight:4057.74BWA-6047
<p>BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.</p>Formula:C42H46ClN5O7Color and Shape:SolidMolecular weight:767.30858Glucocorticoids receptor agonist 1
CAS:<p>GRA-1, an arylpyrazole, is a potent glucocorticoid receptor agonist with robust anti-inflammatory effects and preserves insulin secretion.</p>Formula:C20H23FN2OColor and Shape:SolidMolecular weight:326.41Akuammicine
CAS:<p>Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.</p>Formula:C20H22N2O2Color and Shape:SolidMolecular weight:322.408Alunacedase alfa
CAS:<p>Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.</p>Purity:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Color and Shape:Liquid4A7C-301
<p>4A7C-301, a Nurr1 agonist, exhibits potent neuroprotective effects in vitro and markedly mitigates neuropathological abnormalities while enhancing motor and</p>Color and Shape:Odour SolidMontirelin
CAS:<p>Montirelin is an analog of thyrotropin-releasing hormone.</p>Formula:C17H24N6O4SColor and Shape:SolidMolecular weight:408.48(Rac)-Finerenone
CAS:<p>Rac-Finerenone, or (Rac)-BAY 94-8862, is an oral nonsteroidal MR antagonist with high selectivity and an IC50 of 18 nM.</p>Formula:C21H22N4O3Color and Shape:SolidMolecular weight:378.432[Orn5]-URP
CAS:<p>Urotensin-II receptor antagonist, no agonist effect, pEC50 7.24, blocks U-II in rat aorta assay.</p>Formula:C48H62N10O10S2Purity:98%Color and Shape:SolidMolecular weight:1003.2Dermorphin Analog
<p>Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.</p>Formula:C44H59N11O10Purity:98%Color and Shape:SolidMolecular weight:901.43ZINC05925939
<p>ZINC05925939 is an estrogen receptor β (ESR2) inhibitor used in breast cancer research.</p>Formula:C17H17NO2Color and Shape:SolidMolecular weight:267.32PROTAC ER Degrader-3
CAS:<p>PROTAC ER Degrader-3 from patent WO2017201449A1 is a PAC synthesis intermediate for ADC/PROTAC antibody conjugates, boosting ERα degradation.</p>Formula:C71H77N7O12Purity:98%Color and Shape:SolidMolecular weight:1220.434
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