Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(207 products)
- Annexin A(11 products)
- Aromatase(20 products)
- Estrogen/progestogen Receptor(49 products)
- GPR(1 products)
- Glucocorticoid Receptor(153 products)
- LHRH(1 products)
- Opioid Receptor(296 products)
- Prostaglandin Receptor(119 products)
- RAAS(86 products)
- Reductase(52 products)
- Somatostatin(46 products)
- Thyroid hormone receptor(THR)(26 products)
- Vasopressin Receptor(44 products)
Show 6 more subcategories
Found 3178 products of "Endocrinology/Hormones"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BMS-986034
CAS:<p>BMS-986034 is a GPR119 agonist.</p>Formula:C24H24Cl2N6O4Color and Shape:SolidMolecular weight:531.39TD-0212 TFA
CAS:<p>TD-0212 TFA is an oral AT1 receptor antagonist & NEP inhibitor with pKi 8.9 & pIC50 9.2.</p>Formula:C30H35F4N3O6SPurity:98%Color and Shape:SolidMolecular weight:641.67L 365209
CAS:<p>L 365209 is an oxytocin antagonist.</p>Formula:C40H50N8O6Purity:98%Color and Shape:SolidMolecular weight:738.88SB-612111
CAS:<p>SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.</p>Formula:C24H29Cl2NOColor and Shape:SolidMolecular weight:418.40Mu opioid receptor antagonist 3
<p>Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.</p>Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57Mu opioid receptor antagonist 2
<p>Compound 25: potent, selective MOR antagonist, crosses blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), for OUD research.</p>Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57BW 443C
CAS:<p>BW 443C is a selective agonist of mu-opioid receptor.</p>Formula:C33H46N10O10Color and Shape:SolidMolecular weight:742.791CI 992
CAS:<p>CI 992 is a novel potent inhibitor of primate renin.</p>Formula:C33H52N6O7S2Color and Shape:SolidMolecular weight:708.93TUG-2181
CAS:<p>TUG-2181 is an antagonist of GPR84, with an IC50 value of 34 nM. It inhibits reactive oxygen species (ROS) production and IL-8 secretion induced by GPR84 agonists in human neutrophils. TUG-2181 is applicable for research in inflammation and fibrosis.</p>Formula:C21H27NO4Color and Shape:SolidMolecular weight:357.443AT1R antagonist 2
<p>AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).</p>Formula:C29H37N5O4S2Color and Shape:SolidMolecular weight:583.77S-HP210
<p>S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.</p>Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54Daeatal
CAS:<p>Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.</p>Formula:C56H93N19O10Purity:98%Color and Shape:SolidMolecular weight:1192.46MLS000389544
CAS:<p>MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).</p>Formula:C20H24N2O7SColor and Shape:SolidMolecular weight:436.479RX 809055AX
CAS:<p>RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.</p>Formula:C29H29ClN2O4Color and Shape:SolidMolecular weight:505SB-612111 hydrochloride
<p>SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.</p>Formula:C24H30Cl3NOColor and Shape:SolidMolecular weight:454.8621-Deacetoxy deflazacort
CAS:<p>21-Deacetoxy deflazacort is a dehydrogenated derivative of Deflazacort, which is a glucocorticoid. As an inactive precursor, Deflazacort rapidly converts into the active metabolite, 21-Desacetyldeflazacort. This compound serves as both an anti-inflammatory and immunosuppressive agent.</p>Formula:C23H29NO4Color and Shape:SolidMolecular weight:383.48GNTI dihydrochloride
CAS:<p>κ opioid receptor antagonist</p>Formula:C27H30ClN5O3Purity:98%Color and Shape:SolidMolecular weight:508.01A4B17
<p>A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.</p>Formula:C14H7F4NSColor and Shape:SolidMolecular weight:297.27DS69910557
<p>DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.</p>Formula:C32H33Cl2FN4O3Color and Shape:SolidMolecular weight:611.53BNTX maleate
CAS:<p>δ1 opioid receptor antagonist</p>Formula:C31H31NO8Purity:98%Color and Shape:SolidMolecular weight:545.58ACT 178882
CAS:<p>ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).</p>Formula:C33H38Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:647.03Androgen receptor antagonist 11
CAS:<p>Androgen receptor antagonist 11 (compound N29) is a selective, orally available antagonist.</p>Formula:C20H19F3N4O3SColor and Shape:SolidMolecular weight:452.45J-113397
CAS:<p>J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).</p>Formula:C24H37N3O2Purity:98%Color and Shape:SolidMolecular weight:399.57ER degrader 10
CAS:<p>ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 μM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.</p>Formula:C28H29F2NO3SColor and Shape:SolidMolecular weight:497.597ADX61623
CAS:<p>ADX61623 is an effective negative allosteric modulator (NAM) of the follicle-stimulating hormone receptor (FSHR). It also exhibits activity on the luteinizing hormone receptor (LH-R) but is inactive on the thyroid-stimulating hormone (TSH) receptor. ADX61623 can be utilized in research on estrogen-dependent diseases.</p>Formula:C19H20N2O3Color and Shape:SolidMolecular weight:324.37ERα degrader 11
CAS:<p>ERα degrader11 (compound B16) is a selective estrogen receptor degrader designed for use as a probe in examining the ER status within ER-positive breast cancer cells.</p>Formula:C28H27F3N2O3Color and Shape:SolidMolecular weight:496.52Fonsartan free acid
CAS:<p>Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.</p>Formula:C26H32N4O5S2Purity:98%Color and Shape:SolidMolecular weight:544.69Pentomone
CAS:<p>Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.</p>Formula:C24H26O5Color and Shape:SolidMolecular weight:394.46Sob-AM2
CAS:<p>Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).</p>Formula:C21H27NO3Color and Shape:SolidMolecular weight:341.44(S)-MCOPPB
CAS:<p>(S)-MCOPPB is the S-enantiomer of MCOPPB, an orally active selective agonist for the Nociceptin/Orphanin FQ-Receptor. It inhibits signal transduction in mouse brain NOP receptors and is utilized in anxiety disorder research.</p>Formula:C26H40N4Color and Shape:SolidMolecular weight:408.623L162389
CAS:<p>L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.</p>Formula:C31H38N4O4SPurity:99.11% - 99.57%Color and Shape:SolidMolecular weight:562.72Androgen receptor ligand 1
CAS:<p>Androgen receptorligand 1 is a ligand for the androgen receptor (AR). It interacts with the CRBN E3 ligase via a linker to form an AR-PROTAC degrader. This compound is useful in prostate cancer research.</p>Formula:C19H16F4N2OColor and Shape:SolidMolecular weight:364.34OT-R agonist 1 TFA
CAS:<p>OT-R agonist 1 TFA (compound 5) is an oxytocin receptor (OT-R) agonist with an EC50 value of 0.39 nM. It exhibits V1A antagonist activity, with an EC50 value of 2432 nM, and can be utilized in studies related to central nervous system diseases.</p>Formula:C37H40F3N7O7SColor and Shape:SolidMolecular weight:783.82Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Formula:C16H20N2O5Color and Shape:SolidMolecular weight:320.34NSC 645827
CAS:<p>NSC 645827 is an inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), with an IC50 of 0.7 μM.</p>Formula:C17H17N5O2Color and Shape:SolidMolecular weight:323.349AR antagonist 4
<p>AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).</p>Formula:C29H36N4OColor and Shape:SolidMolecular weight:456.62ERα degrader 5
<p>ERα degrader 5 is an orally active, selective estrogen receptor (ER) reducer that acts on ERα (EC50: 1.1 nM). ERα degrader 5 shows anti-tumour effects in vivo.</p>Formula:C29H25F4N3O2SColor and Shape:SolidMolecular weight:555.595α-reductase-IN-1
CAS:<p>5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.</p>Formula:C31H37NO5Purity:98%Color and Shape:SolidMolecular weight:503.63BU09059
CAS:<p>BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).</p>Formula:C28H37N3O5Purity:98%Color and Shape:SolidMolecular weight:495.61Anticancer agent 257
CAS:<p>Anticanceragent 257 (compound of formula (I)) is an anticancer agent that regulates Nur77 and Nurr1.</p>Formula:C15H9Cl2N3Color and Shape:SolidMolecular weight:302.158JTP-117968
CAS:<p>JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.</p>Formula:C31H31F3N2O2Color and Shape:SolidMolecular weight:520.59MB-07344 sodium
<p>"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."</p>Formula:C19H25NaO5PPurity:98%Color and Shape:SolidMolecular weight:387.36Mepixetil
<p>Mepixetil is a potent angiotensin II receptor antagonist[1].</p>Formula:C12H18N2O3Color and Shape:SolidMolecular weight:238.28Mopivabil
<p>Mopivabil is the angiotensin II receptor antagonist[1].</p>Formula:C14H20O3Color and Shape:SolidMolecular weight:236.31GPR84 antagonist 1
<p>GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.</p>Formula:C26H22N4O2Color and Shape:SolidMolecular weight:422.48Mu opioid receptor antagonist 5
<p>Compound NAP: MOR antagonist, crosses blood-brain barrier, EC50: 1.14 nM, Ki: 0.37 nM, useful for OUD research.</p>Formula:C26H29N3O4Color and Shape:SolidMolecular weight:447.53ZD 7155 hydrochloride
CAS:<p>ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.</p>Formula:C26H27ClN6OPurity:99.8%Color and Shape:SolidMolecular weight:474.98GLPG0974
CAS:<p>GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.</p>Formula:C25H25ClN2O4SPurity:99.8%Color and Shape:SolidMolecular weight:484.99Cort108297
CAS:<p>Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.</p>Formula:C26H25F4N3O3SPurity:98.36% - 99.94%Color and Shape:SolidMolecular weight:535.55Nalmefene
CAS:<p>Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used in the study of opioid overdose and alcohol dependence.</p>Formula:C21H25NO3Purity:99.86%Color and Shape:SolidMolecular weight:339.43
