Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(23 products)
- Estrogen/progestogen Receptor(66 products)
- GPR(1 products)
- Glucocorticoid Receptor(165 products)
- LHRH(2 products)
- Opioid Receptor(327 products)
- Prostaglandin Receptor(122 products)
- RAAS(89 products)
- Reductase(51 products)
- Somatostatin(57 products)
- Thyroid hormone receptor(THR)(33 products)
- Vasopressin Receptor(48 products)
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Found 3420 products of "Endocrinology/Hormones"
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LY2066948
CAS:LY2066948 is a selective oral estrogen receptor modulator (SERM) with high affinity for estrogen receptors ERα and ERβ (Ki of 0.51 and 1.36 nM, respectively) and displays potent anti-estrogenic activity. It effectively blocks the increase in uterine weight induced by ethinylestradiol in immature rats. LY2066948 is utilized in the research of uterine fibroids and myomas.Formula:C30H31NO5SColor and Shape:SolidMolecular weight:517.64A 74273
CAS:A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Formula:C44H74N4O8Purity:98%Color and Shape:SolidMolecular weight:787.08Daeatal
CAS:Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.Formula:C56H93N19O10Purity:98%Color and Shape:SolidMolecular weight:1192.46(+)-JJ-74-138
CAS:(+)-JJ-74-138 is a novel non-competitive androgen receptor (AR) antagonist capable of inhibiting enzalutamide-resistant castration-resistant prostate cancer (CRPC).Formula:C22H22F8N2OSColor and Shape:SolidMolecular weight:514.48Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formula:C30H40Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:531.56MK-6913
CAS:MK-6913 is a potent and selective agonist of estrogen receptor β.Formula:C25H27N3O2Purity:98%Color and Shape:SolidMolecular weight:401.5Isotodesnitazene
CAS:Isotodesnitazene is an opioid compound that primarily targets the μ-opioid receptor (MOR). It exhibits EC50 values of 34.8 nM and 142 nM for MOR-βarr2 and MOR-mini-Gi, respectively. Isotodesnitazene can be utilized for research in opioid drugs.Formula:C23H31N3OColor and Shape:SolidMolecular weight:365.51CCG258747
CAS:CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Formula:C28H27FN4O4Color and Shape:SolidMolecular weight:502.54Salvinorin A Propionate
CAS:Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.Formula:C24H30O8Color and Shape:SolidMolecular weight:446.49Sunobinop
CAS:Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.Formula:C26H33N3O3Color and Shape:SolidMolecular weight:435.56Naldemedine tosylate
CAS:Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.Formula:C39H42N4O9SColor and Shape:SolidMolecular weight:742.84Anilopam
CAS:Anilopam is an opioid analgesic belonging to the benzazepine class and acts as an agonist at opioid receptors.Formula:C20H26N2OColor and Shape:SolidMolecular weight:310.43GPR84 antagonist 3
CAS:Potent GPR84 antagonist 3 (compound 42), pIC50 8.28, inhibits GTPγS, with good pharmacokinetics.Formula:C29H27N5OColor and Shape:SolidMolecular weight:461.56Androgen receptor antagonist 12
CAS:Compound EF2 (Androgen receptor antagonist 12) is an orally active antagonist of the androgen receptor (AR) with an IC50 of 0.30 µM. It inhibits the transcriptional activity of mutant AR and the proliferation of AR-positive PCa (prostate cancer) cell lines. Additionally, Compound EF2 blocks the nuclear translocation of AR and suppresses tumor growth in the C4-2B xenograft mouse model. This compound is used for research in prostate cancer.Formula:C12H8F3N3O2Color and Shape:SolidMolecular weight:283.2122-Thiocyanatosalvinorin A
CAS:22-Thiocyanatosalvinorin A (RB-64) is a potent selective agonist for the kappa-opioid receptor, exhibiting an EC50 value of 0.077 nM.Formula:C24H27NO8SColor and Shape:SolidMolecular weight:489.54JNJ-1250132
CAS:JNJ-1250132 is a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro.Formula:C33H41NO4Color and Shape:SolidMolecular weight:515.68L 365209
CAS:L 365209 is an oxytocin antagonist.Formula:C40H50N8O6Purity:98%Color and Shape:SolidMolecular weight:738.88Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57BNTX maleate
CAS:δ1 opioid receptor antagonistFormula:C31H31NO8Purity:98%Color and Shape:SolidMolecular weight:545.58rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFormula:C24H30Cl3NOPurity:98%Color and Shape:SolidMolecular weight:454.86TRβ agonist 1
CAS:TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.Formula:C29H25FN2O8Color and Shape:SolidMolecular weight:548.52ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research.Formula:C17H21N5OColor and Shape:SolidMolecular weight:311.38Estrogen receptor-agonist-1
CAS:Estrogen receptor-agonist-1 (compound 4e) is an estrogen receptor (ER) agonist that binds to ERα with high affinity.Formula:C24H22N2O2Color and Shape:SolidMolecular weight:370.444SDM25N hydrochloride
CAS:δ receptor antagonistFormula:C26H27ClN2O3Purity:98%Color and Shape:SolidMolecular weight:450.96Fonsartan free acid
CAS:Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Formula:C26H32N4O5S2Purity:98%Color and Shape:SolidMolecular weight:544.695α-Tetrahydrocorticosterone
CAS:5α-Tetrahydrocorticosterone (5α-HB) is an endogenous steroid that acts as an agonist of the glucocorticoid receptor (GR) and a metabolite of corticosterone. It serves as an effective topical anti-inflammatory agent in vivo. In rat liver cells, it decreases the binding of metabolites to the glucocorticoid receptor-corticosterone and its 5α-reduced metabolites, with a Kd value of 268 nM. 5α-Tetrahydrocorticosterone is applicable in research on inflammatory skin diseases.Formula:C21H34O4Color and Shape:SolidMolecular weight:350.49AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Formula:C29H37N5O4S2Color and Shape:SolidMolecular weight:583.77Cort108297
CAS:Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.Formula:C26H25F4N3O3SPurity:98.36% - 99.94%Color and Shape:SolidMolecular weight:535.55Ref: TM-T15000
1mg260.00€5mg590.00€10mg859.00€25mg1,341.00€50mg1,783.00€100mg2,602.00€1mL*10mM (DMSO)708.00€ZD 7155 hydrochloride
CAS:ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Formula:C26H27ClN6OPurity:99.8%Color and Shape:SolidMolecular weight:474.98Ref: TM-T13390
1mg42.00€5mg88.00€10mg135.00€25mg235.00€50mg396.00€100mg635.00€200mg887.00€1mL*10mM (DMSO)90.00€GLPG0974
CAS:GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.Formula:C25H25ClN2O4SPurity:99.8%Color and Shape:SolidMolecular weight:484.99L-371,257
CAS:L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.Formula:C28H33N3O6Purity:99.79%Color and Shape:SolidMolecular weight:507.58(E/Z)-GSK5182
CAS:GSK5182 is a racemic mix of (E/Z) isomers, a selective ERRγ inverse agonist (IC50: 79 nM), and induces ROS in liver cancer.Formula:C27H31NO3Purity:97.58%Color and Shape:SolidMolecular weight:417.54Ref: TM-T7709
1mg77.00€5mg167.00€10mg260.00€25mg477.00€50mg707.00€100mg1,063.00€1mL*10mM (DMSO)177.00€LSZ-102
CAS:LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.Formula:C25H17F3O4SPurity:98.56%Color and Shape:SolidMolecular weight:470.46Mapracorat
CAS:Mapracorat (ZK-245186, BOL-303242X) is a selective glucocorticoid receptor agonist,anti-inflammatory agent for atopic dermatitis and allergic conjunctivitis.Formula:C25H26F4N2O2Color and Shape:SolidMolecular weight:462.48PSN632408
CAS:PSN632408 is an optimized agonist of GPR119 receptors that display similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50: 5.6 and 7.9 uM, respectively).Formula:C18H24N4O4Purity:98%Color and Shape:SolidMolecular weight:360.41ML314
CAS:ML314 is a brain-permeable nonpeptide β-inhibin-biased neurotensin NTR1 receptor agonist (EC50: 1.9 μM), a biased neurotensin receptor ligand for methamphetamine abuse that inhibits NTR2 and GPR35.Formula:C24H28N4O3Purity:99.52%Color and Shape:SolidMolecular weight:420.504(S)-Mapracorat
CAS:(S)-Mapracorat is a selective and less active agonist of the glucocorticoid receptor.Formula:C25H26F4N2O2Color and Shape:SolidMolecular weight:462.48Mouse MDA(Malondialdehyde) ELISA Kit
This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse MDA protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse MDA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse MDA in the samples is then determined by comparing the OD of the samples to the standard curve.
Relacorilant
CAS:Relacorilant is an oral glucocorticoid receptor antagonist with Ki of 7.2 nM, potential for treating Cushing's syndrome.
Formula:C27H22F4N6O3SPurity:98.53% - 99%Color and Shape:SolidMolecular weight:586.56Horse IGF1(Insulin Like Growth Factor 1) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Horse IGF1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Horse IGF1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Horse IGF1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Horse IGF1 in the samples is then determined by comparing the OD of the samples to the standard curve.
Rat VLDL(Very Low Density Lipoprotein) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat VLDL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat VLDL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat VLDL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat VLDL in the samples is then determined by comparing the OD of the samples to the standard curve.
Omzotirome
CAS:Omzotirome (TRC150094) is a functional analog of iodothyronines and holds potential for research on hyperlipidemia (WO2008149379).Formula:C19H24N2O3Color and Shape:SolidMolecular weight:328.412L-372662
CAS:L-372662 is bioactive chemical.Formula:C33H38N4O6Color and Shape:SolidMolecular weight:586.68ERB-196
CAS:Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.Formula:C17H10FNO2Purity:98%Color and Shape:SolidMolecular weight:279.27AZD9496 maleate
CAS:AZD9496 maleate is a highly potent and selective antagonist of the estrogen receptor alpha (ERα), exhibiting an IC50 value of 0.28 nM. This compound, AZD9496 maleate, is an orally bioavailable selective estrogen receptor degrader (SERD).Formula:C29H29F3N2O6Color and Shape:SolidMolecular weight:558.55421-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is a valuable organic compound for life sciences research [Catalog No.: T67476, CAS No.: 37413-91-5].Formula:C23H26O4Color and Shape:SolidMolecular weight:366.457PF-998425
CAS:non-steroidal androgen receptor (AR) antagonistFormula:C14H14F3NOPurity:98%Color and Shape:SolidMolecular weight:269.26Phosphoramidon Disodium
CAS:Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.Formula:C23H34N3Na2O10PPurity:98%Color and Shape:SolidMolecular weight:588.48GPR109 receptor agonist-2
CAS:Compound 5, a selective GPR109a agonist, exhibits a pEC50 value of 5.53 [1].Formula:C7H10N2O2Color and Shape:SolidMolecular weight:154.17Pamoic acid
CAS:Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Formula:C23H16O6Purity:99.99%Color and Shape:Fine Yellow PowderMolecular weight:388.37
