Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(22 products)
- Estrogen/progestogen Receptor(55 products)
- GPR(1 products)
- Glucocorticoid Receptor(167 products)
- LHRH(1 products)
- Opioid Receptor(322 products)
- Prostaglandin Receptor(122 products)
- RAAS(90 products)
- Reductase(50 products)
- Somatostatin(54 products)
- Thyroid hormone receptor(THR)(30 products)
- Vasopressin Receptor(46 products)
Show 6 more subcategories
Found 3359 products of "Endocrinology/Hormones"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
OSU-ERb-12
CAS:OSU-ERb-12 is an ERβ agonist that suppresses ovarian cancer cell proliferation both in vitro and in vivo, and decreases the expression of Snail [1] [2].Formula:C15H30B10O2Color and Shape:SolidMolecular weight:350.51BU72
CAS:<p>BU72 is a potent, long-lasting agonist for μ and κ opioid receptors, with partial agonistic activity at the δ opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively). It provides strong, enduring analgesic effects primarily mediated through μ opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.</p>Formula:C28H32N2O2Color and Shape:SolidMolecular weight:428.57LX1
CAS:LX1, an anti-prostate cancer compound, specifically targets the androgen receptor (AR), AR variants, and the steroidogenic enzyme AKR1C3. It inhibits AKR1C3's enzymatic function, decreases the conversion of androstenedione to testosterone, and reduces the expression of both AR and AR-V7, subsequently downregulating their target genes. Additionally, LX1 is effective in overcoming tumor cell resistance to Enzalutamide, and when combined with Enzalutamide, it further suppresses tumor growth.Formula:C22H15F6NO2Color and Shape:SolidMolecular weight:439.35Androgen receptor degrader-5
CAS:Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.Formula:C29H25F4N5O2Color and Shape:SolidMolecular weight:551.53Amoitone B
CAS:Amoitone B, a cystosporone B derivative, functions as an NR4A1 agonist and exhibits anticancer activity [1].Formula:C22H34O5Color and Shape:SolidMolecular weight:378.5(Rac)-Fidarestat
CAS:(Rac)-Fidarestat ((Rac)-SNK 860) is the racemic form of Fidarestat, functioning as a potent inhibitor of the enzyme aldose reductase.Formula:C12H10FN3O4Color and Shape:SolidMolecular weight:279.224Riminkefon
CAS:Riminkefon is a kappa opioid receptor agonist .Formula:C38H57N7O6Color and Shape:SolidMolecular weight:707.9Mu opioid receptor antagonist 8
CAS:<p>Muopioid Receptor Antagonist 8 (368) serves as an antagonist to the μ-opioid receptor, significantly inhibiting the activation of Gi induced by met-enkephalin at the µOR.</p>Formula:C36H35N3O4SColor and Shape:SolidMolecular weight:605.756β-Naltrexol
CAS:6β-Naltrexol is a peripherally selective opioid antagonist that reduces constipation from opioids while minimizing central nervous system effects.Formula:C20H25NO4Purity:99.933%Color and Shape:SolidMolecular weight:343.42KR31173
CAS:KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET). In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.Formula:C31H30N8O2Color and Shape:SolidMolecular weight:546.62DS34942424
DS34942424 is an orally potent analgesic which did not exhibit mu opioid receptor agonist activity.Formula:C15H17FN2OColor and Shape:SolidMolecular weight:260.31FL442
CAS:FL442 is an Androgen Receptor (AR) modulator. This compound exhibits potent inhibitory effects in AR-dependent prostate cancer cells, showing similar suppression efficiency to the traditional antiandrogen drugs Bicalutamide and Enzalutamide. It also maintains antiandrogen activity against the Enzalutamide-resistant AR mutant F876L. The pharmacokinetic properties of FL442 in mice reveal a longer half-life (8 hours), excellent targeting (prostate tissue), and metabolic stability. Additionally, it is effective at inhibiting LNCaP tumor growth at low plasma concentrations (30 ng/mL).Formula:C15H13F3N2OColor and Shape:SolidMolecular weight:294.27Opioid receptor antagonist 1
CAS:<p>Opioid receptor antagonist 1 (Compound 10) is an Orvinol-based antagonist of opioid receptors. It exhibits activity as an antagonist against the analgesic properties of morphine.</p>Formula:C24H29ClF3NO4Color and Shape:SolidMolecular weight:487.94Mu opioid receptor antagonist 5
Compound NAP: MOR antagonist, crosses blood-brain barrier, EC50: 1.14 nM, Ki: 0.37 nM, useful for OUD research.Formula:C26H29N3O4Color and Shape:SolidMolecular weight:447.53Galaxolide
CAS:Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), oxidative stress, and genotoxicity. It also stimulates the enzymatic activities of EROD and GST (Glutathione S-transferase).Formula:C18H26OColor and Shape:SolidMolecular weight:258.40GPR84 antagonist 1
GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.Formula:C26H22N4O2Color and Shape:SolidMolecular weight:422.48Isotodesnitazene
CAS:Isotodesnitazene is an opioid compound that primarily targets the μ-opioid receptor (MOR). It exhibits EC50 values of 34.8 nM and 142 nM for MOR-βarr2 and MOR-mini-Gi, respectively. Isotodesnitazene can be utilized for research in opioid drugs.Formula:C23H31N3OColor and Shape:SolidMolecular weight:365.51Mopivabil
Mopivabil is the angiotensin II receptor antagonist[1].Formula:C14H20O3Color and Shape:SolidMolecular weight:236.31Mepixetil
Mepixetil is a potent angiotensin II receptor antagonist[1].Formula:C12H18N2O3Color and Shape:SolidMolecular weight:238.28LY2066948
CAS:LY2066948 is a selective oral estrogen receptor modulator (SERM) with high affinity for estrogen receptors ERα and ERβ (Ki of 0.51 and 1.36 nM, respectively) and displays potent anti-estrogenic activity. It effectively blocks the increase in uterine weight induced by ethinylestradiol in immature rats. LY2066948 is utilized in the research of uterine fibroids and myomas.Formula:C30H31NO5SColor and Shape:SolidMolecular weight:517.64
